[New anti-inflammatory agents in the therapy of chronic rheumatism].
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Biomedical subjects
Publications and source records attributed to B Colombo.
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"[Many] illiterate women, particularly in the third world, find [it] difficult to apply usual calendar methods for the regulation of fertility. Some of them are even unable to make simple subtractions. In this paper we are therefore trying to evaluate the applicability and the efficiency of an extremely simple rule which entails only [the ability to count] a number of days, and always the same way." (SUMMARY IN ITA)
The authors present a case of Meyer disease. The knowledge of this pathology, emerging from the ultrasonic screening of the hip, is useful to the pediatrician in the differential diagnostic argument.
While the cholelithiasis is very common among chronic hemolytic anemia, it is not in acute. A case of cholelithiasis as a complication of autoimmune acute hemolytic anemia in a 5 years old child is reported. A specific and accurate diagnosis was readily made with grey-scale ultrasound. Serial sonograms were obtained to follow the resolution of this case.
The authors describe a rare case of primary intestinal lymphangiectasis resolved with surgical treatment. Usually the natural course of the disease is relatively mild and medical nutritional treatment can be sufficient. In this case the lymphatic intestinal anomaly was generalized to the entire small intestine but a distal ileal segment was particularly involved. The surgical resection of this intestinal tract resolved the symptomatology.
Information obtained from the study of immunoglobulin (Ig) gene rearrangement in different types of lymphoproliferative disorders has led to the suggestion that Ig gene activation obeys a precise hierarchy in which heavy-chain gene rearrangement procedes light-chain gene recombination. However no information is available on the mechanism(s) controlling this sequential activation. We report here a case of CLL which suggests that the expression of the heavy-chain genes is not necessary for light-chain gene rearrangement, or that very low amounts of heavy-chain mRNA and/or heavy chains are sufficient to activate k-chain genes.
Hydronephrosis in infancy and childhood is a frequent urinary malformation and is almost always congenital. In over 80% of the cases it is due to ureteropelvic junction obstruction; in about 17%, anomalous renal vessels at the ureteropelvic junction are present. The authors analyze their experience in the surgical treatment of hydronephrosis. 360 hydronephrosis out of 335 patients were operated on from November 1971 to November 1988. 108 patients were less than 1 year old (32.2%). Primary nephrectomy was carried out only in 11 of the 360 hydronephrosis operated on (about 3%). An anterior approach and a simple dismembering pyeloplasty were performed in the majority of the cases. From the radiological point of view there was an impressive amelioration or normalization in about 92% of the cases operated on. From the functional point of view the radionuclide scan showed a normal or slightly reduced renal function in almost 90% of the cases operated on. The preoperative and postoperative radionuclide study showed a moderate increase of the renal function in the majority of the cases controlled. The authors stress the importance of prenatal ultrasound diagnosis to improve long term results of an early surgical treatment.
We report a case of an infant with a post-necrotizing enterocolitis stenosis, resolved with operative measures. The histologic finding of Cytomegalovirus in the resected sigmoid colon rise the question if the intestinal stricture was the proper consequence of a primary enteric viral infection or a superinfection in a transitory immunodeficiency after the acute phase of necrotizing enterocolitis.