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Biomedical subjects

B Blaive

Publications and source records attributed to B Blaive.

At least 73 records · Page 4Linked to original sources
PubMed1980

[Aneurysm of the arteria lusoria. Clinical and diagnostic aspects. Postoperative results after resection and restoration of arterial continuity].

A 55 year old man, hypothyroid from previous thyroidectomy, presented with angina due to tracheal compression by a tumour of the posterior superior mediastinum. The preoperative work-up was negative. An aneurysm of a retrooesophageal subclavian artery was found at exploratory right thoracotomy in January 1977. This was resected and arterial reconstruction with a dacron graft was performed. The long term post operative clinical and angiographic results are satisfactory. The medical literature of this rare condition is reviewed.

Aneurysm↗
PubMed1979

[Clinical value of the determination of carcinoembryonic antigen in bronchial secretion (author's transl)].

Determination of carcinoembryonic antigen (CEA) by radioimmunoassay was performed in per-endoscopic obtained bronchial secretion. Bronchial CEA values are higher in the case of primary carcinoma of the lung than of metastatic lung cancer or pulmonary benign disease (p less than 0.0005). More interesting is the ratio bronchial CEA/serum CEA which is much higher in primary carcinoma of the lung than in benign disease (p less than 0.0005) and lower in metastatic lung carcinoma than benign disease (p less than 0.0025). In primary carcinoma of the lung, the CEA determination seems to have a prognostic value since higher levels are reported in patients unsuccessfully treated than in treated patients with apparent remission.

Bronchi↗
PubMed1979

[Pulmonary mycobacteriosis due to Mycobacterium chelonei: a report on a new case (authors' transl)].

Mycobacterium chelonei is a saprophytic germ usually devoid of pathogenic activity. Over a period of about the last ten years, however, several cases have been reported, including twelve cases of bronchopulmonary affections, in which it has been the infecting organism. The radiographic appearance is in every respect similar to that observed in pulmonary tuberculosis. A positive diagnosis of infection due to this germ can be made by the absence of Kuch's bacillus the lack of therapeutic effect of antituberculous medication, a positive skin reaction to specific antigens, and positive Mycobacterium Chelonei cultures from biopsy specimens. A new case of this infection is reported.

Humans↗
PubMedDate not supplied

[Comparative clinical evaluation of two mucolytic agents: S-carboxy-methyl-cysteine and letosteine (author's transl)].

A controlled double-blind clinical trial comparing a noval medicament, letosteine, to a known bronchial fluidifier, S-carboxy-methyl-cysteine, was conducted on a total of 47 hospitalized patients suffering from various types of chronic obstructive lung disease. Daily observations were made on the patients themselves and on sputum samples obtained from them before, during and after the course of mucolytic therapy. When the code was broken at the end of the trial, there appeared no significant difference between the patient groups treated with the two drugs regarding either changes in respiratory symptoms or changes in sputum characteristics. Thus, in this study, letosteine (50 mg t.i.d.) appeared equivalent to S-carboxy-methyl-cysteine (750 mg t.i.d.) in the treatment of chronic obstructive lung disease in adults.

Aged↗
PubMedDate not supplied

[Comparative in vitro and in vivo study of several long-acting theophyllines].

This study describes the comparative in vitro and in vivo release of six slow-release formulations. In vitro, with half-change method, differences appear in the profiles, some formulations showing a linear release (Dilatrane, Euphylline LA, Théostat), the others an irregular release with 'plateau' related to the pH gradient (Armophylline, Cétraphylline, Théolair). In vivo, at steady state, the fluctuations are less important and the comparative kinetic study in ten normal healthy volunteers after chronic oral dosing of six different formulations show a slight variability in the theophylline release during 12 h. Great interindividual variations appear with all formulations. In fact, none of the formulations present an ideal release over a 12 h period.

Adult↗