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Biomedical subjects

B Andersen

Publications and source records attributed to B Andersen.

At least 217 records · Page 12Linked to original sources
PubMed1975

An unusual outbreak of brucellosis.

A Brucella melitensis infection involved three persons. The infections were acquired by contact with a culture suspension that had been spilled during a laboratory exercise. One of the patients had only indirect contact with the spilled culture, probably contact with contaminated fomites. Another of the patients developed a clinical remission before treatment with antibiotics and relapsed after six months. This patient also had a positive bone marrow culture when blood cultures were negative. The type of antibody response persisting in the sera of convalescents was studied by treating the sera with mercaptoethanol and rabbit antihuman IgM sera. In the patient who relapsed, IgG antibody predominated, whereas IgM persisted for over two years in the patient without relapsing disease.

Adult↗
PubMed1975

Survival of patients with untreated liver metastases from colorectal cancer.

In 105 patients with colorectal cancer, liver metastases were found at extirpation of the primary tumor. The spontaneous survival was a median of 10 months. The intraoperative clinical diagnosis of liver metastases was subsequently confirmed by autopsy in 77 patients, was uncertain in 26, and was proved wrong in two at subsequent celiotomy. The accumulative experience shows that the median survivals range from 6 to 12 months, which is considerably better than in unselected series of liver metastases.

Colonic Neoplasms↗
PubMed1975

Distribution of disaccharidases, alkaline phosphatase, and some intracellular enzymes along the human small intestine.

The longitudinal distribution of various enzymes along the human small intestine was studied by analysis of biopsies from different parts of the small intestine, obtained from 13 patients during shunt-operation for severe obesity. Alkaline phosphatase and 3 glycolytic enzyme activities studied were rather uniformly distributed along the small intestine. Acid beta-galactosidase and hetero beta-galactosidase activities were highest in the proximal small intestine with a gradual decline throughout the intestine. The activity in the distal ileum was about half of the maximum activity. Maltase, isomaltase, sucrase, and trehalase activity had a broad maximum in the proximal and middle small intestine with a rather sharp decrease in the distal ileum. Lactase activity had a more pronounced maximum in the middle intestine with a pronounced decrease towards the proximal and distal ends. The disaccharidase activities in surgical biopsies taken 5 cm distal to the ligament of Treitz were about 10% higher than in peroral biopsies taken just at the ligament.

Adult↗