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Biomedical subjects

B Sandström

Publications and source records attributed to B Sandström.

At least 181 records · Page 10Linked to original sources
PubMed1980

Zinc absorption from composite meals. II. Influence of the main protein source.

The absorption of zinc in man from composite meals of conventional foods with various main protein sources was measured with a radionuclide technique. The meals were extrinsically labeled with 65Zn and the absorption of zinc was determined from a measurement of the whole-body retention of the isotope about 2 weeks after ingestion of the labeled meal. The meals consisted of a meat patty made from either chicken, beef, or soybeans, and included potatoes, tomatoes, and white bread. For meals based on animal protein a positive correlation was found between zinc absorption and zinc content. When 25% of the animal protein in the chicken meal was replaced by defatted soy flour neither the zinc content nor zinc absorption were significantly influenced. The same substitution in a beef meal resulted in a decrease in zinc content and also a lower zinc absorption. The absorption from a soybean meal did not differ from an animal protein meal with the same zinc content. Lower zinc absorption was found when the calcium content of a soybean meal was increased by the addition of milk. For this study, the total zinc content of the meal was the most important factor influencing the amount of zinc absorbed.

Adult↗
PubMed1979

A new and sensitive method for quantifying and comparing the biological potency of varius estrogens in man.

The serum level of an estrogen-inducible plasma protein was followed by a radioimmunoassay in groups of women during treatment with various estrogens. After an initial increase, the mean value for the serum concentration was stable. The plateau level after six months of treatment was taken as a parameter of estrogenic potency. Eleven different hormonal preparations were compared and an estrogen index was constructed.

Contraceptives, Oral, Sequential↗
PubMed1979

Adjustments of circulation including blood pressure to orthostatic reaction and physical exercise during application of a low estrogen dose steroid oral contraceptive.

The orthostatic circulatory reaction, the physical working capacity on a bicycle ergometer, the blood pressure reactions at rest both during and after the ergometer test, the total hemoglobin content and the heart volume in the supine position were all determined on four separate occasions in 34 nulligravidae who were taking a low estrogen dose steroid oral contraceptive consisting of 30 micrograms of ethinyl estradiol and 150 micrograms of levonorgestrel (known as Neovletta, Schering AG). These examinations were performed once prior to the commencement of this medication, and 6, 12 and 24 months thereafter. The orthostatic pulse and blood pressure reactions taken on these subjects standing upright for a period of eight minutes were pronounced up to and including the 12 month control, but decreased thereafter. Physical working capacity at a pulse rate of 170 beats per minute on the different test occasions decreased up to and including the 12 month control, but thereafter seemed to increase almost to their initial levels. Blood pressure, heart volume and total amount of hemoglobin increased up to and including the 12 month control but thereafter seemed to return to the pre-treatment level. These circulatory changes during the first year of the application of this contraceptive may be as the result of a marked sympathicotonic reaction induced by the steroids. Possibly because of some form of adaptive mechanism, this reaction seems to decrease (and almost to "normalize") during the second year of use.

Adolescent↗
PubMed1979

Clinical experience of naproxen in the treatment of primary dysmenorrhea.

The effect of naproxen, Naprosyn, Syntex, in treatment of primary dysmenorrhea was studied in a double-blind, randomized, placebo controlled multicenter study. Nintyseven women, aged between 18--40 years, with severe dysmenorrhea, were treated with either naproxen, 48 women, or placebo, 49 women, for two consecutive menstrual cycles. No oral contraceptive was used. The patients were allowed to take supplementary analgesics 4--6 hours after the study drug was taken if adequate relief was not achieved. The recommended dose of naproxen was 1--2 tablets, 250 mg, as needed, with a maximum of 5 tablets daily. Medication was started at first sign of menstrual distress. Improvement was achieved in 70 per cent of the women in the naproxen group (good to excellent relief) but only in 30 per cent in the placebo group. This difference is statistically significant (p less than 0.001). There was much more supplementary medication used in the placebo group compared to the naproxen treated patients (p less than 0.001). Fewer patients had to stay in bed, or stay at home from work or school, in the naproxen group compared to the placebo group. Few side-effects were reported and most of them belonged to the dysmenorrhea symptomatology. No side-effects could be rement according to the patients' own judgement.

Adult↗
PubMed1978

Antihypertensive treatment with the adrenergic beta-receptor blocker metoprolol during pregnancy.

In 101 hypertensive gravidae the selective beta-blocking agent metoprolol alone or in combination with hydralazine has been used. The effects of the mother and fetus have been compared with those of 97 hypertensive gravidae treated with hydralazine. In both groups a small dose of a thiazide was added. Perinatal mortality was lower in the metoprolol group (2.0%) than in the hydralazine group (8.0%). The rate of fetal growth retardations also was lower when using metoprolol (11.7 and 16.3% respectively). No abnormal effects of the beta-blocker was noticed on the fetus.

Apgar Score↗
PubMed1978

Vacuum aspiration at therapeutic abortion: blood loss at operation in multigravid women.

Therapeutic abortion by vacuum aspiration in the first trimester was carried out on 129 healthy multigravid women. The loss of haemoglobin at operation was estimated and the volume of blood calculated. The figures were compared to those in a group of primigravid women earlier reported. Blood loss increases with gestational length. Blood loss at first trimester abortion is smaller in multigravid than in primigravid women. In multigravid women blood loss is not significantly influenced by the woman's age and the number of pregnancies.

Abortion, Therapeutic↗
PubMed1978

Vacuum aspiration at therapeutic abortion: influence of two different negative pressures on blood loss during and after operation.

In 167 women blood loss was measured during and after vacuum aspiration for therapeutic abortion in the first trimester of pregnancy. Two different negative pressures were used -49.1 kPa (-0.5 kp/cm2) and -78.5 kPa (-0.8 kp/cm2) in a randomized series. It was found that for the whole first trimester (8--13 weeks) blood loss during and after operation was relatively small and not influenced by the pressure used. In no case blood loss exceeded 500 ml at operation or 60 ml during the first post-operative week. In 6 women post-operative infections were diagnosed.

Abortion, Therapeutic↗
PubMed1977

Pregnancy in the young teenage woman.

Since 1967 the number of delivered young teenage women has gradually decreased. During the same period the number of therapeutic abortions among these young women has increased, probably to a sufficient extent to explain the decreased nativity. There is no evidence in this study of any effect of more extended sex and contraceptive education in schools.

Abortion, Therapeutic↗
PubMed1977

The effect of oxytocin on hypertonic saline abortion.

Oxytocin was infused in 22 randomly selected pregnant women after extraamniotic hypertonic saline instillation. In another 24 pregnant women no oxytocin was infused at midtrimester abortion. There was no difference between the two groups in mean time from saline injection to expulsion of the fetus.

Abortion, Induced↗