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Biomedical subjects

C Anand

Publications and source records attributed to C Anand.

26 records · Page 2Linked to original sources
PubMed1991

Prevention of cubitus varus deformity in supracondylar fractures of the humerus.

Based on cadaveric experiments, peroperative observations and clinical study, an exact mechanism is described by which full pronation of the forearm prevents cubitus varus deformity in supracondylar fractures of the humerus. The significance of the position of the upper limb in relation to the chest is described, and it has been demonstrated that even the posterolaterally displaced supracondylar fractures are better reduced and maintained in pronation.

Adolescent↗
PubMed1991

Occurrence of lymphocytotoxins in multi-case rheumatoid arthritis families: relation to HLA.

The presence of lymphocytotoxic antibodies (LCA) and their association with HLA haplotypes has been studied in 27 multi-case rheumatoid arthritis (RA) families (13 multiplex and 14 simplex) in Northern India. Of the total 59 RA patients, 69.4% had cytotoxins in their sera as compared with 2.5% of healthy controls. No differences were observed in the frequency of LCA in relation to sex and rheumatoid factor. LCA against B cells were significantly more predominant than those against T cells. Twenty families studied for correlation of HLA with LCA showed greater intensity of reaction with DR4+ haplotypes, particularly in simplex families. Similarly, the frequency of LCA among patients and unaffected parents was greater in simplex compared with multiplex families. Haplotype sharing with the patient was increased in the relatives positive for cytotoxins in these families. An immunogenetic contribution made by the affected parent and a common environmental stimulus may be responsible for the increased production of LCA in multi-case families with RA.

Antilymphocyte Serum↗
PubMed1988

Duplication of optic canals in human skulls.

Three human skulls showing duplication of the optic canal are reported. Two had bilateral duplication while one had duplication on one side only. The measurements of the whole canal were within the range of normal. Septa of variable thickness separated the main and the accessory canals in these skulls and the skulls also showed a tendency to excessive bone formation.

Cephalometry↗
PubMed1975

Interactions of carbenicillin and ticarcillin with gentamicin.

The in vitro inactivation of gentamicin by carbenicillin and a new semisynthetic penicillin, ticarcillin (BRL 2288), has been demonstrated. Gentamicin half-lives have been studied in eight patients with end-stage renal failure, and a 25 to 74% reduction in half-life has resulted from the concomitant administration of therapeutic doses of carbenicillin and ticarcillin.

Carbenicillin↗
PubMed1975

Effects of 5-fluorouracil on exocrine glands. III. Fine structure of Brunner's glands of rats.

Effects of a pyrimidine analogue, 5-fluorouracil (Fur), have been studied by electron microscopy and by electron microscopic cytochemical techniques. Previous studies have demonstrated that rats show serious gastrointestinal disturbances 5 days after 3 daily injections of FUR (50 mg/kg). The present investigation demonstrates that Brunner's glands under the same conditions suffer certain cytological changes involving the Golgi apparatus, where a notable reduction in the number of Golgi stacks is observed. The vacuolar components in the Golgi complex appear empty. Cytochemical localizations of uridine diphosphatase and thiamine pyrophosphatase activities, however, are normal. The reaction products are localized in the distal two or three lamellae of the Golgi stack and within the secretory granules nearby. In addition reaction products are present along the apical plasma membrane on the luminal side, suggesting a possible movement of these membranes from the Golgi stack, via secretory granules, to the apical plasma membrane.

Acid Phosphatase↗
PubMedDate not supplied

Do the beta-hemolytic non-group A streptococci cause pharyngitis?

Implication of the beta-hemolytic non-group A streptococci (BHNAS) as pharyngeal pathogens has been based predominantly on reports of a few outbreaks, small case clusters, and anecdotes. These organisms have long been noted to constitute a significant number of the beta-hemolytic streptococcal isolates from throats of symptomatic and asymptomatic patients in a variety of populations. Laboratory studies have demonstrated the usefulness of anaerobic atmosphere and prolonged incubation in maximizing isolation of the BHNAS. More recently, genetic studies have furthered our appreciation of the taxonomy and have defined two major groups: Streptococcus anginosus-milleri group and large-colony BHNAS; the latter can be further separated on the basis of serogrouping and biotyping. Recognition of this diversity gives justification to the reexamination of the epidemiology and disease course of BHNAS pharyngitis. Treatment studies will also be required if all or subsets of these organisms can be confirmed as pharyngeal pathogens.

Carrier State↗