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B Carpenter

Publications and source records attributed to B Carpenter.

At least 37 records · Page 2Linked to original sources
PubMed1997

Comparison of African-American and white persons with Alzheimer's disease on language measures.

We assessed 11 African-American and 32 white subjects with early to midstage AD using seven measures (the Boston Naming Test, Peabody Picture Vocabulary Test-Revised, Shortened Token Test, a modified Reporter's Test, two subtests of a shortened Rey Auditory Verbal Learning Test, and selected stimuli from the Test of Problem Solving). There were no ethnic differences, with Mini-Mental State Examination score and education accounting for most of the variance between ethnic groups. However, white subjects tended to score higher than African-Americans on five of the seven measures. African-Americans tended to perform better on the Test of Problem Solving, a measure of the pragmatic use of language. Although these preliminary findings suggest no test bias for ethnicity, the trends indicate that language measures should continue to be examined for ethnic differences in larger samples.

Black or African American↗
PubMed1995

Who cares for Peter?

Explore the source record for details and available documents.

Health Services Needs and Demand↗
PubMed1995

Parosteal fasciitis in children.

Parosteal fasciitis is a pseudosarcomatous benign lesion of fibrous tissue that has often been confused with malignancy. The purpose of this study was to document the clinical and pathological features of four children with this condition and compare the results with the world literature. The ages of the patients whose cases were reviewed ranged from 9 to 15 years. There were three girls and one boy. All the lesions occurred in the lower extremities, and histologically were characterized by a fibroblastic proliferation with inflammatory cells, diffuse capillary network, and varying quantities of metaplastic bone. All patients were treated by local excision of the lesion. One child had a recurrence of the lesion requiring another surgical removal. A set of clinicopathological criteria has been formulated for the diagnosis of parosteal fasciitis in children. Parosteal fasciitis is uncommon in children but manifests the same clinicopathological features as the adult lesion.

Adolescent↗
PubMed1995

Primary carcinoid of the prostate in conjunction with multiple endocrine neoplasia IIb in a child.

Prostatic neoplasms are rare in childhood. We report a case of primary prostatic carcinoid in a 7-year-old boy who was subsequently diagnosed with multiple endocrine neoplasia IIb. To our knowledge this is the first report of either pediatric carcinoid of the prostate or of prostatic carcinoid in conjunction with neuronal intestinal dysplasia and medullary thyroid carcinoma suggestive of multiple endocrine neoplasia IIb. Management and histogenesis regarding this prostatic tumor are discussed as is a possible association with other neuroendocrine tumors.

Carcinoid Tumor↗
PubMed1993

Fibromatosis in infancy and childhood: the spectrum.

Fibromatoses form an interesting group of tumors occupying a midposition in the spectrum of fibrous tissue neoplasms. Within the fibromatoses subgroups there exists a variety of tumors whose clinical behavior spans the range from completely benign to locally aggressive. Four case histories are presented to illustrate this point. All four patients were initially seen with asymptomatic head or neck masses. The first had complete excision with no recurrence to date. The second underwent spontaneous regression after confirmation of diagnosis with biopsy. The third case had a very locally aggressive disease requiring three surgical resections to date, while the last case had one recurrence after the initial resection. With certain exceptions, initial wide local excision offers the best possible chance for cure.

Biopsy↗
PubMed1991

A new model of nephrolithiasis involving tubular dysfunction/injury.

To better understand the pathogenesis of nephrolithiasis, we developed a new animal model that closely mimics human calcium oxalate stone disease. Rats were treated with a regimen that combines moderate hyperoxaluria (produced by 10 days of feeding with 3% ammonium oxalate) with mild proximal tubular injury/dysfunction (produced by 8 daily injections of gentamicin sulfate -40 mg./kg.). This combined treatment caused a marked increase in the incidence of calcium oxalate crystals and stones over that seen in animals treated with oxalate or gentamicin alone. Using a semiquantitative scoring system for estimating the abundance of crystals in coronal sections of kidneys, we found that 63% of animals receiving gentamicin plus oxalate showed "moderate" numbers of crystal, as compared to 8% of animals receiving oxalate alone; and the majority of the crystals occurred in the papilla, a pattern similar to that seen in human stone disease. Untreated rats and rats treated with gentamicin alone did not exhibit calcium oxalate crystals or stones. Despite the abundance of crystals and stones, animals receiving gentamicin plus oxalate retained relatively normal renal function as judged by creatinine clearance. Thus, the model has several advantages over preexisting models of nephrolithiasis. Crystal and stone deposition develop rapidly (within 14 days). The pattern of deposition resembles that seen in human stone disease and renal function remains relatively normal. These findings indicate that this model of nephrolithiasis may prove useful for studies of the pathogenesis of stone disease. Moreover, they suggest that renal tubular injury and/or dysfunction may produce conditions conducive to the formation and growth of calcium oxalate stones.

