Benign cephalic histiocytosis.
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Biomedical subjects
Publications and source records attributed to C Commens.
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Bindii dermatitis is a distinctive eruption occurring in some Australian children during spring and early summer and characterized by discrete erythematous papules with puncta, concentrated over the palms, soles, and knees. In three affected individuals (but not in thirteen controls), pricking the skin with bindii seed produced an erythematous, indurated papule that appeared within 48 hours of intradermal pricking and simulated the primary lesion. Pathogenesis may involve an allergic reaction with a retained depot of antigen rather than a nonspecific foreign body injury reaction.
The ultrastructure of the cornoid lamella and adjacent epidermis was studied by transmission electron microscopy in seven patients with disseminated superficial actinic porokeratosis (DSAP). In the region of the cornoid lamella similar ultrastructural changes were seen in various degrees in all cases. The main changes were seen in various degrees in all cases. The main changes included reduplication of the basal lamina at the dermo-epidermal junction, vacuolar change in the keratinocytes with numerous autophagic vacuoles, glycogen accumulation, dyskeratotic cells, parakeratotic cells containing degraded organelles, and a reduced granular layer.
A typical skin lesion from a patient with biopsy-confirmed disseminated superficial actinic porokeratosis (DSAP) was examined by scanning electron microscopy. The lesion was rimmed by a prominent but discontinuous cornoid lamella. The cornoid lamella was found to consist of a packed layer of keratinocytes whose orientation varied from parallel to the epidermis at the base of the lesion to perpendicular at the summit of the porokeratotic column. The central core of the cornoid lamella consisted of a tightly packed mass of keratin.