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Biomedical subjects

B Adamczyk

Publications and source records attributed to B Adamczyk.

At least 37 records · Page 2Linked to original sources
PubMed1980

Evaluation of antiviral substances against influenza A virus strains by the haemadsorption reduction test.

The haemadsorption reduction test with Ehrlich mouse ascites tumour cells proved to be a simple method for testing the sensitivity of influenza A virus strains to antiviral substances. Ribavirin and 2-deoxy-D-glucose were poorly effective in this system while all virus strains except A/PR/8/34 (H0N1) were highly sensitive to amantadine and rimantadine, the latter being the strongest inhibitor.

Amantadine↗
PubMed1980

Simple test for detection of virus neuraminidase and antineuraminidase using lectins (lectin-neuraminidase test system).

The fast and sensitive detection of virus neuraminidase effectiveness (influenza virus A and B or mumps virus) and of antibodies against virus neuraminidase in human serum is described. Lectin mainly obtained from Arachis hypogaea and Helix pomatia is used in the lectin-neuraminidase test (LN-test). The lectins are capable of agglutinating erythrocytes after virus incubation because virus neuraminidase reveals the T-antigen to be situated on erythrocytes. The presence of anti-neuraminidase in human sera can be detected with the aid of lectins after incubation of the virus suspension with human serum as a result of the agglutination having failed to take place. Neuraminidase activities of the influenza virus A and B are detectable up to a virus dilution of 1: 40,000 and anti-neuraminidase could be determined in human serum samples with titres of up to 1: 10,000. All materials required for the LN-test can be arranged in a set.

Animals↗