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Biomedical subjects

C Bengtsson

Publications and source records attributed to C Bengtsson.

At least 217 records · Page 12Linked to original sources
PubMed1981

Bone mineral content in relation to age and menopause in middle-aged women. A study of bone density in lumbar vertebrae by dual photon absorptiometry in a population sample of women.

As one phase of a comprehensive population study of women, bone density was determined in the third lumbar vertebra by dual photon absorptiometric technique. The method involves the use of two radionuclides, which both emit gamma radiation but with different energies (241Am with 59.6 keV and 137Cs with 662 keV). Women in three age strata were studied: 46, 54 and 62 years. The bone mineral content was higher in premenopausal or recently postmenopausal 54-year-old women than in women of the same age who had been postmenopausal for a long time (p less than 0.02). A similar trend was found for women aged 62. The differences could not be explained by differences in other factors studied, such as body height, body weight, smoking habits, numbers of pregnancies or physical inactivity. No significant differences were found when women with similar menstrual status in different age-groups were compared. In the ages studied, hormonal factors seem to be more important than the age per se for the development of oeteoporosis.

Aging↗
PubMed1981

Seven years on a selective beta-blocker - metoprolol. A long-term study of women with arterial hypertension.

Women with previously untreated arterial hypertension have been followed up during ten years of beta-blocker treatment, first for three years with alprenolol and then for seven years with the selective beta1-blocker metoprolol. During a long-term follow-up, blood pressure levels remained at acceptable levels in all the 24 women studied during the period with alprenolol as well as during the period with metoprolol. Both drugs were well tolerated. In no case had the beta-blocker to be stopped because of side-effects. No changes ascribed to beta-blocker treatment were found when a number of laboratory data were repeatedly studied. Administering the drug b.i.d. seemed preferable to a t.i.d. administration. The majority of the subjects had their blood pressure well-controlled when the drug was administered once a day, and a once-daily regimen could probably be used in most patients with uncomplicated arterial hypertension. However, a few patients have their blood pressures better controlled with a b.i.d. regimen and some patients experienced side-effects when taking the drug once a day; these disappeared when the drug was taken b.i.d. It is therefore concluded that the choice between b.i.d. administration and a one-dose administration should be made individually for each patient.

Adrenergic beta-Antagonists↗
PubMed1980

Sleep disturbances, nightmares and other possible central nervous disturbances in a population sample of women, with special reference to those on antihypertensive drugs.

Of 1302 women aged 44-66 years in a population study in Göteborg, Sweden, in 1974-75, who were representative of women of all the ages studied in the area, 165 were taking antihypertensive drugs, mostly beta-blockers and diuretics. The prevalence of sleep disturbances, nightmares, tiredness and melancholia or depression was studied in the total population sample, and a comparison was made between women who were or were not taking antihypertensive drugs. In the entire population sample no significant difference was found between the various age strata studied, although with increasing age there was a trend towards fewer complaints of nightmares, but a larger number of sleep disturbances as a whole. No difference was found between women taking or not taking various types of single-drug therapy or combinations of antihypertensive drugs.

Adrenergic beta-Antagonists↗
PubMed1980

Longitudinal studies of anthropometric data and body composition. The population study of women in Götenberg, Sweden.

Anthropometric data and body composition, estimated from total body potassium and total body water determinations, were studied in 1968 to 1968 and 1974 to 1975 in a population sample of middle-aged women. Altogether 1302 women participated in the anthropometric studies and 79 women in the body composition studies on both occasions. Body height decreased with age both secularly and biologically. The reduction of body height was greater at higher ages. Body weight increased with age, the change being partly a cohort effect and partly an effect of age. Evidence of a reduced muscle mass in the arms with age was found. Body cell mass increased with age in some age strata. There was an increase in subcutaneous fat with age, both in the arms and in the trunk. Body fat did not change significantly with age in the age strata studied. A change in body weight was accompanied by a smiliar change in both body fat and body cell mass.

Adult↗
PubMed1980

Obesity in relation to morbidity and mortality from cardiovascular disease.

Representative population samples of middle-aged women (1462 participants, a participation rate of 90.1%) were followed from 1968-1969 for 10 years with respect to morbidity and mortality from myocardial infarction, stroke and all causes of death. The same sample (1302 participants, 80.3%) was studied in 1974-1975. Data on the incidences of angina pectoris, intermittent claudication and hypertension in these women during the 6-year interval were analyzed. Obesity as a premorbid characteristic was estimated by weight index and sum of triceps and subscapsular skinfold thicknesses. The overall trends between weight index and the incidences of myocardial infarction and angina pectoris were weak, while there were excess frequencies in the top quintiles, indicating that only marked obesity constitutes an increased risk. The incidence of hypertension was positively correlated to both indices of obesity. The death rate irrespective of cause was negatively correlated to the sum of skinfolds but was not correlated to the weight index. The death rate from myocardial infarction seemed to be correlated to both obesity indices.

