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Biomedical subjects

A Wolpowitz

Publications and source records attributed to A Wolpowitz.

At least 19 recordsLinked to original sources

Pulmonary sequestration causing congestive heart failure in infancy: a report of two cases and review of the literature.

Congestive heart failure as a presenting symptom in infants with pulmonary sequestration is rare, and the cases of only 3 such patients have been reported. The clinical features, hemodynamics, and management of two additional patients are described. Both were seen in severe congestive heart failure in the absence of any associated cardiac anomalies. The physical findings, plain roentgenograms, electrocardiograms, and echocardiograms may provide some diagnostic clues, but cardiac catheterization is the essential diagnostic investigation. In 1 patient, pneumonectomy was performed because of extensive changes throughout the affected lung. In the other, ligation of the anomalous systemic artery to the sequestered lobe was the only surgical procedure. Both patients are doing well 15 months and 18 months after operation. Success with the latter surgical approach has not been reported previously.

Bronchopulmonary Sequestration↗

The present status of heterotopic cardiac transplantation.

In the period November, 1974 to May, 1980, 30 patients underwent heterotopic heart transplantation at Groote Schuur Hospital. One patient subsequently underwent retransplantation for rejection. There were no operative deaths. Fifteen patients are alive 4 months to almost 5 1/2 years after transplantation. The 1 year survival rate has been 61%. Three of six patients have survived for more than 4 years. Eight of nine patients whose initial transplant operation was performed during the past 18 months remain alive. Seven patients died from infection, five from rejection, and three from other causes. The advantages of heterotopic over orthotopic heart transplantation, in particular in allowing patients survival even after graft destruction by irreversible rejection, are discussed.

Adult↗

Carcinoma of the oesophagus.

A survey of carcinoma of the oesophagus at Kalafong Hospital revealed a greater incidence of the disease in males, being highest in the age group 50 - 59 years, with the middle third of the oesophagus the most prevalent site and with oesophagotracheal or oesophagobronchial fistulae a common complication.

Adolescent↗

Annular subvalvular idiopathic left ventricular aneurysms in the black African.

The case of a Black African patient with an annular subvalvular left ventricular aneurysm of unknown origin is described, and the pathological findings in this condition together with a review of the literature is presented. We have operated on 12 patients with this condition between 1958 and 1978. Ventricular aneurysm in the Black African is extremely rare; aneurysms resulting from ischemic heart disease have not been encountered in this racial group, and contrary to earlier reports in the literature, syphilis is not the most common cause of left ventricular aneurysms in this group. The aneurysms arise in the fibrous rings below either the aortic or the mitral valve, extend around the valves in this situation, and may occur either singly or in both positions in the same heart. After various etiological factors are excluded, it is probable that in this group of patients the aneurysms develop initially as pulsion diverticula through a congenital weakness in the ventricular wall in the region of the atrioventricular groove.

Adult↗

Heterotopic versus orthotopic heart transplantation.

Since November 1974, heterotopic cardiac transplants have been performed at this unit in preference to orthotopic transplants. A number of reasons have led us to prefer this technique, namely donor malfunction in the immediate postoperative period and during rejection; right ventricular failure of the donor heart in the orthotopic position in patients with pulmonary hypertension; the ease of patient management; and the use of the donor heart as a temporary method of cardiac support. Disadvantages are the later recognition of rejection and the difficulty in performing transvenous endomyocardial biopsies. The results are satisfactory giving a 1, 2, and 3-year survival rate of 62%, 58%, and 50%, respectively.

Graft Rejection↗

A review of experience with cardiac transplantation.

Despite the hazards of rejection and the complications of immunosuppression, cardiac transplantation is the only available treatment for myocardial disease that is refractory to medical therapy and in which no other form of surgery can be offered. There are disadvantages to orthotopic cardiac transplantation, which have led to the development by this department of the heterotopic cardiac transplant, which functions as a natural left-heart and right-heart assist device. The results of 19 cases are presented.

Adult↗

Spina bifida occulta.

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Black or African American↗

Pelvic displacement of a cardiac pacemaker following trauma. A case report.

The rate migration of an implanted cardiac pacemaker from the subrectus area anterior to the peritoneum to the pelvis following a motor vehicle accident is reported. Discovery of dislodgement was made by observing a marked increase of pacemaker impulse amplitude in the three standard limb leads as measured on an oscilloscope.

Abdominal Muscles↗

Left innominate vein (brachiocephalic) monitoring of central venous pressure after cardiac operations.

Pre-operative insertion of a central venous pressure monitoring line may be difficult when superficial veins are lacking. Groin cannulations predispose to bacterial endocarditis, and are difficult to keep from becoming obstructed by hip flexion. Internal jugular lines are precarious and tend to be unreliable. Innominate vein cannulation before cardiac surgery is safe, easy to perform, reliable and comfortable for the patient. Complications have not been encountered.

Brachiocephalic Veins↗

Spina bifida occulta.

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Black or African American↗

Trans-septal monitoring of left atrial pressure after cardiac surgery. An alternative method.

A simple, safe method for trans-septal insertion of a left atrial pressure line in 25 patients is presented. Complications have not been noted. Monitoring of left atrial pressure is often desirable after cardiac surgery. The conventional lateral approach is associated with the risk of haemorrhage after the cannula has been withdrawn. In an oversensitive heart manipulation might not be tolerated, precluding placement of the cannula.

Blood Pressure↗