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Biomedical subjects

C Debernardi

Publications and source records attributed to C Debernardi.

At least 19 recordsLinked to original sources

Reproducibility of surface EMG variables in isometric sub-maximal contractions of jaw elevator muscles.

The aims of this study were: (1) to develop and assess reproducibility of a new method for measuring masticatory force in the intercuspal position; (2) to test the reproducibility of surface EMG signal amplitude and spectral variables in constant force contractions of jaw elevator muscles and its dependency on inter-electrode distance. The study was performed on the masseter and temporalis anterior muscles of both sides of nine healthy volunteers. An intraoral compressive-force sensor was used to measure maximal voluntary contraction forces in the intercuspal position and to provide a visual feedback on sub-maximal forces to the subject. Three experimental sessions were performed in three days. In each session, three isometric contractions at 80% of the maximal force were sustained by the subjects for 30s. The intra-class correlation coefficient (ICC) of the maximal force measure was 71.9%. ICC of average rectified value and mean power spectral frequency of the EMG signal increased with inter-electrode distance, with values larger than 70% with 30 mm inter-electrode distance. It was concluded that surface EMG variables measured in isometric contractions of the jaw elevator muscles with the proposed force recording system show good reproducibility for clinical applications when a 30 mm inter-electrode distance is considered.

Adult↗

Non-invasive assessment of motor unit anatomy in jaw-elevator muscles.

The estimation of fibre length in jaw-elevator muscles is important for modelling studies and clinical applications. The objective of this study was to identify, from multi-channel surface EMG recordings, the main innervation zone(s) of the superficial masseter and anterior temporalis muscles, and to estimate the fibre length of these muscles. Surface EMG signals were collected from 13 subjects with a 16-electrode linear array. The innervation zones of the masseter and anterior temporalis were identified and their variability intra- and inter-subject outlined. More than one main innervation zone location was identified in the masseter of all subjects and in the temporalis anterior of 12 subjects. Average estimated fibre lengths, for the right (left) side, were (mean+/-SD) 27.3+/-2.4 mm (27.0+/-1.7 mm) and 25.9+/-2.3 mm (26.6+/-1.6 mm), for the superficial masseter and temporalis anterior muscle, respectively. The range of innervation zone locations was up to approximately 50% of the fibre length, both within and between subjects. Fibre length estimates well matched with published data on cadavers. It was concluded that multi-channel surface EMG provides important and reliable information on the anatomy of single motor units in jaw-elevator muscles.

Adult↗

Coronally advanced flap with or without enamel matrix derivative for root coverage: a 2-year study.

AIM: The purpose of this study was to assess the ability of enamel matrix derivative (EMD) to improve root coverage with a coronally advanced flap (CAF) during a 2-year follow-up. METHODS: Fifteen patients each with two single and similar bilateral Miller Class I or II gingival recessions (30 recessions) were selected. Each recession was randomly assigned to the test group (CAF+EMD) or the control group (CAF only). Clinical parameters recorded at baseline and at 6, 12 and 24 months were recession depth (R), recession width (WR), probing depth (PD), clinical attachment level (CAL) and keratinized tissue (KT). RESULTS: Reduction of R resulted in a significant CAL gain in both groups, whereas PD was not altered. In the test group, R decreased from 4.07 mm (SD+/-0.59) at baseline to 0.47 mm (SD+/-0.74) at 24 months, corresponding to a mean root coverage (MRC) of 90.67%, whereas in the control group R shrank from 4.13 mm (SD+/-0.74) at baseline to 0.60 mm (SD+/-0.83) at 24 months (MRC=86.67%). Complete root coverage was achieved at 24 months in 73.33% and 60% of the two groups. A significant KT increase was observed in both groups. CONCLUSIONS: Root coverage outcomes were similar in both groups and no statistically significant differences were found at all between them. Hence, the additional use of EMD to CAF is not justified for clinical benefits of root coverage, but as an attempt of achieving periodontal regeneration rather than repair.

Adolescent↗

Treatment of wide, shallow, and predominantly 1-wall intrabony defects with a bioabsorbable membrane: a randomized controlled clinical trial.