Adult↗
PubMed1980

Obesity in relation to socioeconomic status. A population study of women in Göteborg, Sweden.

In a population sample of 1462 middle-aged women socioeconomic data were studied in relation to obesity, assessed by a body weight index. Education, annual income, and social class were negatively correlated with weight index (WI). Husband's social class was a stronger determinant of obesity in the woman than her own class. Age of husband and number of children were significantly correlated with WI. There was also a weak correlation between being single and WI. Sick leave was not correlated to WI. Pension was correlated to WI when adjusted for age, but not when allowance was also made for social class. Age, husband's social class, education, husband's income, and number of children were independent predictors of WI among the married women. In the single women, age and own income were independent predictors of WI but not number of children, education or own social class.

Adult↗
PubMed1980

Serum lipids, arterial blood pressure and body weight in relation to the menopause: results from a population study of women in Göteborg, Sweden.

Statistically significant differences were found between premenopausal and postmenopausal 50-year-old women for serum cholesterol, serum triglycerides, systolic blood pressure and body weight. Serum cholesterol and serum triglycerides were higher in postmenopausal women, while systolic blood pressure and body weight were higher in premenopausal women. When similar comparisons were performed between premenopausal and postmenopausal women in the other age strata studied, the differences were usually not statistically significant. In women of the same age, serum cholesterol was found to increase and systolic blood pressure to decrease with increasing postmenopausal time. Similarly, in women of the same age serum cholesterol and serum triglyceride levels were found to be lower in women who were to go on menstruating for another couple of years compared to women who were to have their menopause within the next few years.

Adult↗
PubMed1980

Renal stone disease--experience from a population study of women in Gothenburg, Sweden.

An interview concerning previous history of renal stone disease was included when a population study of 1 462 women aged 38--60 years was carried out in 1968-69. About 5% reported a history of renal stone disease. When the women were re-examined six years later, an annual incidence of 3.7 per 1 000 was found. Women with history of new attacks of renal stone disease usually had the same serum calcium and serum uric acid values as other women except for a few with markedly increased serum uric acid values.

Adult↗
PubMed1980

Adipose tissue cellularity in adulthood and its relation to childhood obesity.

A population sample totalling 1462 middle-aged women was studied in 1968-69. A re-study of the same women in 1974-75 comprised 1302 women. Body composition and adipose tissue cellularity were determined in a systematic subsample of 227 women and in a subsample of 76 obese women. There was a significant relation between body build in childhood (evaluated retrospectively as lean, normal or obese) and prevalence and degree of obesity in adulthood. There was a highly significant relation between the body weights in 1968-69 and 1974-75, while a low order negative correlation was found between body weight in 1968-69 and change in weight between 1968-69 and 1974-75. There was a significant relation between fat cell weight and weight index in the lower range and between fat cell number and weight index throughout the whole range studied. Body cell mass correlated with weight index and total fat cell number but not with fat cell weight. There was no significant correlation between body cell mass and obesity in childhood. There was a significant relation between degree of obesity and total fat cell number when age of onset was kept constant, but not between age of onset and total fat cell number when degree of obesity was kept constant. An association between childhood obesity and obesity in adulthood was shown. However, the concept of a critical period in childhood for changes in total fat cell number was not supported.

Adipose Tissue↗
PubMed1980

Bacteriuria in a population sample of women. Prevalence, characteristics, results of treatment, and prognosis.

The prevalence of bacteriuria was studied in a population sample of women aged 38-60. Significant (greater than or equal to 100 000 bacteria/ml of the same species in two consecutive specimens) or "probable" bacteriuria (greater than or equal to 100 000 in the first and 20 000-90 000 bacteria/ml of the same organism in the second specimen) were found in 5% of the women, increasing from 3.5% in women aged 38 to 8.6% in women aged 60. Escherichia coli predominated (90% of those with significant bacteriuria), and 91% of the Escherichia coli strains were sensitive to sulphonamides. About half of the women who were non-bacteriuric after short-term treatment had one or more recurrent urinary tract infections during a two-year follow-up period. Serum creatinine and urine concentrating capacity did not differentiate women with significant or "probable" bacteriuria from the others. Pathological radiological changes were found in 17% of bacteriuric women who were submitted to i.v. pyelography. When re-examined six years after the first study, 23% of initially bacteriuric and 5% of initially non-bacteriuric women had bacteriuria. Patients with renal lesions have been followed for ten years, but none of them has developed progressive renal impairment. Three women with chronic pyelonephritis and acute pyelonephritic attacks in the past were discovered when screening the concentrating capacity in this population sample, but they were non-bacteriuric when screening for bacteriuria. A study of this kind must be conducted over many years before valid conclusions can be drawn.

