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B Nikolić

Publications and source records attributed to B Nikolić.

36 records · Page 2Linked to original sources

[Analysis of the results of mycological examination of skin samples from 1997 to 1998].

Mycological findings of 2,447 skin specimens were analyzed. The aim of the study was to estimate the methodology for mycological examination, frequency of particular fungal species isolation and localization on the skin. Fungi were found in 591 specimens: 53.64% microscopically and isolated in cultures, 31.47% only microscopically and 14.89% only isolated in cultures. Total number of isolated strains was 405 (356 strains grew on Sabouraud agar with antibiotics and 272 on mycobiotic agar). The most frequently isolated species were: Trichophyton mentagrophytes (27.9%), Trichophyton rubrum (20%) and Candida albicans (9.14%). The most frequent localizations on skin where fungi had been found were foot (41.47%), toe-nail (22.06%) and finger-nail (10.88%). Sabouraud agar is more reliable for isolation of dermatophytes and mycobiotic agar for Candida species. Usage of both media for primoisolation provides better and faster identification of fungi causing dermatomycoses. Comparing our with other studies, the patterns of fungal appearance in our population had changed and the number of nail specimens, where fungi were found had increased.

Culture Media↗

Experimental study of the effects of known quantities of zearalenone on swine reproduction.

Experiments were carried out in order to study the effect of known quantities of zearalenone on reproductive performance of gilts. Zearalenone was produced on autoclaved corn using pure cultures of Fusarium graminearum Schwabe (local strain of Leskovac). The amount of 22.09 mg/kg of zearalenone in the ration of breeding gilts had an obvious harmful effect on their reproductive performance decreased number of corpora lutea, decreased weight of ovaries, decreased number of live embryos, increased number of dead-born piglets, and the occurrence of abortus. These effects were less pronounced in gilts fed mashes containing 2.2 mg/kg zearalenone. However, in both groups the uterotropic effect of zearalenone was obvious.

Animals↗

[Correlation between ultrasonographic and celioscopic findings during stimulated cycles in women undergoing fertilization in vitro].

The authors emphasize the importance of ultrasonographic follow-up of the growth and development of the follicle in patients prepared for fertilization in vitro. The study concerned 30 patients in whom an appropriate stimulation was carried out. Correlation between ultrasonographic and coelioscopic findings is analysed. On the basis of the obtained results it was concluded that ultrasonographic diagnosis may be useful in the evaluation of the number, size and volume of a follicle. This method was also appropriate for the evaluation of the follicle maturity and determination of the best time for their puncture. In this was follicles that are in the most favourable time for fertilization in vitro, can be obtained.

Adult↗

[Cervical maturation using Prepidil gel in pregnancy termination in primigravidas].

The study investigated the possibility of pharmacological servical ripening induced by Dinoprostone (Prepidil Gel--Upjohn Co) prior to therapeutic abortion in primigravida. The study concerned patients-volunteers choosen by random. 73 patients were divided into two groups with the same average age, term of gestation, cervix consistency and passage through the cervical canal before the application of gel. In the first group therapeutic abortion was carried out 6 hours after the application of gle into cervical canal, and in the second group--4 hours after the gel application. Cervical maturation, testified by its consistency and spontaneous cervical ripening, was equal in both groups (average delta Hegar I was 7.32 and delta Hegar II--7.02), and it enabled medical procedure only with the local anaesthesia with 2% hylocein in 82% ob pregnant women. In a fifth of patients ob both groups it was necessary to do additional mechanical dilatation, which was easily performed due to the already soft cervix; these patients were also administered 1 ampulla ob Fortral I.V. In both groups during the action of Dinoprostone there were no significant changes either in blood pressure or in body temperature. More expressed uterine activity, followed by initial and incompleted abortions, were more frequent in patients of the first group (3529%) than in those from the second group (17.95%) in which only contractions occurred (33.33%). The rate of gastrointestinal side effects was 29.41% in the first group and 41.03% in the second group. There was no uterine complication during the activity of Dinoprostone as well as during and after medical procedure.

Abortion, Induced↗

[Contact thermometry of lesions in alopecia areata].

The contact thermometry has been performed at the center of lesions, at the periphery and at the adjoining healthy skin in 10 patients with alopecia areata (AA) of the scalp. The lowest temperature was recorded in the center of lesions (approximately 33.55 degrees C), slightly higher in the periphery (approximately 33.71 degrees C) and the highest in the adjoining healthy skin (approximately 34.01 degrees C). The authors suggest the skin temperature to be the result of the degree of vascularization. The obtained results were examined in reference to the results published elsewhere on the light and electronic microscopy of AA lesions where the changes in capillaries were found. Based on all the above, the authors consider the topical use of drugs that improve the peripheral circulation to be justified in the treatment of AA.

Adolescent↗

[Ulcus molle].

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Adult↗

[Mast cells and basophilic leukocytes in allergic inflammation].

The human mast-cell population is composed of a heterogenous group of cells with respect to structure and function. Mast-cells can no longer be regarded simply as cells that initiate acute allergic reactions through the release of rapidly metabolized mediators, such as histamine and products of arachidonic acid oxidation. The production of a wide range of cytokines by mast-cells in the centre of the allergic inflammation. These cytokines influence migration and activation of other different cells including basophils and eosinophils and also lymphocytes, thus perpetuating allergic inflammation. Mediators release from human basophils are considered to contribute to the late phase of allergic response.

Animals↗

[Angiokeratoma circumscriptum].

We have presented a 12-year-old boy with angiokeratoma circumscriptum on his left knee. The lesion first appeared at the age of eight as a dark brown nodus with the verrucous surface. It bled easily even after mild trauma this being a principal reason for the hospital admission and surgical excision in toto. Pathohistological examination confirmed the clinical diagnosis. Differential diagnosis, clinical and pathohistological findings, as well as therapy of the disease have been discussed in some detail.

Angiokeratoma↗