BACKGROUND: The regenerative therapy of non-contained intrabony defects achieves better results when bioabsorbable membranes are combined with a filling material. The purpose of the present study was to analyze clinical and radiographic effectiveness of a space-making bioabsorbable membrane in the treatment of wide and shallow intrabony defects characterized by a relevant 1-wall component. METHODS: Eighteen pairs of angular bone defects were selected in 18 healthy, non-smoking patients (age range 30 to 66 years). Prior to the surgical phase, patients were enrolled in a strict periodontal program including oral hygiene instructions and scaling and root planing (presurgical full-mouth plaque score <10%). Using a split-mouth design, 18 sites were randomly assigned to receive guided tissue regeneration (GTR) using a bioabsorbable membrane (test group) and 18 to receive open flap debridement alone (control group). Clinical treatment outcome was evaluated 12 months postoperatively for changes in probing depth (PD), clinical attachment level (CAL), and position of gingival margin (REC) and radiographically for bone changes. RESULTS: Open flap debridement and GTR yielded statistically significant (P<0.0001) PD reduction (2.39+/- 0.92 mm and 3.44+/- 0.78 mm), CAL gain (1.50+/- 0.99 mm and 2.89 +/- 0.90 mm), increased REC (-0.89 +/- 0.58 mm and -0.56 +/- 0.92 mm) and bone fill (1.05+/- 0.94 mm and 2.13+/- 1.21 mm) when 12-month data were compared to baseline. The differences between test and control groups were statistically significant for all parameters (P<0.007) except for REC (P=0.25). CONCLUSION: The use of this bioabsorbable membrane would seem to be effective in the treatment of intrabony defects with unfavorable architecture without the use of filling materials.

Absorbable Implants↗

Non-surgical periodontal therapy of cyclosporin A gingival overgrowth in organ transplant patients. Clinical results at 12 months.

AIM: The aim of the present study was to evaluate the clinical effects of non-surgical and supportive periodontal treatment on cyclosporin A-induced (CsA) gingival overgrowth (GO) in a group of transplant patients. METHODS: Thirty patients received etiological periodontal treatment and were placed in a -two-monthly recall program for 12 months. Plaque index, bleeding index, probing depth, degree of GO using the Seymour index (hypertrophy index, HI) and distance between the mucogingival junction and the base and the apex of each interdental papilla were recorded at baseline and repeated 12 months after treatment. RESULTS: At baseline, 22 patients had HI values >30% and were considered as ''responders''. A total of 376 gingival units (72.31%) in the anterior segments and 376 (54.97%) in the posterior ones presented GO with a mean HI value of 2.22 +/- 1.95 and 1.24 +/- 1.57, respectively. The etiological treatment resulted in a statistically significant improvement of all parameters assessed (P<0.0001). All patients had a decrease in the number of affected sites (mean HI values of 0.42 +/- 0.77 and 0.39 +/- 0.85 in the anterior and posterior segments) and none had HI values >30% and any gingival unit with score of 5 at the end of the observation period. CONCLUSIONS: Detailed instructions and intense motivation to oral home hygiene measures, inserted in an etiological treatment and a two-monthly maintenance therapy, appear to be effective in controlling the GO and in maintaining clinical improvements for prolonged time period.

Adult↗

Electromyographic evaluation of neuromuscular co-ordination during chewing in a subject with organic occlusion.

The neuromuscular co-ordination of the anterior masseter and temporal muscles during chewing has been studied. The subject analysed was 24 years old female with organic occlusion, molar and canine class 1, with 2 mm overbite and overjet, frontal disocclusion and canine protection, with no cranio-mandibular disorders. Masticatory cycles and electromyographic activity were recorded with a K6 I kinesiograph (Myotronics Inc., Seattle, WA, USA). The chewing cycles were recorded with a soft bolus and a hard bolus, on 3 consecutive days. Electromyographic analysis during masticatory cycles showed that electromyographic activity was higher in the masseter muscle homolateral to the chewing side than in the contralateral muscle, whereas the anterior temporal muscles achieved similar voltages. When chewing the hard bolus, versus the soft bolus, activity in the contralateral masseter muscle increased to a greater extent than in the homolateral masseter muscle. The results were analogous at all 3 recordings. When chewing, the subject showed good muscle co-ordination, which was constant over the 3 recordings made on 3 consecutive days. Increased activity of the contralateral masseter muscle when chewing the hard versus the soft bolus indicates the stomatognathic system's capability to adapt to load and its neuromuscular equilibrium.

Adult↗

Treatment of mandibular class II furcation defects by the use of amelogenins and autologous bone. Two case reports.

The aim of this preliminary study was to evaluate the clinical effectiveness of the association of amelogenins and autologous bone graft in the management of mandibular class II furcation defects. This randomized case-controlled study was conducted on 2 patients who presented 2 contralateral mandibular buccal class II furcation lesions. One defect was treated by amelogenins and autologous bone graft (test site) and the other one by open flap debridement (control site). At baseline and at 12 months postoperatively, the full-mouth plaque score (FMPS) and the full-mouth bleeding score (FMBS), the probing depth (PD), the clinical attachment level (CAL) and the recession (REC) were recorded and a periapical radiograph of the selected area was taken. In addition, at 12 months a surgical re-entry was performed. Test sites had a greater horizontal PD reduction and radiographic bone filling compared to control sites. None of the treated sites achieved complete furcation closure. At the time of re-entry, furcations treated by amelogenins were partially filled by newly formed not soundable hard tissue, while furcations treated by conventional flap surgery were filled by epithelial and connective tissue. These findings suggest that the treatment of mandibular class II furcations by amelogenins and autologous bone graft may result in a significant clinical improvement. Further long-term studies conducted on a larger sample size are therefore needed to confirm our results.

