Biomedical subjects

B Arnesjö

Publications and source records attributed to B Arnesjö.

At least 37 records · Page 2Linked to original sources

PubMed1976

Enterovirus infections in acute pancreatitis - a possible etiological connection.

All patients admitted with a preliminary diagnosis of acute pancreatitis during a one-year period were subjected to virus investigations. 142 patients were included in the study and of these 91 were found to have acute pancreatitis. Evidence of enteroviral infection was found in 18 of the 91 patients (19.8 per cent). From 17 of the 18 patients enterovirus was isolated from feces or urine, and in one a significant titer rise (CF-test) against Coxsackie virus B5 was found. A significant titer rise of antibodies against the virus type isolated could be demonstrated in 7 of the 17 patients. Thus in 8 cases there was obvious evidence of an acute enteroviral infection during the episode of acute pancreatitis. The etiological agents in these cases were Coxsackie viruses B2, B3, and B5, and ECHO-viruses 6, 11, 22, and 30.

Acute Disease↗

PubMed1975

Surgical injuries of the ureter. A review of 42 cases.

A review of 42 cases of iatrogenic ureteral injuries treated at the Department of Urology in Lund is presented. A thorough knowledge of the anatomy and blood supply of the ureter is necessary to avoid damage to the ureter during surgery. If, however, such injuries occur, early diagnosis is desirable. Several surgical methods are available for reconstruction. Of great importance is proper choice of the procedures to be used in a given case. The value of diverting operations (pyelostomy, nephrostomy) is stressed. Nephrectomy cannot always be avoided especially if the injury is not detected early. In order to evaluate the results of reconstructive procedures postoperative control with intravenous pyelography is recommended to enable early diagnosis of restrictures and thereby early reoperation.

Female↗

PubMed1975

Bile acid pattern of gallbladder and hepatic bile in patients with and without cholesterol gallstones.

Bile acid composition of hepatic and gallbladder bile was examined in a group of 18 patients with uncomplicated cholelithiasis and a control group consisting of 13 patients with healed duodenal ulcers. Bile specimens were taken during laparotomy. Molar concentrations of the different bile acids in hepatic and gallbladder bile were determined. The ratios between the molar concentrations of the different bile acids were calculated. In order to compare these molar ratios in hepatic and gallbladder bile the quotients between identical molar ratios of hepatic and gallbladder bile were calculated in each subject. Bile acid concentration of the gallbladder bile was found to be lower in the gallstone patients. Trihydroxy or dihydroxy bile acid molar ratio was lower in the gallstone group. Hepatic to gallbladder relative trihydroxy to dihydroxy and cholate to deoxycholate bile acid ratios were elevated in the gallstone patients. This might indicate that an increased formation of deoxycholate is the main cause for the decreased trihydroxy to dihydroxy bile acid molar ratio observed in the gallbladder bile of patients with cholesterol gallstones.

Adult↗

PubMed1975

Pancreatico-jejunostomy in chronic pancreatitis. An appraisal of 29 cases.

Pancreatico-jejunostomy end to side after resection of the pancreatic tail, or side to side following longitudinal cleaving of the pancreatic duct, was performed in 29 patients suffering from chronic relapsing or acute recurring pancreatitis. A follow-up study with observation time ranging from 6 months to 10 years is presented. The patients were allotted to three groups according to the severity and extent of the inflammatory involvement at operation. The diagnostic findings obtained at the preoperative evaluation correlated well to these groupings. In some patients, however, the inflammatory process was mainly confined to the ductal system, as revealed by pancreatography, while in others the changes were most marked in the parenchyma, as found at histologic examination. 21 caudal pancreatico-jejunostomies and 8 longitudinal anastomoses were performed. Overall results were excellent in 20 patients, good in 6, fair in 3, and poor in none. The rate of postoperative complications was low; no mortality, one spontaneously healed anastomosis insufficiency, subphrenic abscess developed in 2 instances and postoperative diabetes in 5. Only one patient had a recurrent attack of acute pancreatitis postoperatively. Re-anastomosis was successfully performed.

Acute Disease↗

PubMed1975

The effect of peritoneal lavage on the postoperative course after colonic anastomosis and perforation in the rat.

Peritoneal lavage was given during four days to rats subjected either to transection and re-anastomosis or perforation of the descending part of the colon or caecum. Control rats were treated in the smae way but did not receive peritoneal lavage. The rats which were treated with a colonic anastomosis and peritoneal lavage had significantly less abdominal adhesions, peritonitis and peritoneal fluid observed at autopsy 11 or 60 days after surgery. No rats developed anastomosis insufficiency and all survived. Peritoneal lavage in rats subjected to colonic or caecal perforation increased the survival time and reduced the mortality rate, the frequency of adhesions and the signs of peritonitis. An increased frequency of peritoneal adhesions was observed after extensive mobilization of the colon during operation when no peritoneal lavage had been given. The peritoneal lavage catheter per se did not cause adhesions.

Animals↗

PubMed1975

Spontaneous rupture of the liver.

Four cases of spontaneous rupture of the liver are reported. In all these cases, pathological processes in the liver caused the rupture, i.e. primary hepatoma in 3 cases and a benign angiomatous tumour in one case. In one case, the diagnosis was not established until autopsy and in 3 cases at operation. In one of these latter cases, however, the bleeding source was not found until at a secondary surgical exploration. In none of the patients was the diagnosis suspected preoperatively. Four-quadrant puncture is highly recommended even in patients with only a slight suspicion of intra-abdominal hemorrhage. In cases with a ruptured solitary primary liver tumour, an acute liver resection might be performed. If there are multiple tumours--primary or secondary--simple hemostasis seems to be the treatment of choice. In patients with intra-abdominal hemorrhage, thorough palpation of the whole liver is an obligatory manovre during surgery.

Aged↗

PubMed1975

Studies on the reversibility of oral trypsin inhibitor induced changes of rat pancreatic exocrine enzyme activity and insulin secretory capacity.

Rats were given a daily dose of bovine trypsin inhibitor for 3 weeks (Group 3 A) or 8 weeks (Group 8 A) via an orogastric tube. In another rat group the trypsin inhibitor after 3 weeks was replaced by water for another 5 weeks (Group 8 B). In group 3 A and 8 A an enlargement of the pancreatic gland was found. In group 3 A and 8A the pancreatic protein was increased. In group 3 A and 8 A the pancreatic trypsinogen increased in a more pronounced way than the amylase, while the pancreatic lipase was found to be uninfluenced by the trypsin inhibitor treatment. Five weeks after the cessation of a 3-week treatment the only remaining effect on the exocrine pancreas was an increase of the pancreatic trypsinogen. In group 3A an impairment of insulin secretion following intravenous L-isopropylnoradrenaline and glibenclamide was found. Glucose levels were similar to those of the control rats. Furthermore, a slight decrease of the pancreatic insulin content per g protein was found in these rats. In group 8A and 8B, the insulin secretory pattern was found to be normal following intravenous glucose administration, and an increased glucose elimination rate (k-value) compared with the control group suggested a favourable effect of oral trypsin inhibitor treatment on the glucose tolerance,

Administration, Oral↗

PubMed1974