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Biomedical subjects

C A Gooding

Publications and source records attributed to C A Gooding.

At least 73 records · Page 4Linked to original sources

Medially deployed thoracostomy tubes: cause of aortic obstruction in newborns.

It was observed that severe aortic displacement, narrowing, and obstruction can occur when thoracostomy tubes abut the mediastinum. To further investigate this previously undescribed phenomenon, aortography was performed with intraluminal pressure measurements in newborn puppies and aortograms obtained in two infant cadavers. In the puppies, when the tube tip pressed against the descending thoracic aorta, aortic pressure below that site decreased and aortic arch pressure rose. When the tube tip pressed against the ascending aorta, pressures in the aortic arch and abdominal aorta decreased. Aortography in the puppies and infant cadavers demonstrated aortic displacement, narrowing, and obstruction when the thoracostomy tubes abutted the mediastinum. The clinical consequences of malpositioned thoracostomy tubes were observed in two premature infants. When the posteromedially deployed tubes were partially withdrawn, systolic arterial pressures, which had been exceptionally low, suddenly and significantly increased distal to the tube tip. Medially deployed thoracostomy tubes may represent a potential hazard to the newborn infant.

Animals↗

Abdominal disease in children: a comparison of computed tomography and ultrasound.

Diagnoses from computed tomographic (CT) and ultrasonic examinations of the abdomen in 29 pediatric patients were reviewed retrospectively to compare the sensitivity and specificity of the two methods for detection of abnormalities and to assess their differential diagnostic accuracies. No difference in sensitivy (87%) and specificity (100%) was observed between the two imaging methods. However, the differential diagnostic accuracy in abnormal cases was greater with CT than ultrasound. The combined information from CT and ultrasound allowed for correct diagnoses in all but three instances. Findings from each technique considered separately would have resulted in erroneous diagnoses in four instances using CT and nine instances using ultrasound. Diagnostic information obtained from CT and ultrasound examinations were complementary in many instances.

Abdomen↗

The right paratracheal stripe in children.

The width of the right paratracheal stripe (RPS) has been established in normal adults but not in normal children. The thymus and great vessels are relatively larger in children than in adults and could obscure or widen the RPS. We found that obscuration does occur and, therefore, the RPS is less often measurable in children than in adults. Widening by the thymus and great vessels, however, does not occur. The width of the RPS in normal children, 0.5 to 3.0 mm, is slightly less than in adults. From this study of normal children and our subsequent experience with pediatric patients, we conclude that in a child an RPS 4 mm or wider is reliable evidence of disease affecting the trachea, mediastinum, or pleura.

Adolescent↗

Computed body tomography in children: evaluation of 45 patients.

Computed tomographic (CT) body scans from a series of 45 infants and children were reviewed for the indications leading to the examinations, for technical quality of the images, and for diagnostic value of CT scanning. Useful diagnostic information was obtained in 30 of the 39 cases with technically satisfactory images. Individual case reports of CT examinations including findings from other imaging studies demonstrate how CT can interface with other methods to yield additional diagnostic information. Methods of patient preparation and suggested indications for CT body scan examinations of children are presented.

Adolescent↗

Computed tomographic scanning in children: comparison of radiation dose and resolving power of commercial CT scanners.

Surface and internal radiation doses for abdominal computed tomography (CT) of children were determined using child-sized phantoms and seven models of CT body scanners. Resolving power of each scanner was determined simultaneously with the radiation dose determination. The average surface skin dose for a complete CT body examination ranged from 0.39 to 5.60 rad, varying with patient size and model of CT scanner employed. A high contrast (12%) resolving power phantom of water-filled holes in acrylic showed a range of 1.75--2.25 mm.

Child↗

Asymmetric lung involvement in bronchopulmonary dysplasia.

The radiographic distribution of pulmonary abnormalities in bronchopulmonary dysplasia (BPD) in all previously reported cases has been bilateral and generalized. The authors studied 11 premature infants who had BPD that was primarily unilateral. The striking feature in each of these patients was the occurrence of an episode of prolonged unilateral atelectasis or tension pneumathorax. Few, if any, radiographic manifestations of BPD developed. Results of a detailed analysis of oxygen exposure and respirator therapy during the periods of unequal lung ventilation further characterizes the protective effect of atelectasis and tension pneumothorax in the development of BPD.

Female↗

Radiographic features of colitis associated with the hemolytic-uremic syndrome.

Four cases of colitis associated with the prodromal phase of the hemolytic-uremic syndrome are presented. Abnormalities demonstrable on barium enema examination consist of prominent filling defects, marginal serrations, and mucosal edema. Segmental bowel dilatation and areas of stenosis may also be present. Although nonspecific in itself, this appearance of the colon when correlated with the clinical history and peripheral blood smear should enable the radiologist to suggest the diagnosis of hemolytic-uremic syndrome.

Child↗

Angiographic and ultrasonographic appearance of renal cortical and medullary necrosis in the newborn.

Renal cortical and medullary infarction are 2 of the severe complications of perinatal asphyxia and shock. The angiographic and ultrasonographic findings in these conditions have not been described previously. They demonstrate nephromegaly, a nonhomogeneous nephrogram, and internal echoes. Similar findings may be seen in renal vein thrombosis, hydronephrosis, and polycystic kidneys.

Angiography↗

Pneumonitis following inclusion blennorrhea.

A pregnant woman and her husband had proved chlamydial genital tract infections. She gave birth to a male infant who developed inclusion blennorrhea (inclusion conjunctivitis of the newborn infant). While on topical chemotherapy for his eye disease, the infant developed pneumonitis. Chlamydiae were recovered from his sputum at a time when conjunctival specimens were sterile. This finding raises the possibility that the agent of inclusion conjunctivitis may cause systemic infections in neonates exposed during passage through an infected birth canal.

Chlamydia↗

Compression of superior sagittal sinus by neonatal calvarial molding.

Compression of the superior sagittal sinus may result from overlapping of the parietal and occipital bones in the newborn infant. Such compression has been documented angiographically and the resultant decreased blood flow confirmed with a Doppler ultrasound probe. This compression may increase intracerebral venous pressures and thereby contribute to the high incidence of intracerebral hemorrhage in premature infants with respiratory distress syndrome.

Cerebral Angiography↗

Compensatory renal hypertrophy after treatment for Wilms' tumor.

In children who undergo nephrectomy for Wilms' tumor, compensatory renal hypertrophy occurs rapidly despite concomitant irradiation and chemotherapy. Review of preoperative and postoperative intravenous pyelograms of 21 children showed all to have significant enlargement of the remaining kidney. Sixty-five per cent renal hypertrophy occurred during the first 2 months after nephrectomy; by 11 months, renal hypertrophy is complete and renal growth is no longer accelerated.

Child, Preschool↗