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Biomedical subjects

B Strauss

Publications and source records attributed to B Strauss.

At least 19 recordsLinked to original sources

Doping, drugs and drug abuse among adolescents in the State of Thuringia (Germany): prevalence, knowledge and attitudes.

Goal-directed measures to prevent doping and drug abuse in sports requires empirical data. In this connection, a cross-sectional analysis was carried out in 2004. The purpose of the study, on the one hand, was to register reliable data of the current situation in Thuringia, and, on the other hand it was to give information on possible interventional steps with scientific support. Within three months, 2319 adolescents from 16 Thuringian schools (5 regular schools, 4 secondary schools, 3 sport schools and 4 vocational schools) were surveyed. Three hundred and forty-six (15.1 %) students out of 2287 students (26 students without a statement) indicated use of prohibited substances from the WADA list in the previous year: 16 (0.7 %) anabolic-androgenic steroids (AAS), 10 (0.4 %) growth hormones, 56 (2.4 %) stimulants, 305 (13.2 %) cannabis, 2 (0.1 %) diuretics, 52 (2.2 %) cocaine/heroin and 6 (0.3 %) erythropoeitin. Moreover, nonathletes (N = 490) reported a substance use that was approximately 5.0 % higher than that of recreational athletes (N = 1254) and nearly three times higher than that of competitive athletes (497). All three groups (nonathletes, recreational athletes and competitive athletes) performed poorly on a knowledge test regarding doping in general with an average below 60 % in each case. Another main aspect of the study was to determine factors influencing substance use in sports. Besides the doping specific knowledge (beta = 0.06, p < 0.05), age contributed (beta = 0.09, p < 0.05), as well as anti-doping attitude (beta = -0.34, p < 0.05), to the resulting variance. Gender, however, played no role. The findings of the study point towards the need for improvement of specific knowledge of doping among students and that their attitude towards doping must be altered. The goal in this case is to test the effectiveness of appropriate scientific intervention.

Adolescent↗

[Selection of medical students by medical faculties. Problems and advantages for universities].

Due to the amendment of the framework act for higher education in summer 2004, the German universities have to select 60% of the students within all disciplines with limited access (including medicine) by themselves. This requirement fits with the political intention to enhance the achievement of a specific profile and competition among the universities. The first implementation of the legal requirement has shown that the universities were insufficiently prepared to apply selection criteria amending high school grades. Theoretically, a variety of criteria could be considered whose suitability has to be evaluated carefully. Existing evidence related to these criteria is summarized in this article. The implementation of new tools for student selection will raise a variety of problems related to the quality of organisation, but also other aspects of quality assurance. It can be assumed that, in the long run, centrally developed tests will be applied within medicine that might be completed with other selection tools locally.

Curriculum↗

Differential efficacy of group and individual/couple psychotherapy with infertile patients.

BACKGROUND: The diagnosis of infertility and concurrent medical treatment may inflict an array of negative emotional symptoms in infertile persons. Evidence for the positive effects of psychotherapy on negative affect and also possible influence on conception rates has been discussed in several studies. METHOD: Meta-analyses were conducted in order to evaluate the efficacy of group and individual/couple therapies on (i) the reduction of negative emotional symptoms, and (ii) the possible promotion of pregnancy. RESULTS: Group and individual/couple psychotherapy led to a decrease in feelings of anxiety. Upon termination of psychotherapy, a reduction of depressive symptoms in patients was greater after 6 months. Psychotherapy accompanying IVF treatment yielded similar conception success rates to psychological interventions administered to patients not in specific medical care. CONCLUSION: Results are suggestive of positive effects of psychotherapy for infertile patients. However, these results must be viewed with caution due to methodological and informational bias within the studies analysed.

Anxiety↗

[Psychoreactive disorders after motor vehicle accidents. Is it possible to predict the development of psychoreactive disorders after motor vehicle accidents?].

