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Biomedical subjects

A el Mouaaouy

Publications and source records attributed to A el Mouaaouy.

11 recordsLinked to original sources

[Endoscopic sonography of the anorectum in inflammatory rectal diseases].

213 patients, classified in 3 groups, were examined in a prospective trial using endorectal ultrasound. 80 patients (group A) had no anorectal disease, the endorectal ultrasound showed normal structures of the anorectum and the perirectal tissue. 80 patients (group B) suffered from Crohn's disease, 30 of them had no clinical signs, the rest of this group (50 patients) felt pain in the anal/perianal region. 83 patients (group C) had perianal abscesses or fistulas, Crohn's disease could be excluded. In all 64 perianal fistulas and 66 perianal abscesses were diagnosed. The results of the rectal-proctological examination were compared with endorectal ultrasound. 100% of the perianal abscesses could be recognized using endosonography. The digital-proctological examination revealed only 57% of perianal abscesses and 48% of perianal fistulas; the supralevatory abscesses couldn't be detected proctologically at all. By endorectal ultrasonography we obtained useful informations about localization and extension of the inflammatory process. From a therapeutic and prognostic view the endorectal ultrasound is a simple, practicable and useful method to investigate perianal and anorectal diseases.

Abscess↗

Value of sonography for follow-up examination after allogenic kidney transplantation.

In 66 patients with renal transplants 246 sonographic examinations were performed. The patients were divided into two groups based on their immunosuppressive protocol. Group I was treated with Cyclosporin A (CsA) and group II with azathioprin. A compensatory hypertrophy with a volume increase of 20% could be seen in nearly all grafts. During acute tubular necrosis only minimal sonographic changes could be found. In each group 16 patients developed an acute rejection episode. Sonographic signs of acute rejection were: (1) a hypoechoic enlargement of the renal pyramides; (2) an increase in cortical echogenicity; (3) an increase in graft volume greater than compensatory hypertrophy; (4) an indistinct parenchyma-pelvic border; (5) dilation of the pelvis with a parenchyma-pelvic index greater than 2.3:1 (in group II cases). Chronic rejection is characterized by graft shrinkage. No specific signs were evident. The increasing use of CsA diminishes the value of sonography in follow-up of acute rejection after kidney transplantation. Nevertheless, it is of great value for follow-up examination concerning other complications.

Azathioprine↗

Diagnosis of liver metastases from malignant gastrointestinal neoplasms: results of pre- and intraoperative ultrasound examinations.

In this prospective study, 108 patients presenting with gastrointestinal cancer were examined for liver metastasis before and during surgery. The investigations emphasized a comparison of pre- and intraoperative ultrasound (US) examinations. The results of intraoperative liver inspection and palpation served as control parameters. In addition, an exact description and characterization of the liver metastases was attempted. Liver metastases were found in 30 of the 108 patients (28%). They could be identified in 17 subjects by preoperative US (57% sensitivity), in 21 patients by intraoperative palpation and inspection (70% sensitivity), and in 27 cases by intraoperative US (90% sensitivity). We concluded that 7%-34% of patients with liver metastases can be identified with 95% reliability using intraoperative US alone or in combination with palpation and inspection.

Colorectal Neoplasms↗

Intraoperative echo-contrast ultrasound examination of malignant liver neoplasms--initial clinical experience.

The value of intraoperative echo-contrast ultrasound (US) as compared with plain US was studied in 19 patients presenting with malignant liver tumors. The contrast medium SHU 454 was intraoperatively injected via the portal venous system or the biliary tract. Using intraoperative echo-contrast US, extremely small liver tumors could be sought in a limited area of the liver. In comparison with plain US, the former technique resulted in better demarcation of especially small tumors, which were seen as echo-poor areas in relation to the surrounding liver tissue.

Bile Ducts↗

[Blunt abdominal trauma: differential diagnosis of splenic lobulation and splenic rupture].

