[4-acetamido-phenyl-2-acetoxy-benzoate (Benorylate) in the treatment of rheumatoid arthritis].
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Biomedical subjects
Publications and source records attributed to B Colombo.
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The actual hypothesis on the etiology and pathogenesis of neonatal hepatitis, intrahepatic and extrahepatic biliary atresia and choledocal cyst is that these disorders can be different results or permissible outcomes of a single basic process: infantile obstructive cholangiopathy. This hypothesis can explain the failure of many infants with operable extrahepatic biliary atresia to do well following surgically successful anastomosis. Very possibly no surgical mode of therapy will cure a significant fraction of infants with biliary atresia (correctable and non-correctable types) because the basic disease process actually produces portal fibrosis and destroys intrahepatic bile ducts as well. However, since the obliterative process can resolve, even if not usually completely, surgical procedures of conventional or of hepatic-portoenterostomy type should be considered for all infants who are found to have biliary atresia. Probably biliary atresia is more in need of preventive or prophylactic measures than of new surgical procedures.
The authors describe one case of urticaria pigmentosa in childhood as contribution to the knowledge of this disease prevalently interesting the paediatric dermatology.
The rectal sensitivity test evaluates the distension volume for which the initial transient sensation occurs on defecation (conscious rectal sensitivity threshold). The conscious rectal sensitivity threshold (S.S.R.C.) was performed on 10 normal controlled subjects and 103 children with chronic constipation, functional megarectum and normal rectoanal inhibitory reflex. Children were between 5 and 14 years old. S.S.R.C. was increased in children with chronic constipation. Encopresis was proportionally increased with relation to S.S.R.C. increase. A therapeutical protocol was applied in all patients. Fifteen patients are still being treated: 87 obtained a normal function within 8 to 23 months of treatment; in one case the treatment was unsuccessful. The period of treatment was proportional to S.S.R.C. increase. Physiopathological background of a correct management is discussed.
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Two new cases of Robert's Syndrome (R.S.) are presented. Both clinic and cytogenetic aspects of R.S. are rapidly reviewed. The significance of cytogenetic findings in R.S. is discussed.
Ureterocele is an infrequent urinary malformation in pediatric age, but it is frequently clinically severe. Ureterocele in a duplex pyelo-ureteral system often presents very difficult treatment problems not uniformly dealt with. Authors report their experience with 79 ureteroceles observed in 72 children. 27 children were less than one year old. In the authors experience simple ureterocele with a single collecting system doesn't give any surgical problem. On the contrary ectopic ureterocele, almost always associated with a pyeloureteral duplication, frequently gives some problems of surgical treatment. Treatment is always individualized but in our experience the best results have been achieved with unroofing of the ureterocele and upper heminephroureterectomy in one stage, eventually associated with lower ureteral reimplantation. This treatment can be used successfully in the majority of ectopic ureteroceles in pediatric age.
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It is essential when deciding on the therapeutic approach to the rheumatoid knee--medical or surgical--to make a precise and thorough assessment of the joint situation as a whole. In order to overcome the limitations of traditional X-ray methods, the Authors used computerized axial tomography (C.A.T.) to study the knees of twenty rheumatoid arthritis patients. They analysed three particular sections: the first at the level of the subquadriceps bursa, the second through the femoral condyles, and the third through the proximal tibio-fibular joint. C.A.T. permits an assessment of the conditions of the muscles and any hypertrophy of the synovial membrane; this kind of investigation reveals them clearly. It was possible to make an accurate investigation of the femoro-patellar joint and of lesions involving the femoral condyles and tibial plate. The findings indicate that C.A.T. in the study of the rheumatoid knee provides information on the soft tissues that cannot be obtained by traditional radiological methods. It also shows with greater precision the extent and morphology of bone lesions to the joint heads, an extremely important question in planning the use of prostheses.
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