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Biomedical subjects

A Patil

Publications and source records attributed to A Patil.

29 records · Page 2Linked to original sources
PubMed1992

The value of intraoperative scans during CT-guided stereotactic procedures.

The accuracy stereotactic procedures performed during the pre-computed tomography (CT) era was confirmed by intraoperative X-ray pictures. With the availability of CT it is now possible to confirm the position of the probe-tip on an image of the target. For biopsy of small lesions in critical areas of the brain, permanent placement of radioactive seeds, or thalamotomy, it would be desirable to have confirmation of the site of the probe-tip prior to performing the main step of the procedure. Intraoperative CT was performed in 216 stereotactic procedures carried out on the scanner table including biopsies, aspiration of cysts, brachytherapy, aspiration of abscesses, thalamotomy, and evacuation of intracerebral hematoma. In 6 cases, inaccuracies were detected, which it was possible to correct so as to place the probe where desired.

Adolescent↗
PubMed1992

Stereotactic microsurgical resection of intracranial tumors using the electromagnetic field focusing system.

The intense heat produced at the tip of the electromagnetic field focusing (EFF) probe at its point of contact with tissue can cut and vaporize tissue and coagulate blood vessels. As the probe is shaped like a bayonet and has a diameter of 0.3 mm at its tip, it can be used on deep structures through narrow openings, making it ideal for stereotactic craniotomy. Thirteen stereotactic craniotomy procedures using the EFF system were performed. Locations of the lesions were deep in the cerebrum, cerebellum and in the lateral ventricle. The system proved efficient with reduced blood loss and unobstructed view of deep structures. No complications resulted from the use of the system.

Brain Neoplasms↗
PubMed1990

Electromagnetic field focusing system in clinical neurosurgery--preliminary report.

The electromagnetic field focusing system is capable of sharply focusing induced current resulting in pinpoint heating of tissue. This heat can cut and vaporize tissue while simultaneously coagulating vessels. This is a report on the first 15 consecutive neurosurgical cases where this system was used for tumor excision. The system was found to be an effective and safe surgical tool. It functioned effectively, even under saline and cerebrospinal fluid and through narrow openings during stereotactic microsurgical procedures.

Adult↗
PubMed1990

Histological and bacteriological studies of burn wounds treated with boiled potato peel dressings.

Histological and clinical studies have been made on comparable burn wounds covered with either boiled potato peels affixed to gauze bandages or gauze dressings alone; both dressings were applied over a thin layer of 5 per cent silver sulphadiazine. Compared with treatment with plain gauze dressings, the application of the potato peel dressing reduced or eliminated dessication, permitted the survival of superficial skin cells and hastened epithelial regeneration. Bacteriological studies showed that the potato peels had no intrinsic antibacterial activity, the wounds beneath both dressings showing either no growth or, on most occasions, the same bacterial species. The easy availability of potato peels and gauze bandages on to which they can be affixed, the simplicity of the preparation of this dressing, the ease of sterilization and its low cost of production make this the dressing of choice for burn wounds in our developing country.

Adolescent↗
PubMed1988

Electromagnetic field focusing (EFF) probe for intravascular endarterectomy. Preliminary feasibility study.

Vaporization of atheromas in 10 human aorta segments immersed under flowing blood in vitro were done using the EFF probe. No increase in packed cells of the flowing blood following atheroma vaporization were noted suggesting absence of post vaporization debris. No damage to the aorta underlying the vaporized atheroma was noted on light microscopy suggesting well localized vaporization process. This study suggests that EFF probe might be a safe tool for intravascular endarterectomy.

Aortic Diseases↗
PubMed1987

The study of the effect of human chorionic gonadotrophic (HCG) hormone on the survival of adrenal medulla transplant in brain. Preliminary study.

Autologous adrenal cortex was completely dissected off the medulla using microdissection. The adrenal medulla tissue was transplanted to the lateral ventricle in twenty-one adult rats. Group A consisting of ten animals received 200 units of HCG per 100 gram body weight daily for one week and then on every alternate day for seven weeks. The remaining rats (group B) served as control. After eight weeks the brains were removed and a volumetric study was done using histological sections. High pressure liquid chromatography (HPLC) with electrochemical detection for catecholamine assay of the graft was also undertaken. The graft survival in group A was significantly higher (p less than 0.005) than group B. The level of norepinephrine was significantly higher in group A while dopamine was higher in group B. The higher volume of graft tissue in group A suggests that HCG may help in increased survival and growth of the transplanted tissue. Higher levels of norepinephrine in group A would suggest a tendency for such grafts to be active to a greater extent with the treatment of HCG.

Adrenal Medulla↗
PubMed1984

Recoiling suture and methylmethacrylate in aneurysm thrombosis. Preliminary report.

Injection of acrylic material into the aneurysm is a relatively simple procedure if escape of the material into the circulation can be prevented by means of a coil inserted into the aneurysm prior to injection of the acrylic material. In the present study, polypropylene (00000) suture was given a coiling property. On extrusion through a 22 gauge spinal needle the suture regained its coiled shape. Experiments were carried out on dogs with the external carotid artery serving as a model for an aneurysm. Using a 22 gauge spinal needle, first the coiled suture was inserted into the aneurysm and then methylmethacrylate was injected. Ten aneurysms were thrombosed. None of the animals suffered a neurological deficit. Complete thrombosis of the aneurysms were noted in all the animals. On perfection, this technique could eventually be used for stereotaxic thrombosis of intracranial aneurysms.

Animals↗
PubMed1981

Tricuspid regurgitation by radionuclide angiography and contrast right ventriculography: a preliminary observation.

In a retrospective study correlating the degree of tricuspid regurgitation seen on first-pass radionuclide angiography with that seen on contrast right ventriculography in 51 patients, ten had no tricuspid regurgitation by contrast ventriculography, whereas by radionuclide angiography nine had no regurgitation and one had minimal regurgitation. Of eight patients with minimal tricuspid regurgitation by contrast ventriculography, five had minimal regurgitation by nuclide angiography and three had no regurgitation. Of the 11 patients with mild to moderate tricuspid regurgitation by contrast studies, ten had mild to moderate regurgitation and one had severe regurgitation by nuclide angiography. Of 22 patients with moderate to severe tricuspid regurgitation by contrast studies, 15 had moderate to severe regurgitation and seven had mild to moderate regurgitation by nuclear angiography. In this preliminary study comparing radionuclide angiography with contrast right ventriculography, there were three false-negative and one false-positive nuclide angiograms, giving a sensitivity of 93% and a specificity of 90%.

Adult↗