Biomedical subjects

Alina Bakunowicz-Lazarczyk

Publications and source records attributed to Alina Bakunowicz-Lazarczyk.

22 records · Page 2Linked to original sources

PubMedDate not supplied

Optical coherence tomography measurement of the retinal nerve fiber layer in normal and juvenile glaucomatous eyes.

The aim of this study was to quantitatively assess and compare the thickness of the retinal nerve fiber layer (RNFL) in normal and glaucomatous eyes of children using the optical coherence tomograph. The mean RNFL thickness of normal eyes (n=26) was compared with that of glaucomatous eyes (n=26). The eyes were classified into diagnostic groups based on conventional ophthalmological physical examination, Humphrey 30-2 visual fields, stereoscopic optic nerve head photography, and optical coherence tomography. The mean RNFL was significantly thinner in glaucomatous eyes than in normal eyes: 95+/-26.3 and 132+/-24.5 microm, respectively. More specifically, the RNFL was significantly thinner in glaucomatous eyes than in normal eyes in the inferior quadrant: 87+/-23.5 and 122+/-24.2 microm, respectively. The mean and inferior quadrant RFNL thicknesses as measured by the optical coherence tomograph showed a statistically significant correlation with glaucoma. Optical coherence tomography may contribute to tracking of juvenile glaucoma progression.

Adolescent↗

PubMedDate not supplied

Use of optical coherence tomography in myopia.

PURPOSE: To measure retinal thickness and retinal nerve fiber layer thickness using optical coherence tomography in patients with myopia. PATIENTS AND METHODS: Thirty patients (13 girls and 17 boys) 14 to 18 years old were included in the study. The control group consisted of 15 patients. Each patient was subjected to routine ophthalmic investigations, which included the assessment of visual acuity for near and distant objects, autorefractometry, measurement of intraocular pressure, biometry, and assessment of the static visual field. The foveal retinal thickness and the peripapillary nerve fiber layer thickness were measured using optical coherence tomography. RESULTS: The mean foveal retinal thickness was 231.0 microm in eyes with low myopia, 218.0 microm in eyes with medium myopia, and 178.0 microm in eyes with high myopia. The mean thickness of the retinal nerve fiber layer was 150.0 microm, 140.0 microm, and 152.0 microm, respectively. Statistically significant differences were revealed between patients with high myopia and the control group. CONCLUSION: Optical coherence tomography can be employed to assess the retinal thickness and thus facilitate the detection of the evolution of alterations in myopia.

Adolescent↗

PubMedDate not supplied

Pediatric ophthalmologic findings of Cohen syndrome in twins.

We present the clinical findings and follow-up data of male twins with Cohen syndrome. The most characteristic ophthalmologic findings were down-slanting eyelids, lens opacities, chorioretinal dystrophy, pigmentary retinal deposits, pale disk, and bull's eye maculae.

Amblyopia↗

PubMedDate not supplied

[Dry eye syndrome in children with cystic fibrosis].

BACKGROUND: Cystic fibrosis is a white Caucasian population specific disease, with autosomal recessive mode of inheritance. It is caused by mutations in the protein coding gene of chromosome 7, functioning as the cystic fibrosis transmembrane conductance regulator (CFTR), causing dysfunction of secretory glands in the alimentary tract, respiratory tract and in the eye. PURPOSE: The aim of the study was to evaluate the tear film stability in cystic fibrosis patients. PATIENTS AND METHODS: Fifteen patients with cystic fibrosis aged 8-23, mean age 13.05 +/- 3.45, and fifteen controls aged 8-21, mean age 13.56 +/- 3.45 were examined. The tests included slit-lamp biomacroscopy, tear film break-up time, fluorescein staining and lissamine green staining. RESULTS: 54% Cystic fibrosis patients showed a statistically significant abnormal break-up time results. CONCLUSION: In cystic fibrosis patients we found low tear film stability. Fluorescine break-up time (FBUT) may be useful in the diagnosis of the dry eye in cystic fibrosis.

Adolescent↗