The aim of this study was to assess common risk factors for the early development of psychoreactive disorders during traumatological treatment and to estimate their predictive potential. The sample consisted of 126 consecutive patients with accidental injuries recruited in an emergency room of the university hospital. We assessed this population 1 week (T1) and-on average-8 months following the accident (T2). At T1 34.5% of all patients indicated moderate and 26.4% strong symptoms of an acute stress disorder; 26.7% of all patients assessed at T2 suffered from severe post-traumatic symptoms. Linear regression analysis, using morbidity status at T2 as the dependent variable, allowed the explanation of 46.2% of the variance. The degree of early acute stress symptoms, injury, and pain intensity contributed significantly to the predictive model. We conclude that a substantial proportion of severely injured accident victims that will develop PTSD can be screened to some degree by the assessment of early stress disorder, the degree of their injury, and pain intensity, enabling secondary prevention of trauma-dependent symptomatology.

Accidents, Traffic↗

[The effect of brimonidine on the pupillary reflex. A pupillographic study in healthy volunteers].

PURPOSE: The effect of brimonidine in comparison with acetazolamide on pupillary reflex was investigated in 18 volunteers. METHODS: Infrared pupillography was performed with white diode light of 200 ms duration to measure pupil diameter, constriction latency, reaction time, constriction amplitude, and relative constriction amplitude. The measurements were performed according to a fixed schedule including a phase without medication to determine the baseline level. Data were analyzed by Student's paired t-test. RESULTS: Application of brimonidine and acetazolamide led to a significantly reduced intraocular pressure as well as static and dynamic differences in the pupillary reflex. The pupil diameter measurements were significantly smaller after both medications in comparison to baseline. The reduction of pupil diameter after brimonidine led to significantly reduced contraction amplitude and prolonged latency. CONCLUSION: Application of brimonidine leads to significant miosis, which might due to the affinity to alpha(2)-receptors with reduction of noradrenaline release in the synapse. This effect may play a role in a higher decrease of intraocular pressure by increasing aqueous humor outflow in comparison to clonidine and apraclonidine, but further investigations are required.

Acetazolamide↗

A prospective study of rural drinking water quality and acute gastrointestinal illness.

BACKGROUND: This study examined the relationship between the bacteriological contamination of drinking water from private wells and acute gastrointestinal illness (AGII), using current government standards for safe drinking water. METHODS: A prospective cohort study was conducted using 235 households (647 individuals) randomly selected from four rural hamlets. Data were collected by means of a self-administered questionnaire, a self-report diary of symptoms and two drinking water samples. RESULTS: Twenty percent of households sampled, had indicator bacteria (total coliform or Escherichia coli (E. coli)) above the current Canadian and United States standards for safe drinking water. No statistically significant associations between indicator bacteria and AGII were observed. The odds ratio (OR) for individuals exposed to E. coli above the current standards was 1.52 (95% confidence interval (CI), 0.33-6.92), compared to individuals with levels below current standards. The odds ratio estimate for individuals exposed to total coliforms above the current standards was 0.39 (95% CI, 0.10-1.50). CONCLUSIONS: This study observed a high prevalence of bacteriological contamination of private wells in the rural hamlets studied. Individual exposure to contaminated water defined by current standards may be associated with an increased risk of AGII.

Acute Disease↗

[Hairdex: a tool for evaluation of disease-specific quality of life in patients with hair diseases].

Because of a strong reduction of life quality in patients with hair loss, a special questionnaire was developed following the general Skindex questionnaire for dermatoses. The Hairdex was evaluated in 75 female hair patients. The aim of the study was to prove the questionnaire's statistical values, reliability, validity, general acceptance and accuracy. The clinical manifestation of hair loss was categorized as "not visible", slightly visible" and "obviously visible". The hair loss lead to great differences in the life quality of both the patients with obvious hair loss and in patients with non-visible hair loss, especially in the categories "emotions", "self-confidence" and "stigmatization". The convergent and discriminant validity of the questionnaire was satisfactory. The acceptance of the questionnaire was very good with 90%. The hairdex-questionnaire represents a reliable and patient-oriented instrument for evaluation of life quality in hair diseases. The reliability of the questionnaire concerning longitudinal therapeutic effects will need to be investigated in further studies.

