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Biomedical subjects

B Günther

Publications and source records attributed to B Günther.

At least 109 records · Page 6Linked to original sources
PubMed1978

[Substrate metabolism of muscles during the early postoperative period: the effect of glucose infusions].

Muscle substrate metabolism was studied by measuring arterial deep-venous substrate concentration differences across the forearm in metabolically healthy volunteers 3 h after abdominal surgery. Despite elevation of insulin levels following glucose infusion, no effect on muscular fractional extraction of glucose and no decrease of lactate and alanine production was found, whereas muscular lipolysis was inhibited to a normal extent and ketone utilization was reduced.

Abdomen↗
PubMed1977

[Cryptogenic liver abscess (author's transl)].

The successful treatment of two patients with cryptogenic liver abscess, a special type of pyogenic abscess, is reported. Quick diagnosis by methods which do not distress the patient, e. g. scintigraphy and echography, leads to a decisive improvement in the prognosis. Opinions are given on the differential diagnosis of cryptogenic, pyogenic and parasitic (amebic) liver abscesses. The good chances for treatment of cryptogenic abscesses compared with the secondary pyogenic liver abscesses are to be found not least in their usually solitary appearance. This is shown particularly clearly in the classification of the patients operated on for pyogenic liver abscess in our hospital in the last ten years into multiple and solitary liver abscess. As in the pyogenic abscess, so in the primary cyptogenic liver abscess is transperitoneal open drainage the method of choice for treatment.

Diagnosis, Differential↗
PubMed1976

[Attentions, sensumotoric coordination, and angular acceleration threshold under the influence of small doses of alcohol in relation to aspects of personality (author's transl)].

In a parallel cross-over design 22 male students were examined with 0,6 g alcohol per kg of body weight (0,5 o/oo). The dependent variables were attention, sensumotoric coordination angular acceleration threshold, and mood. A number of personality trait factors (FPI, MPI, habit of alcohol and tobacco consumption, body measures) and state factors (subjective state, psychophysiological state) were also measured, others were helf constant (age, sec, intelligence, standardisized breakfest, duration of drinking time, day time, week time). The accelerated concentration of blood alcohol was connected with neuroticism and subjective bad state on day of examination. The accelerated elimination of blood alcohol varried with bad subjective state. Attention, and sensumotoric coordination were significantly (by a BAC of 0,42 o/oo) diminished and the sensitivity of angular acceleration threshold was strongly (by a BAC of 0,30, 0,44, 0,38 and 0,21 o/oo) diminished, connected with a general brightening of mood. Certain personality traits and states may diminish performances with those slight doses of alcohol.

Acceleration↗
PubMed1975

Dimensional analysis and theory of biological similarity.

From this review we conclude the following: 1) The body weight of an organism is an adequate reference index for the correlation of morphological and physiological characteristics. In comparative physiology, body weight can be recommended as a unifying frame of reference, particularly if the ponderal scale includes several decades, in order to apply logarithmic scales for the variables involved. (See article). 2) The statistical analysis of the experimental data can be represented conveniently by means of the logarithmic equivalent of Huxley's allometric equation (y = a-Wb), which is the most simple and at the same time the most versatile mathematical expression for intra- or interspecies comparisons. The exponents (b) for the allometric equations can be predicted for all biological variables definable in terms of the MLT system of physics (M = mass, L = length, T = time) or of a four-dimensional system MLTt where t = temperature. 3) By means of dimensional analysis and the theory of biological similarity a range of similarity criteria can be established: a) mechanical or dynamic similarity, b) kinematic or biological similarity; and c) hydrodynamic or transport similarity. Most functions obey the so-called biological (kinematic) similarity, particularly when the concept of operational time is introduced into Lambert-Teissier's original theory. 4) A satisfactory correlation (r = 0.99) for 80 empirical allometric exponents (b) describing morphological and physiological characteristics of living beings was found. These results are discussed in relation to Rosen's optimality principles in biology. 5) Organisms should be considered as mixed regimes. This means that no single similarity criterion can predict the allometric exponent (b) of all functions that dimensionally belong to MLT or MLTt systems, despite the fact that in the great majority of cases kinematic similarity will satisfactorily predict the reduced exponent (b). Nevertheless, in some instances mechanical (dynamic) similarity must be applied, and in other circumstances hydrodynamic (transport) similarity. 6) Cellular or molecular levels are not in the domain of the present theory, since neither cell dimensions nor molecular processes (viz., blood viscosity, diffusion capacity) can be predicted by biological similarity criteria.

Amphibians↗