[Theoretical and practical significance of the theory of cytotoxins].
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Biomedical subjects
Publications and source records attributed to A Sh Zaĭchik.
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Radioimmunoassay was used to determine the blood gastrin content in 45 patients and 14 healthy individuals. Examination was performed on an empty stomach and 20 and 40 minutes after trial breakfast. It was established that after the trial breakfast (35 g protein, 50 g fat, and 70 g carbohydrate) the greatest increment in the gastrin content, as compared to normal, was recorded in increased acid-forming gastric function (peptic ulcer with ulcer site in the duodenum). In patients with decreased acid production (peptic ulcer with ulcer site in the stomach, chronic gastritis with secretory failure), the gastrin content after the trial breakfast was lower than in healthy individuals and in duodenal ulcer patients.
The interaction of specific immunoglobulins G to the histone H1 with the thymocytes of intact animals has been demonstrated to increase the reception of acridine orange (AO) in nuclear chromatin. This raises the rate of AO fluorescence and lowers the level of light polarization. This may result from occurring decondensation processes. On the other hand, the interaction of antihistone antibodies with irradiated rat thymocytes causes no changes in the package of nuclear chromatin, which is likely to be due to destructive processes which take place in the cells in response to radiation. The immunoglobulins G to the core histone H2B produce an insignificant effect on the condensation rate of the nuclear material of thymocytes both from intact and irradiated animals.