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Biomedical subjects

B M Anokhin

Publications and source records attributed to B M Anokhin.

At least 19 recordsLinked to original sources
PubMed1993

[Value of rapid biopsy in diagnosis of thyroid cancer].

Patients with thyroid carcinoma (ThC) in 67% are erroneously operated on with the diagnosis of nodular struma, this resulting in the recurrences in 30% and mortality and complications reaching 42%. Since 1977 the authors were performing rapid biopsies in all cases of the euthyroid struma and this resulted in the proper diagnosis in 98% of operated patients (48.6% before this). Short-term examination consists of stereo-morphology of the surgical material and the preparation by means of the deep frozen knife, of the histo-topographical section stained by Harris hematoxylin. Microcarcinomas are revealed by this method 30 times more frequently than in routinely treated sections. Short-term biopsy of the thyroid is as necessary as it is in the mammary gland lesions.

Biopsy↗
PubMed1989

[Ultrasonic tomography in the diagnosis of diseases of the thyroid gland].

The paper deals with the characteristics of application of microwave computed tomography in diagnosis of most frequent tumors of the thyroid gland in 146 surgical cases. The role and scope of microwave studies carried out in dynamic monitoring thyroid cancer patients to assure early detection of metastasis and recurrence are discussed.

Adenocarcinoma↗
PubMed1982

[Medullary cancer of the thyroid].

The paper deals with a study of 42 cases of medullary carcinoma which accounts for 12.6% of all forms of thyroid cancer. The female-to-male ratio was 1.3:1, mean age - 45 years. Medullary carcinoma occurs sporadically in cases of familial endocrine syndrome. A case of Sipple's syndrome is reported. Medullar carcinoma is a hormonally-active tumor which produces calcitonin, the latter serving as a tumor marker for this carcinoma. Medullary carcinoma is characterized by bilateral involvement of the thyroid, which is more frequent in cases of familial disease, and a high rate of incidence of regional metastases (82.5%). Apart from clinical diagnostic means, the disease is chiefly identified cytologically and by calcitonin assays in blood plasma. It is mainly treated by surgery; 5- and 10-year survival rates are 87.2 and 80%, respectively.

Adult↗
PubMed1978

[Method of preparation and staining of microscopic sections in emergency biopsy].

To obtain a distinct and sufficiently standard staining of sections in urgent biopsy Harris hematoxylin should be used the preparation of which is based on oxidation of aluminous hematoxylin by mercuric oxide. This solution stains nuclei of the preparations quite rapidly (within 1/2-1 min) and very electively. The use of a fan for drying of sections on slides and other devices described by the author shorten the time of express biopsy preparation to 5-7 minutes.

Biopsy↗
PubMed1978

[Immunomorphological transformation of the thyroid gland in autoimmune thyroiditis].

In parallel immunochemical, immunohistochemical, and histopathological studies of blood sera and biopsies of the thyroid gland tissue the autoimmune nature of thyroiditis was proved in 11 female patients. The detected antithyroid autoantibody was classified as complement-dependent immunoglobulin. Immunocytochemical data are presented confirming the histiocytic derivation of macrophages and non-epithelial nature of B- and C-cells. Transformation of colloid and cells ans metabollsm of monoclonal immunoglobulins (IgG, IgA, IgM) permit the judgement on the duration of autoimmune thyroiditis. The diffuse lymphoid variant is typical of the first 5 years, and focal fibrinolymphoid variant-for later peroids of autoimmune thyroiditis.

Adult↗