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Biomedical subjects

A Szelier

Publications and source records attributed to A Szelier.

9 recordsLinked to original sources
PubMed1994

The natural history of postischemic T-wave inversion: a predictor of poor short-term prognosis?

BACKGROUND: This study followed up the natural history of T-wave inversion and assessed the short-term prognosis associated with the condition. METHODS: Forty patients with acute ischemic syndrome, without infarction, and with postischemic T-wave inversion (group 1) were followed during the persistence (inverted T-wave period) and after the resolution of T-wave inversion (positive T-wave period). Another 40 patients with acute ischemic syndrome, without infarction and with normal T waves (group 2), were also followed. RESULTS: Postischemic inverted T waves showed resolution within 3-21 days of presentation in 31 patients from group 1 on medical treatment alone. Further ischemic events (acute myocardial infarction, acute ischemic syndrome, angina pectoris, silent ischemia), inducible ischemia (during treadmill test), wall-motion abnormalities (demonstrated by echocardiography), all developing in the primarily ischemic myocardial area, were more frequent (P < 0.02) in group 1 patients during the inverted T-wave period compared with those experienced in the positive T-wave period of group 1 patients, and compared with group 2 patients. CONCLUSION: In most patients on medical treatment, postischemic inverted T-waves tended to resolve within 3 weeks. The presence of postischemic inverted T waves appears to be an independent marker of further ischemic events.

Adult↗
PubMed1993

[Postischemic inverted T waves: does gradual regression indicate improved prognosis?].

This study has followed up the natural history of postischemic inverted T waves and assessed the prognosis. 40 consecutive patients with unstable angina with postischemic precordial inverted T waves in the noninfarcted, previously ischemic area were followed during the persistence (negative T wave period) and after resolution of inverted T waves (positive T wave period). The outcome with frequencies of acute myocardial infarction, acute ischemic syndrome, angina pectoris, positive exercise test, silent myocardial ischemia, anterior wall motion abnormalities on echocardiogram, positive coronary arteriography were determined and compared in the negative versus positive T wave periods. Postischemic inverted T waves showed resolution within the postischemic 3-21 days (at a mean of 10.6 days) in 31 patients on medical treatment alone during the whole study period. Frequencies of parameters/patients determined in negative versus positive T wave periods are as follows: acute myocardial infarction: 5/40 versus 0/31 (non significant), acute ischemic syndrome: 25/40 versus 2/31 (p < 0.001), angina pectoris: 32/40 versus 11/31 (p < 0.001), positive treadmill exercise test: 14/16 versus 14/30 (p < 0.02), silent myocardial ischemia: 14/14 versus 16/31 (p < 0.01), hypokinesis 26/34 versus 4/24 (p < 0.001), positive coronary arteriography: 4/4 versus 11/11 (non significant). In most patients on medical treatment, the postischemic inverted T waves tend to resolve within 3 weeks. Attention has to be paid to the patients with postischemic inverted T waves during the negative T wave period: the high ischemic risk gradually decreases with resolution of negative T waves.

Angina, Unstable↗
PubMed1991

[Significance of the ECG in the diagnosis of so-called "stunned myocardium"].

The common feature of these 3 case reports can be characterized by the negative symmetric giant T waves developing 1-2 days after an acute myocardial ischemic attack, producing no enzymatic evidence of necrosis, persisting for several days or some weeks. The negative transient T waves are considered to fulfil neither the classical electrocardiographic characteristics of acute or chronic myocardial ischemia nor the criteria of subendocardial necrosis, but are believed to designate the existence of myocardial stunning. The authors suggest, that transient Q waves having been declared as the only electrocardiographic marker of myocardial stunning, reflect severe "transmural stunning" and can be detected relatively rarely, for a short time. In contrast, the transient negative T waves reflect "subendocardial stunning" and can be documented more frequently, persist for a longer time, and therefore could be a simple and sensitive method in detection of myocardial stunning.

Adult↗
PubMed1990

[A case of surgically treated septum perforation associated with acute myocardial infarct].

The authors present the case-history of an elderly female patient with acute myocardial infarction complicated by ventricular septal defect (VSD). She was operated on in order the VSD to be corrected but--probably because of sutural insufficiency--it temporarily reopened, later closed spontaneously. The significance of certain tests in the differential diagnosis of systolic murmur after acute myocardial infarction is discussed, and the importance of these findings compared to the clinical picture is emphasized.

Aged↗
PubMed1989

[Successful surgical management of rupture of the papillary muscle diagnosed by ultrasound].

The rupture of the papillary muscle is an infrequent complication of myocardial infarction. Survival of the acute phase depends on the severity of the rupture and the remaining function of the left ventricle. Permanent survival may be ensured however only by surgical intervention. The authors present the case record of a patients whose disease in connection with a myocardial infarction was revealed by echocardiography and was operated on successfully. No such data were found in the Hungarian literature.

Humans↗
PubMed1989

[ECG characteristics of acute myocardial ischemia].

UNLABELLED: The authors discussed the efficacy of ECG in distinction of reversible and irreversible myocardial damage. On the basis of continuous ECG monitoring of a patient, suffering from acute ischemic syndrome, it was established, that neither the appearance of R wave reduction nor that of the transient Q wave (besides the widely accepted ST segment elevation) do not signify the fact of transmural myocardial infarction. IN CONCLUSION: the classical rules in indication of myocardial rescue therapy should be expanded and ECG monitoring is of crucial importance in indication and evaluation of myocardial rescue therapy in acute myocardial ischemic syndrome.

Electrocardiography↗
PubMed1989

[New aspects of the Kearns-Sayre syndrome].

The case report of the 23 years old female with Kearn-Sayre syndrome started about 15 years ago has some special cardiological aspects. By His band ECG the height of III. degree atrioventricular block was located in the atrioventricular node which is in sharp contrast with all former findings localizing the block into or distal to His band. In the pathogenesis of the unexpected block localisation--besides the muscular degeneration accepted generally in KSS--the recent myocardial infarction of the patient could have a causal role. Electronmicroscopical investigation carried out on the biopsy specimen from the right ventricle revealed both the characteristic hallmarks of "generalized mitochondriopathy" and the pathological glycogen accumulation having been published in skeletal muscles before. The mitral valve prolaps diagnosed in the patient has never been mentioned in KSS. Trauma suffered in early childhood might have a pathogenetic role. In discordance with literature steroid treatment of the diabetic patient with KSS didn't result in lactacidosis.

Adult↗