In a retrospective study, we analyzed the data of 232 patients with blunt abdominal trauma between January 1, 1984, and December 31, 1988. In emergency ultrasound, we detected 4 patients with a smooth disruption of the splenic outline combined with free peritoneal fluid around the spleen. Because of the blunt abdominal trauma, a rupture of the spleen had to be excluded. In two of these 4 cases, we decided for laparotomy. Intraoperatively, we found a splenic lobulation and no splenic injury in both cases. We conclude that an emergency sonographic examination of the spleen, it should be kept in mind that the anatomical variation of a splenic lobulation might mimic a rupture of the spleen.

Abdominal Injuries↗

[Sonography in Crohn disease--the conclusions of an experts' group].

Sonography is adding a new dimension to diagnosis of Crohn's disease: the analysis of the transmural and peri-intestinal manifestations of the chronic inflammation. Distortions in the structure of intestinal wall are recognizable, the impact on transport of intestinal content can be judged, penetration of inflammation into the bowel surrounding as fistula, abscess, mesenteriitis und peritonitis is safely seen. Differential diagnosis on a strictly sonographic basis is difficult. The paper represents the results of an expert meeting held at the University of Frankfurt/M.

Crohn Disease↗

[Results of organ saving splenic surgery].

The charts of the 24 patients we treated in the past 7 years with spleen conserving methods after trauma and of the 13 patients we treated with splenic autotransplants were reviewed for this study. The results demonstrate, that the conservation of an injured spleen, desirable in adults too, is possible in appropriate cases without greater risk. Infrared coagulation and fibrin sealing proved as safe techniques, that can be augmented by others. Patients with subcapsular hematomas of the spleen can be left normally without operation in absence of other intraabdominal injuries; in these cases meticulous surveillance with the possibility of operations and ultrasound examinations at any time is necessary because of the risk of delayed bleeding. In the meantime we gave up the autotransplantation of splenic tissue after splenectomy for complications and doubts in the efficiency.

Adolescent↗

Rat liver model for testing intraoperative echo contrast sonography.

The present animal experimental study showed that intraoperative hepatic ultrasonography using an echo contrast medium can visualize small hepatomas (with a diameter of between 3 and 15 mm) induced in the rat liver, although they were not recognizable with plain ultrasonography. A homogeneous increase in the echogenicity of the liver tissue was achieved by using an echo contrast medium (Echovist) based on galactose microparticles. Self-made bubble preparations such as those used in echocardiography were far less effective. When the dosage was optimal (0.01-0.003 ml/g liver weight with concentrations of 200 and 300 mg/ml Echovist), homogeneous contrast enhancement of the liver was achieved for at least 10 min after a single bolus injection via all routes of contrast administration (hepatic artery, portal vein, bile duct). As a result, hepatomas appeared as hypodense formations (portal vein and bile duct) or as hyperdense zones (hepatic artery).

Animals↗

Intraoperative echotomographic diagnosis in abdominal and neurosurgery.

In many clinics, intraoperative sonography is used as a routine method in general surgery as well as in neurosurgery. The availability of sterilizable applicators in diverse shapes and sizes enables the optimal approach to the site to be examined. In processes involving the liver, the pancreas, the kidneys, or the brain, ultrasonic examination, together with an exact topographic localization, proved to be helpful in determining the dimensions of an altered structure. In patients with colorectal carcinoma, the discovery of metastases that had not been previously detected by percutaneous sonography proves the necessity of regular intraoperative ultrasonic examination to augment staging accuracy in tumor surgery.

Brain Neoplasms↗

[Intraoperative ultrasound diagnosis in neurosurgery].

Report on 71 successful intraoperative sonographies. The advantages of the technique were particularly evident when searching for tumours which were not visible from the brain surface. In these conditions intraoperative sonography greatly facilitates the planning of the operative approach. The ultrasound examination allows to distinguish tumour from peritumoral edema and healthy tissues. In one case it proved superior to nuclear magnetic and computer tomography in determining extent and infiltration. The technique proved nearly indispensable for intraoperative puncture.

Brain↗