[Influence of food composition on carbohydrate and fat metabolism].
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Biomedical subjects
Publications and source records attributed to A Pohl.
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Of a total of 24 newborn with neonatal bacterial infectious syndrome (NBIS), in 157 (65.12%) the infection appeared immediately at birth. In the rest of 84, the clinical manifestations appeared in the first 4 days of life followed in decreasing order by systemic manifestation without location on pneumonia and bronchopneumonia were the most frequently diagnosed, an organ, septicemias and meningitis, infectious jaundice, etc. Two antibiotics were associated in the severe forms, and antiinfectious monotherapy was used in the milder ones. In the cases with unfavourable clinical evolution, the antiinfectious treatment was used. The severe forms of NBIS were among the most cases of death at this age. NBIS manifested, therefore, under various forms, imitating other noninfectious affections. During diagnosis, mother's anamnestic data, and very often the clinician's intuition were very important, before the bacteriologic corroboration.
The diagnosis of infectious bacterial neonatal syndrome (IBNS) was based on 3 arguments: --the suggestive anamnestic investigation of the mother; --clinical signs revealing the infection in the new-born child; --paraclinical data. The evoking anamnestic data during pregnancy and parturition are highly important. Of them, the most frequently met were: premature rupture of the membranes, modified amniotic liquid; with or without premature rupture of the membranes, urinary infections declared but not sufficiently treated, fever and pseudoinfluenza syndrome in the last term of the pregnancy etc. The clinical signs revealing the infection in the new-born are: disturbance in the behaviour and the proper clinical signs. Of the clinical data the authors followed the evolution of the hematologic data, the inflammatory test--serologic and bacteriologic (the greatest importance was given to the blood cultures and seeding in CSF). Therefore, IBNS transmitted through the mother-fetal route can be suspected only in the presence of conclusive anamnestic data. The clinical aspects, sometimes minor, corroborating the clinical evolution and the paraclinical data are of the greatest importance for the physician's decision. The clinical diagnosis based on serious clinico-anamnestic arguments should not be ignored by negative bacteriologic tests.
The paper reports on a case of infantile cortical hyperostosis (Caffey's disease) diagnosed on the basis of clinical and typical radiological data, and benign and without treatment suggestive evolution by leaps. The appearance of the disease in several members of the same family pleads for its hereditary character.
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