Animals↗
PubMed1991

Oxalate transport in renal tubular cells from normal and stone-forming animals.

To investigate the cellular mechanism(s) underlying kidney stone disease, we examined oxalate uptake in suspensions of renal cortical and papillary cells derived from control and stone-forming animals. In control animals, both cortical and papillary cells exhibited a time-dependent accumulation of oxalate. This uptake was mediated both by passive diffusion and by one or more transport processes sensitive to the anion transport inhibitor, DIDS. Oxalate uptake was also markedly sensitive to extracellular pH, showing increased uptake at acidic pH outside (pHo) (6.0), and reduced uptake at alkaline pHo (8.0). In renal tubular cells from stone-forming animals, oxalate uptake was markedly altered. Uptake was significantly reduced in cortical cells, whereas it was significantly stimulated in papillary cells from the same animals. Since the observed changes in oxalate handling occurred only in stone-forming animals, it is possible that alterations in renal cell oxalate transport contribute to calcium oxalate stone formation.

4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid↗
PubMed1990

An unusual intraoral mass in a child: the organ of Chievitz.

A 5-year-old girl presented with a hard, asymptomatic, fixed mass protruding intraorally at the level of the ascending ramus of the mandible on the right. Plain roentgenograms of the jaw, panorex, computed tomography scan, and magnetic resonance scan of the area failed to demonstrate any lesion. An incisional biopsy showed neuroectodermal tissue with a pattern characteristic of the juxtaoral organ of Chievitz. At 2 years follow-up, the residual mass remains the same. The organ of Chievitz is a normal structure that can be frequently identified at routine autopsy if sought for, but is seldom large enough to present as a mass. A conservative biopsy without further treatment is recommended when the clinical diagnosis is in doubt.

Cheek↗
PubMed1989

Definitive treatment of focal nodular hyperplasia of the liver by ethanol embolization.

Focal nodular hyperplasia (FNH) is a benign, usually asymptomatic liver tumor with no predisposition to spontaneous hemorrhage. Treatment is not mandatory unless large size, compression symptoms, or fear of traumatic hemorrhage indicate otherwise. Ethanol embolotherapy offers a safe and effective alternative to surgery. FNH lends itself particularly well to embolotherapy because it is usually fed by a single end-artery with no intratumoral arteriovenous shunting or parasitic blood supply. An illustrative case is presented. Diagnosis was established by ultrasound, computed tomography (CT) scan, radionuclide scan, and arteriography and was confirmed by biopsy. Ethanol embolization resulted in shrinkage of a 10 x 14 cm tumor to a 1.5-cm calcified nodule over an 18-month period.

Adolescent↗
PubMed1989

A new method for demonstrating argyrophil cells of the pancreas and intestines.

A new method for demonstrating argyrophil cells of the pancreas and intestinal tract using a combined silver and reducing solution in sections of formaldehyde fixed tissue is described. Impregnating sections in a 60 C water bath, the procedure takes about 25 min. A microwave version that takes about 5 min is also given. Results are similar to those obtained with the Grimelius method for argyrophil cells.

Formaldehyde↗
PubMed1989

Pseudoclubbing in chronic renal failure.

Seven patients with chronic renal failure developed a peculiar abnormality of the fingers referred to as pseudoclubbing. All had radiological evidence of severe secondary hyperparathyroidism and elevated parathormone levels measured by C-terminal assay. Treatment with vitamin D and calcium, parathyroidectomy or renal transplantation resulted in radiological healing but the deformity of the finger tips did not improve. Although these patients represent a group with severe secondary hyperparathyroidism, autonomous secretion of parathormone is not a necessary accompaniment of this disorder.

Adult↗
PubMed1987

Extraspinal ependymoma.

Two cases of extraspinal ependymoma are described. This is a low-grade tumor that recurs locally unless wide local excision is performed. It does metastasize, mainly to lymph nodes and lung. Its origin is likely from heterotopic ependymal cells called the coccygeal medullary vestige.

Adolescent↗