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Biomedical subjects

A T Tananov

Publications and source records attributed to A T Tananov.

At least 37 records · Page 2Linked to original sources
PubMed1982

[Multiple sclerosis and the histocompatibility system].

Examination of the histocompatibility antigens carried out in 62 patients of the Russian nationality suffering from disseminated sclerosis showed that the HLA-B7 antigen was encountered in them more frequently than in healthy people. The distribution of the A2 and A3 antigens of the HLA system was different depending on the character of the disease course, the A2 antigen was prevalent in a relatively benign, remitting process, while prevalence of the A3 antigen was characteristic for rapidly progressing processes that led to grave affections of the nervous system. In the patients' families two haplotypes, i. e. A2B7 and A3B7 were found to be prevalent.

Adolescent↗
PubMed1981

[Risk of meningococcal infection in children with different hla phenotypes].

A total of 104 children aged 4 months to 13 years with meningococcal infection were examined. For control 600 healthy donors were used. Histocompatibility antigens were determined by the lymphotoxic test. Altogether 36 antigens of the loci, A, B and C were determined. The data thus obtained indicate that the risk of contacting the infection is 6 times greater for persons with Hl A-Bw16 phenotype and 3 times greater for persons with HL A-A12 phenotype than for persons with Hl A-A1 phenotype.

Adolescent↗
PubMed1981

[Histocompatibility antigens in multiple sclerosis patients].

Studies of histocompatibility antigens in 25 patients, Russians by nationality, suffering from multiple sclerosis showed that antigens HLA-B7 were found in them more frequently than in healthy subjects. Also prevalence of antigens A2 and A3 was noted in the patients, each antigen being prevalent depending on the process type. Antigen A2 was prevailing in patients with a relatively benign process, while antigen A3 was predominant in patients with a rapidly progressing disease that led to grave affections of the nervous system.

Adolescent↗
PubMed1978

[Detection of isoimmune antibodies against a population of human B-lymphocytes].

Rosette-forming ability of human lymphocytes was tested before and after their sensitization with isoimmune sera against histocompatibility antigens. Anti-HLA sera inhibited the ability of T- and B- lymphocyteè to form rosettes. Some sera inhibited rosette formation mostly of B-lymphocytes; they also possessed marked capacity to react with B-lymphocytes population in prolonged lymphotoxic tests.

Antilymphocyte Serum↗