Amelogenin↗

Perceptibility of condylar displacement through transcranial radiographs and split-cast technique on dry skull.

The authors compared the limit of perceptibility of transcranial radiographs and of the split-cast technique in detecting differences in condylar position. The study was carried out on two dried human skulls. The results indicated the split-cast method was superior to the radiographic method as it allowed differences in condylar position of 0.2 mm, both in sagittal and frontal plane, to be detected. The limit of perceptibility of transcranial radiographs for position differences in the sagittal plane was 0.6 mm for naked-eye examination and 0.2 mm when using the subtraction method. Differences in condylar position even as large as 0.6 mm in the frontal plane could not clearly be seen by naked-eye examination, and with the subtraction technique only if they were of at least 0.4 mm.

Humans↗

[AIDS and pedodontics: the real risk and its prevention].

The daily increase in carriers of the AIDS virus (150,000 is the latest estimate for Italy) means that the dentist must pay the utmost attention in selecting cases at risk and in defending himself from the possibility of contagion. Albeit to a lesser extent, the pedodontist is also involved in this problem. Here situations in which the risk of contagion is greatest because of the patient's social position or associated pathologies and the difficulty of the operation required are reported and some indications are offered to guide the pedodontist's professional behaviour.

AIDS-Related Complex↗

[Professional, criminal and civil responsibility and the legal medical aspects of the performance of the dentist practicing local anesthesia and tooth extractions].

The paper affirms that the dentist can come up against severe complications while exercising his profession which expose him to charges outlined by the Penal and Civil Codes. The circumstances in which the operator's responsibility can be questioned during the use of local anesthesia and extraction are discussed.

Anesthesia, Dental↗

[334 cases of salivary gland neoplasms seen at the Dentistry and Otorhinolaryngology Clinics of the University of Turin. II].

Three hundred and thirty-four cases of salivary gland neoplasms are reported which were diagnosed by the Departments of Dentistry and Otolaryngology of the University of Turin. Data referring to patients under observation during the same period are compared. It is stressed that in order to obtain a statistically valid comparison of salivary gland neoplasms, the source of and chronological period relating to the sample group must be taken into consideration given the different statistical clinical methods adopted over the years by the two departments in question. The present study completes earlier research carried out by the same authors using this data.

Age Factors↗

[The use of Josamycin in dental pathology].

Authors evaluated the clinical results of the use of Josamycin in odontostomatology. The clinical trial has been carried out on 42 patients with acute bacterial infections. Josamycin appeared a very safe and effective antibiotic.

Adult↗

[Histopathological considerations on 8 cases of mixed tumors or pleiomorphic adenomas of the salivary glands].

In view of the problems sometimes presented in diagnosing mixed tumours or pleomorphous adenomas of the salivary glands, the histopathological pictures of eight personal cases are considered. The epithelial component is found in solid masses, or arranged in cords or has an adenomatous appearance. Two cases presented a cylindromatous-like appearance which called for greater diagnostic attention and led to a more attentive postoperative clinical control.

Adenoma, Pleomorphic↗

[Hereditary type enamel hypoplasia. Clinical and histopathological findings of an observed case].

The main classifications published in recent years on amelogenesis imperfecta are reported and the ways in which abnormal enamel can be formed are described. A personal case is reported in which it was possible to draw up a family tree and document clinical and histological histories. The anomaly was classified in the hypoplasia group, rough, autosomic dominant according Witkop and Sauk.

Amelogenesis↗

[392 cases of neoplasms of the salivary glands seen at the Odontostomatologic and Otorhinolaryngologic Clinic of Turin University. I].

Three-hundred-ninety-two cases of salivary gland cancer observed at Turin University Dental and Ear, Nose and Throat Clinics have been examined. Statistical analysis of the age and sex of patients shows the importance of selecting the statistical population and of its origin for the purpose of reliable statistical study, examining the whole set and its structural breakdown in the two Clinics.

Adolescent↗

[Macroglossia. Considerations on a case load of 16 patients].

The Authors have examined sixteen cases of macroglossia and after hinting at the various causes they dwell upon clinic and therapeutic problems presented by patients. From the analysis of individual cases it results that muscular idiopathic hypertrophy is the most recurrent cause of macroglossia. It is furthermore emphasized the relation between macroglossia and occlusal disharmony. The kinds of therapy used and compared are two: surgical and orthodontic.

Adolescent↗