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Biomedical subjects

A Stenström

Publications and source records attributed to A Stenström.

At least 73 records · Page 4Linked to original sources

Influence of alpha-MSH and ACTH on cortical bone remodelling in hypophysectomized rats.

Hypophysectomy increases both periosteal resorption and endosteal apposition along the femur diaphysis in rat. Administration of alpha-MSH decreased the periosteal resorption but had no effect on the endosteal apposition. ACTH had only minor effects on the endosteum. Thus, alpha-MSH and ACTH, in the doses used, have different effects on cortical bone in rat. The effect of alpha-MSH on cortical bone could be an effect of the hormone alone or by its stimulation of other factors.

Adrenocorticotropic Hormone↗

Effect of pituitary hormones on dentin production in maxillary incisors in the rat.

The effect of pituitary hormones on dentin production and longitudinal growth of the maxillary incisors in normal and hypophysectomized rats was investigated. Bovine growth hormone was found to increase the dentin production slightly in normal rats and significantly in hypophysectomized rats. Other pituitary hormones showed no effects on dentin apposition in the doses and periods tested. The effects of the pituitary hormones on the longitudinal growth of the tooth were small or insignificant. The effects of growth hormone on the dentin apposition and the longitudinal growth of the tooth after hypophysectomy were smaller than the effects on longitudinal bone growth and cortical bone remodeling, indicating different sensitivity to hormones between different mineralized tissues.

Age Factors↗

Effect of thyroxine and growth hormone on dentin production in maxillary incisors in the rat.

Dentin production and longitudinal growth of maxillary incisors in female rats, age 60--95 d, were determined by the tetracycline technique in hypophysectomized rats after administration of growth hormone and thyroxine during age 75--95 d. Hypophysectomy was performed at age 60 d. Administration of thyroxine resulted in a considerable increase in dentin apposition and longitudinal growth of the tooth. The same effect, but somewhat lower, was registered for growth hormone. Growth hormone and thyroxine administered simultaneously had an additive synergistic effect. Compared with the effect of hypophysectomy and of hormone administration on longitudinal bone growth and cortical bone remodleing the effect on dentin production and longitudinal growth of the maxillary incisors in the same rats is less pronounced and shows a different pattern in reaction, indicating differences in sensitivity for different cell systems and difference in endocrine control.

Animals↗

Meniscectomy. A comparison of two series treated as outpatients and inpatients.

A total of 129 patients were operated on for meniscus lesion in the knee joint. Of these, 64 were operated as outpatients and 65 as inpatients. The outpatients reported to the operation department in the morning and left the hospital in the evening of the same day, after the operations. The inpatients were admitted to the hospital the day before the operation and were discharged 1--3 days after the operation. Objective postoperative findings, sick-leave periods and the number of visits to the outpatient clinic show no differences between the groups. The end result in the two groups is the same. This investigation also shows that it is possible to operate on patients with meniscus injury as outpatients without increased discomfort for the individual and without medical risks. Thus expensive nursing resources are released for other groups requiring more nursing care.

Adult↗

Effect of fracture on longitudinal bone growth in rats.

The growth rate in proximal tibia and distal radius in rats was investigated by the tetracycline method after femoral fracture, tibiofibular fracture, and metatarsal fracture. Up to 1 to 2 weeks after the fracture, a higher growth rate was recorded on the fractured side than on the unfractured side. This effect occurred later after tibiofibular fracture than after femoral and metatarsal fracture, but was almost of the same size and about 8 per cent of the normal growth rate. This difference in growth rate was caused partly by a general group retardation compared with the normal growth rate, and partly by a local growth stimulation in the fractured extremity. The growth retardation was pronounced after tibiofibular fracture, but was insignificant after femoral and metatarsal fracture. The growth rate on the fractured side after the latter two types of fractures was higher than under normal conditions. Thirty days after all types of fractures, the growth rate was normal, both in fractured extremity and in other growth regions.

Age Factors↗

Effect of venous stasis on longitudinal bone growth in the rabbit.

The effect of ligation of veins on the longitudinal bone growth was studied in growing white rabbits. The daily longitudinal bone growth was determined with the tettacycline technique from the day before up to 40 days after operation. Ligation of the femoral vein, the circumflexal veins, and the deep femoral vein resulted in a temporary venous stasis. Additional ligation of the sciatic vein resulted in the same degree of venous stasis but a more longstanding effect. Neither of the operations resulted in growth stimulation or growth retardation compared with the control side. On the contrary, the ligation resulted in a minor temporary general growth retardation during the first days after the operation.

Animals↗