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Biomedical subjects

B N Varava

Publications and source records attributed to B N Varava.

At least 37 records · Page 2Linked to original sources

[Role of ultrasonic echo location in the diagnosis of nonspecific thoraco-abdominal aortoarteritis].

Ultrasonic echo-location (UEL) was used in 14 patients with nonspecific thoracoabdominal aortoarteritis before and after surgical treatment. Ultrasonic data were compared with aortographic and intraoperative findings. Patients with atherosclerosis of the abdominal aorta and congenital hypoplasia of the latter made up the control group. UEL is regarded as a fairly informative method of the diagnosis of nonspecific aortoarteritis, as thickened walls of the aorta and other affected vessels as well as irregular indurations involving aortic walls and para-aortic fat are pathognomonic signs of nonspecific aortoarteritis that differentiate it basically from other kinds of lesions. Besides, UEL is capable of early detection of the condition and the assessment of the routes of pathologic spread. After surgery, UEL might be used to control the state of the alloprosthesis.

Adolescent↗

[Morphogenesis of the intimal thickening observed in nonspecific aortoarteritis].

Thickening of blood vessel segment intima (aorta, carotid, femoral and renal arteries) excised from 9 patients during surgery for nonspecific aortoarteritis was studied, using electron microscopic autoradiography. A large number of vessels of capillary and precapillary type were found among cells and in the intracellular substance of thickened intima. Vascular endotheliocytes and pericytes were easily labelled with 3H-uridine. It is suggested that cells appear in the thickened intima due to growth of small vessels of the capillary type, covered with pericytes which turn into fibroblast-like cells producing intracellular substance, and not due to smooth muscle cell migration from the media. In addition, it was found that the lumens of some vessels were filled with fibrillar material and that the cells underlying the vessel stayed apart, not forming a continuous circle. It is suggested that the damage of normal vascular structure can also result in the appearance of free cells.

Adult↗