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Biomedical subjects

B C Deb

Publications and source records attributed to B C Deb.

At least 37 records · Page 2Linked to original sources
PubMed1986

Studies on interventions to prevent eltor cholera transmission in urban slums.

Transmission of eltor cholera infection in endemic communities continues without diminishing because of the absence of effective intervention measures. Two methods-chlorination of stored water and the use of a narrow-necked earthenware vessel (called a 'sorai') for storing the water-were found to be effective in reducing the transmission of infection among the family contacts of cholera patients. The cholera carrier rates in the chlorination and 'sorai' intervention groups were 7.3% and 4.4%, respectively, compared with 17.3% in the control group. The 'sorai' is cheap and was well accepted by the local communities; its narrow neck prevented the introduction of the hand and contamination of the stored water.

Adolescent↗
PubMed1982

Kanagawa phenomenon and serotypic pattern of Vibrio parahaemolyticus strains isolated from various sources in Calcutta.

A total of 135 strains of Vibrio parahaemolyticus isolated during the period 1976-77 from human gastroenteritis cases and various categories of environmental sources, e.g., crustaceans, fish and different water samples (pond, stored, open well and tap water) were tested for their Kanagawa phenomenon and serotypic pattern. Amongst the 80 human isolates tested, 69 strains (86.3%) were Kanagawa phenomenon positive, and 60 strains (75.0%) were serologically typable--the dominant serotype being 05:K15. Of the 25 isolates from various water sources 10(40.0%) were Kanagawa phenomenon positive, and 17(68.0%) were serologically typable and 4 (23.5%) of them belonged to serotype 05:K15. All the 30 strains isolated from crustaceans and fish were Kanagawa phenomenon negative and 22 (73.3%) of them were serologically typable, belonging to heterogeneous serotypes. The results of this study also indicate the possible role of water in the transmission of V. parahaemolyticus infection in Calcutta slums.

Food Microbiology↗
PubMed1981

An epidemic of rotavirus diarrhoea in Manipur, India.

Recurrent epidemics of acute diarrhoeal disease in young children have occurred during the winter months in Manipur (India) for many years. During November 1979, children admitted to hospital for acute diarrhoea were investigated and, in addition to pathogenic Escherichia coli and Shigella rotovirus was detected by ELISA in a number of stool samples, especially of those less than one year old. The importance of this finding and the need for further study are discussed.

Diarrhea, Infantile↗
PubMed1980

A controlled field trial of an aluminum phosphate-adsorbed cholera vaccine in Calcutta.

A controlled field trial to determine the efficacy of a single dose of an aluminium phosphate-adsorbed cholera vaccine was conducted in Calcutta during 1975-77. An aluminium phosphate-adsorbed tetanus toxoid was used as the placebo. Follow-up of the immunized volunteers for a period of two years showed that the adsorbed cholera vaccine provided 100% protection to children under five years of age for 6 months, 88.9% for 12 months, and 91.7% for 18 months (P<0.05). The overall protection for all age groups was 58.5% for 18 months. There were no serious side effects following the anti-cholera inoculations.

Adjuvants, Immunologic↗
PubMed1978

Effect of doxycycline on transmission of Vibrio cholerae infection among family contacts of cholera patients in Calcutta.

Doxycycline was used among the family contacts of hospitalized cholera patients in Calcutta to determine its effectiveness in controlling transmission of V. cholerae infection. A total of 137 such contacts were given a single oral dose of doxycycline in graded doses according to age. A similar group of 139 contacts received a single dose of multivitamins as placebo. All 276 contacts were examined bacteriologically daily for 10 days for the presence of V. cholerae in their stools. The results showed that doxycycline was effective in significantly reducing the load of V. cholerae infection for up to 5 days following treatment.

Adolescent↗
PubMed1976

Effect of sulfadoxine on transmission of Vibrio cholerae infection among family contacts of cholera patients in Calcutta.

Sulfadoxine, a long-acting sulfonamide, and tetracycline were compared as regards their effectiveness in reducing transmission of cholera infection among the contacts of cholera patients in Calcutta. A total of 109 healthy family contacts of confirmed hospitalized cholera patients were treated with a single oral dose of sulfadoxine graded according to age. Another similar group of 101 contacts received 6 divided doses of oral tetracycline over a period of 3 days. All these contacts were bacteriologically examined for 15 days. Results showed that tetracycline was effective in significantly reducing the load of cholera infection from the 2nd to 6th day, while sulfadoxine was effective from the 3rd to the 6th day. The advantages and disadvantages of the two drugs as chemoprophylactic agents in cholera are discussed.

Administration, Oral↗