Adult↗
PubMed1979

Is the menopausal age rapidly changing?

A population study of women in Goteborg, Sweden was carried out in 1968--1969. Altogether 1462 women participated (participation rate 90.1%). Five age strata were studied: 38, 46, 50, 54 and 60 (women born in 1930, 1922, 1918, 1914 and 1908, respectively). The same women were re-studied in 1974--1975. Information about menopausal state and, in postmenopausal women, about menopausal age was obtained on both occasions. The information given by the women in 1974--1975 agreed well with the information given in 1968--1969. Very few women started to menstruate again, if the interval since the last menstruation had been 6 mth or longer. The vast majority of the women had a spontaneous menopause. The medians of menopausal age were found to be between 49 yr 7 mth (in women born in 1908) and 50 yr 5 mth (in women born in 1918). There was a tendency towards a continuously increased menopausal age with time as judged from women born in 1908, 1914 and 1918, respectively, but women born in 1922 were found to have a median menopausal age which was more similar to that of the women born in 1908 than that of the women born in 1918. Our sstudy has, thus, not supported the view that the menopausal age in rapidly changing.

Aged↗
PubMed1979

Menopausal effects on risk factors for ischaemic heart disease.

Women of almost identical age but with a different menopausal state were compared in a population study of women, which was carried out in Goteborg, Sweden. The group of women aged 50 comprised about the same number of still menstruating and postmenopausal women and was, therefore, especially suitable for such a comparison. Serum cholesterol and serum triglycerides were higher in postmenopausal than in premenopausal 50-yr-old women and seemed to increase with postmenopausal time. The differences between premenopausal and postmenopausal women were hightly significant. Systolic blood pressure was slightly but significantly different (lower in postmenopausal women), while no difference was found for diastolic blood pressure. It seems that differences in risk factors for ischaemic heart disease could explain part of but not all the association between early menopause and ischaemic heart disease.

Adult↗
PubMed1979

The effect of smoking on menopausal age.

A comprehensive population study of women in Goteborg, Sweden was carried out in 1968--1969. Altogether 1462 women in five age strata were studied. The age stratum 50 comprised about the same number of postmenopausal women (n = 161) and women who still menstruated (n = 168). A comparison could, therefore, be made between still menstruating and postmenopausal women of almost identical age. In postmenopausal 50-yr-old women 50% were smokers compared to 26% in 50-yr-old women who still menstruated. The difference was highly significant. Almost all the postmenopausal women had been smokers for many years, which means that they did not start smoking as a consequence of the menopause. It thus seemed that an earlier menopause was a consequence of smoking. The difference could not or only to a small extent be explained by other factors such as differences in body weight between smokers and non-smokers.

Adult↗
PubMed1979

Age at menopause and its relation to osteoporosis.

As one phase of a comprehensive population study of women, bone density was determined in the third lumbar vertebra by dual photon absorptiometric technique. The method involves the use of two radionuclides, which both emit gamma radiation but with different energies (241Am with 59.6 keV and 137Cs with 662 keV). Women in three age strata were studied: 46, 54 and 62 yr. All women aged 46 were still menstruating, while the age strata 54 and 62 were subdivided into two groups: those who still menstruated or had been postmenopausal for a short time and those who had been postmenopausal for many years. The bone mineral content was higher in premenopausal or recently postmenopausal 54-yr-old women than in women of the same age who had been postmenopausal for a long time (P less than 0.01). A similar trend was found for women aged 62 (P less than 0.10). The differences could not be explained by differences in other factors studied, such as body weight, body height, smoking habits or physical activity. No significant differences were found when women with similar menopausal status in different age groups were compared.

Adult↗
PubMed1979

Body composition in middle-aged women with special reference to the correlation between body fat mass and anthropometric data.

A variety of anthropometric measurements was made in a randomized population sample of middle-aged women in five age strata in whom body composition was estimated from total body potassium and total body water determined by whole body counting and isotope dilution technique, respectively. No significant differences with age were found for total body potassium or total body water. A significant age difference was found for body fat mass. Simple linear correlations between anthropometric variables and body fat mass estimates were found to be 0.90, 0.86, 0.77 for body weight, buttock circumference, and sum of triceps and subscapular skinfold thicknesses, respectively. Multiple regression analysis showed that these three variables accounted for 80 to 91% of the variation in body fat in the different age strata studied. Multiple regression equations for prediction of body fat from anthropometric variables are given. In about two-thirds of the subjects, the difference between predicted body fat mass and estimated body fat mass was found to be less than +/- 2.5 kg.

Adipose Tissue↗