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Biomedical subjects

A Stepień

Publications and source records attributed to A Stepień.

At least 55 records · Page 3Linked to original sources
PubMedDate not supplied

[Sleep disorders as a risk factors for stroke].

Sleep-disordered breathing seems to play a role in pathogenesis of stroke: for example, it was showed that snoring is a risk factor for stroke. Sleep disorders and sleep-disordered breathing increase the risk for stroke, probably by influencing systemic and cerebral blood circulation, causing hypoxaemia during night. This theory is supported by the fact of higher prevalence of stroke in the morning. During REM sleep there is a higher requirement for oxygen; as most sleep apnoeas occur during REM, it is possible that there is a relative hypoxaemia during this sleep stage. Stroke, including hemispheric stroke, can cause or aggravate the pre-existing sleep-disordered breathing. There are contradictory data in the literature regarding the influence of stroke on sleep architecture. Sleep disorders are associated with poorer stroke outcome, so their detection and treatment can be important in secondary stroke prophylaxis and will improve the patient's functioning and quality of life.

Brain↗
PubMedDate not supplied

Influence of the therapy with pergolide mesylate plus L-DOPA and with L-DOPA alone on serum cGMP level in PD patients.

The aim of our study was to investigate serum cGMP level in patients treated with L-DOPA alone and L-DOPA with pergolide mesylate (PM) and to compare the obtained values with age-matched healthy subjects. PD patients treated with L-DOPA or with PM + L-DOPA had significantly higher cGMP levels in serum as compared to control. Moreover, cGMP level was significantly higher after treatment with PM + L-DOPA then L-DOPA alone. We did not observed significant differences in UPDRS scores between both PD groups. Our data suggest that changes in serum cGMP level in PD patients are related with PM + L-DOPA or L-DOPA alone therapy.

Aged↗
PubMedDate not supplied

[Chromolipids].

Explore the source record for details and available documents.

Acid Phosphatase↗
PubMedDate not supplied

[A case of suspected Machado-Joseph disease? (Case report for discussion)].

The reported case had extrapyramidal signs and sensorimotor peripheral neuropathy, and it seems to be a genetic disorder separate from the Machado-Joseph disease. Abnormalities of CSF were found, and EMG showed a sensorimotor neuropathy. MRI of the brain demonstrated hypodense lesions in the lentiform nucleus of the left hemisphere.

Adult↗
PubMedDate not supplied

[Analgesic effect of imipramine in the treatment of ischium pain and circadian rhythm of cortisol release into the serum].

In the paper the results are presented of treatment of ischialgia with Imipramine, taking into account the circadian rhythm of cortisol release into the serum. The obtained results encourage to the use of tricyclic antidepressants in the treatment refractory cases of ischialgia. No significant differences were observed in the circadian rhythm of cortisol release into the serum before and after the treatment with Imipramine.

Adult↗
PubMedDate not supplied

[Dexamethasone test in the assessment of depression grade in patients with low back pain].

The results of the dexamethasone test were compared with the depression depth and pain intensity in patients with low back pain caused by degenerative changes and/or disc prolapse. In the light of these studies no correlation was demonstrated between the positive results of the dexamethasone test and depression symptoms and the intensity and duration of pain.

Adult↗
PubMedDate not supplied

[Assessment of dexamethasone effectiveness in the treatment of ischalgia].

The authors studied 43 patients admitted to hospital with acute episodes of ischalgia or recurrences caused by intervertebral disc disease. The patients were randomly selected into two groups treated with dexamethasone in high but rapidly decreasing doses, or tramadol. A comparison of the results in both groups showed that dexamethasone was effective and safe when given by this method to patients with ischalgia.

Adult↗
PubMedDate not supplied

[Recurrent painful ophthalmoplegia (Tolosa-Hunt syndrome)].

A case is presented of recurrent painful ophthalmoplegia of atypical course, with pain in the orbit, eyelid oedema, and paralysis of external eye muscles. Disease symptoms occurred intermittently in both eyeballs. The performed MRI examination showed the presence of inflammatory focus in the posterior ethmoid.

Adult↗