[Recurrent focal vulvar melanoma 6 years after surgical treatment].
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Biomedical subjects
Publications and source records attributed to B Musiatowicz.
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The authors report histological and clinical analysis of 7 patients with malignant proliferation of the stromal colls in the endometrium. In 3 patients the histological pattern differed form that in the remaining cases in a greater number of cell divisions and higher grade of cell atypia. Despite this, the clinical pattern was similar in nearly all cases. The reported material cannot support the hypothesis of two forms of the disease: stromal sarcoma and stromatosis. Both these diagnoses carry a poor prognosis.
The authors analysed 348 patients with endometrial carcinoma taking into account the diagnoses of adenocarcinoma, adenoacanthoma and mixed carcinoma. In evaluating these patients the degree of histological malignancy, extent of malignant infiltration in the uterus were considered, development of endometrial carcinoma in different phases of life of the women was studied, the hormonal profile and the methods of treatment were analysed. It is stressed that the prognosis of mixed carcinoma is worse than that of adenoacanthoma.
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The effect of Listeria monocytogenes lipids (Lm lipids) on immunity against Candida albicans, Cryptococcus neoformans and Trichomonas vaginalis was studied in mice. The administration of Lm lipids did not affect significantly the course of T. vaginalis infection. On the other hand, single Lm lipids injection markedly decreased the mortality rate of mice with mycotic infections, and significantly accelerated the elimination of fungal cells from liver, spleen and blood circulation of animals. It is suggested that enhanced resistance of mice conferred by Lm lipids may be related to observed increase in activity of macrophages. The study demonstrated a very low toxicity of Lm lipids preparation.
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