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Biomedical subjects

C C Draper

Publications and source records attributed to C C Draper.

At least 55 records · Page 3Linked to original sources

A strain of Plasmodium vivax characterized by prolonged incubation: morphological and biological characteristics.

Numerous strains of P. vivax, distinguishable chiefly by their biological characteristics, are known to exist. Two main varieties are recognized: the so-called temperate and tropical strains. The most extreme example of the former-designated by Nikolaev as P. vivax hibernans-constantly exhibited an extremely long incubation period. The strain is no longer in existence and no type material has been preserved. In its place, a North Korean strain with a generally long incubation period has been studied and compared with the well-known tropical Madagascar strain, which frequently but not constantly has a short incubation period. The data presented here concern the behaviour of various strains from the USSR and the morphological characteristics of the North Korean and Madagascar strains. Splenectomized chimpanzees were used as the host of these parasites, particularly in regard to exoerythrocytic schizogony. Attempts were also made, by late biopsies of the liver of the apes, to elucidate the prolonged latency of the North Korean strain. Although there was no evidence of specifically dormant forms, it is probable that certain sporozoites fail to develop in the normal time and that they are reactivated by an unknown factor a year or more after inoculation.

Animals↗

Malaria in the United Kingdom.

Over the past decade the United Kingdom had the second highest number of cases of imported malaria among European countries. There has been a substantial rise in recorded cases of malaria during the past three years though some of it may be due to improved notification. Fatal cases of malaria in visitors to Africa have averaged 6.5% of reported infections due to Plasmodium falciparum. Attacks of vivax malaria may occur several months after travellers return from a malarious country.

Emigration and Immigration↗

A cytoplasmic polyhedrosis virus in midgut cells of Anopheles stephensi and in the sporogonic stages of Plasmodium berghei yoelii.

Although it has been known for some time that nuclear and cytoplasmic polyhedrosis viruses may infect the larval stages of mosquitos capable of transmitting mammalian malaria this paper reports for the first time the presence of a cytoplasmic polyhedrosis virus in adult Anopheles stephensi. The virus was shown to be present in sporogonic stages of Plasmodium berghei yoelii with which the mosquitos were infected. It is possible that other viruses may affect both vector and malaria parasites. Further studies are required of viral infections in mosquitos as a possible method of biological control.

Animals↗