Adult↗

[not app].

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Editorial↗

[Farewell to the dodo-bird: specific versus general psychotherapy from the perspective of psychotherapy research].

Based upon different specificity problems in psychotherapy, it is shown that psychotherapy research consists of two different worlds, the one focussing on disorder specific factors, the other traditionally investigating unspecific or common therapeutic factors. Relating to the Dodobird verdict that has been used to describe the so-called equivalence paradox in psychotherapy, several views of common therapeutic factors are summarized. Recent research shows that psychotherapy research also indicates a specificity paradox that can be resolved by the observation that several psychological disorders develop their own dynamics and that--besides this--general principles are active. In several settings and in relation to specific disorders both aspects have already been integrated successfully.

Humans↗

Guidelines for counselling in infertility: outline version.

The Guidelines for Counselling in Infertility describe the purpose, objectives, typical issues and communication skills involved in providing psychosocial care to individuals using fertility services. The Guidelines are presented in six sections. The first section describes how infertility consultations differ from other medical consultations in obstetrics and gynaecology, whereas the second section addresses fundamental issues in counselling, such as what is counselling in infertility, who should counsel and who is likely to need counselling. Section 3 focuses on how to integrate patient-centred care and counselling into routine medical treatment and section 4 highlights some of the special situations which can provoke the need for counselling (e.g. facing the end of treatment, sexual problems). Section 5 deals exclusively with third party reproduction and the psychosocial implications of gamete donation, surrogacy and adoption for heterosexual and gay couples and single women without partners. The final section of the Guidelines is concerned with psychosocial services that can be used to supplement counselling services in fertility clinics: written psychosocial information, telephone counselling, self-help groups and professionally facilitated group work. This paper summarizes the different sections of the Guidelines and describes how to obtain the complete text of the Guidelines for Counselling in Infertility.

Counseling↗

Vulvar pain. Psychological profiles and treatment responses.

OBJECTIVE: To compare the psychological and quality of life profiles of women with different subsets of vulvodynia and identify differential response patterns to a combined gynecologic-dermatologic treatment program. STUDY DESIGN: Fifty-three women with vulvar dermatoses, dysesthetic vulvodynia and vulvar vestibulitis were recruited from a combined dermatologic and gynecologic vulvar clinic and completed instruments related to quality of life (QoL) and psychologic symptomatology. A repeated measurement design was employed. However, only 33 women could be assessed at the second point of measurement. RESULTS: Women with different subsets of vulvodynia showed (1) distinct quality of life and psychological profiles, and (2) different response patterns to treatment. There were significant differences on most QoL scales, with patients with dysesthetic vulvodynia and with vulvar dermatoses showing greater impairment than patients with vestibulitis. However, patients with vestibulitis displayed a highly specific pattern of psychologic symptomatology. Patients with vulvar dermatoses had an improvement in problems related to intimacy than patients with vulvar pain syndromes. CONCLUSION: Treatment intervention studies seem to be indispensable in order to gain a better understanding of the complex interplay between different subsets of vulvodynia and psychological symptoms concurrently with differential treatment reactions.

Adult↗

Computer-based three-dimensional visualization of developmental gene expression.

A broad understanding of the relationship between gene activation, pattern formation and morphogenesis will require adequate tools for three-dimensional and, perhaps four-dimensional, representation and analysis of molecular developmental processes. We present a novel, computer-based method for the 3D visualization of embryonic gene expression and morphological structures from serial sections. The information from these automatically aligned 3D reconstructions exceeds that from single-section and whole-mount visualizations of in situ hybridizations. In addition, these 3D models of gene-expression patterns can become a central component of a future developmental database designed for the collection and presentation of digitized, morphological and gene-expression data. This work is accompanied by a web site (http://www.univie.ac.at/GeneEMAC).

Anatomy, Cross-Sectional↗