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C B Collier

Publications and source records attributed to C B Collier.

30 records · Page 2Linked to original sources
PubMed1981

Epidural morphine.

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Anesthesia, Epidural↗
PubMed1980

Suxamethonium fasciculations: a topographical study.

It has been found in a group of 455 gynaecological patients that not all the voluntary muscles of the body respond to suxamethonium in the same way. One group of muscles (e.g. biceps) which is sensitive to suxamethonium, responds by fasciculating in almost every individual. A second, resistant, group of muscles (e.g. pectoralis major) is almost totally unresponsive to suxamethonium. A third muscle group (e.g. triceps) shows fasciculations in about 60% of cases and appears intimately associated with the development of suxamethonium pains, for if fasciculations do occur then suxamethonium pains are likely to ensure, but not necessarily involving all the fasciculating muscles. A theory to account for these different groups has been proposed involving the known variation in distribution of red and white muscle fibres throughout the body.

Adolescent↗
PubMed1979

Dantrolene and suxamethonium. The effect of pre-operative dantrolene on the action of suxamethonium.

A single oral dose of dantrolene (100--150 mg) given at least 2 hr pre-operatively has been found to reduce significantly the strength of muscular fasciculations, the hyperkalaemia and the incidence of muscle pains following suxamethonium (from 56 to 4%) in a series of forty-eight patients compared with controls. The biceps EMG of the fasciculations was unchanged by dantrolene; the incidence of troublesome side effects was low (9%) and there did not appear to be any alteration in the duration of action of suxamethonium.

Adult↗
PubMed1978

Suxamethonium pains and early electrolyte changes.

Significant changes in the plasma electrolytes were found in a group of ninety-two female patients in the first 5 min following suxamethonium administration. The plasma potassium rose to a higher level in those patients who developed suxamethonium pains than in those who did not; the plasma calcium decreased in the former group, but increased in the latter. The plasma sodium decreased early in most patients, with the greatest reduction in those patients who did not develop symptoms. A decrease in the level of plasma calcium at 1 min correlated well with the incidence of 'the pains'. There were significant differences in the electrolyte changes, depending on whether thiopentone or Althesin was used for induction, but there was no difference in the incidence of suxamethonium pains. Suxamethonium pains are attributed to damaged muscle-spindles with enhanced calcium release playing an important part.

Adolescent↗
PubMedDate not supplied

Epidural catheters for obstetrics. Terminal hole or lateral eyes?

BACKGROUND AND OBJECTIVES: Controversy exists over the choice of the ideal epidural catheter for obstetric use, particularly whether the catheter should have a single terminal hole or three lateral eyes. METHODS: A randomized single-blind study of 200 obstetric patients undergoing epidural block for analgesia in labor or for cesarean delivery was undertaken, using either a catheter with a terminal hole or three lateral eyes. The extent and quality of the block was recorded, as well as the presence of any complications. RESULTS: The study was abandoned after 102 patients had been assessed, as the incidence of unsatisfactory blocks with terminal eye catheters was found to be unacceptably high (32%), when compared with the lateral eye catheters (12%) (P < .05). Four of the terminal eye catheters (8%) had to be resited compared with one of the lateral eye catheters (2%). One case of intravascular injection (2%) occurred through a terminal eye catheter, despite repeated negative attempts at aspiration. CONCLUSIONS: The use of terminal eye epidural catheters in our obstetric patients has led to an unacceptably high incidence of both unsatisfactory blocks and catheter replacement. Lateral eye catheters produced better results in our circumstances.

Analgesia, Epidural↗