[Treatment of diabetic gangrene].
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Biomedical subjects
Publications and source records attributed to A Olszewski.
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The influence of angiotensin on the central action of acetylcholine was studied in rats. It was shown that the action of acetylcholine was enhanced in animals treated simultaneously with angiotensin. Above phenomena were accompanied with the increase of "free" and "bound" acetylcholine in the brain of angiotensin treated rats. These observations indicate an interaction between angiotensin and acetylcholine in the CNS.
Competitive inhibition and exchange transport between arginine and lysine in the process of absorption from the caecum in pigs. Acta Physiol. Pol., 1978, 29 (2): 161--165. Arginine competes with lysine in the process of transport across the mucosal epithelium of the pig caecum, and the ability of arginine absorption is much greater than that of lysine. Absorption of large amounts of arginine causes secretion of large amounts of lysine into the intestinal lumen in the process of primary active exchange transport. Lysine is better absorbed from solution containing no other amino acids than from solutions containing mixtures of amino acids. Basic amino acids (Arg, Lys, His) stimulate the absorption of serine and threonine from the caecum of pigs.
Interrelationships between amino acids absorbed from the isolated pig caecum in situ. Acta Physiol. Pol., 1978, 29 (2): 167--176. Amino acids are absorbed selectively from the caecum of pigs depending on their qualitative and quantitative composition in the intestinal contents. Signigicant interrelationships were found between the absorption of different amino acids. Tyrosine exerted a significant stimulating effect on the absorption of most amino acids absorbed from the caecum, e.g. Asp-NH2, Ser, Thr, Arg, Asp, Glu. An increased absorption of Ser and Thr caused a rise in tyrosine absorption. The absorption of serine and threonine stimulated the absorption of arginine. Serine and threonine competed in the process of absorption, and the activity of serine in this process was much higher, in comparison with that of threonine. Secretion of amino acids back into the intestinal lumen was demonstrated.
Absorption of amino acids in isolated pig caecum in situ. Effect of concentration of enzymatic casein hydrolysate on absorption of amino acids. Acta Physiol. Pol., 1978, 29 (1): 67-77. The absorption of amino acids in the pig caecum was studied in situ after surgical isolation of the caecum from the remaining digestive tract and fitting of fistula to the isolated bowel sac. It was found that amino acids can be absorbed in the caecum. Amino acids possessing an additional functional group mainly: asparagine, serine, threonine, tyrosine, arginine, histidine, lysine and aspartic acid, were absorbed while the remaining ten determined amino acids were not absorbed under these conditions. The movement of water across the wall of the caecum and the osmotic pressure in the caecum had no effect on the absorption of amino acids. The absorption of water in the caecum is mainly due to simple diffusion.
The activity of acetylcholinesterase was assessed in the rat brain in nephrogenic hypertension and after angiotensin administration. No significant differences were found in relation to corresponding control groups.