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C Debernardi

Publications and source records attributed to C Debernardi.

At least 37 records · Page 2Linked to original sources
PubMedDate not supplied

Debridement and local application of tetracycline in the management of persistent periodontitis. Clinical and microbiological results after 12 months.

AIM: The purpose of this study was to evaluate the clinical and microbiological efficacy of local delivery of tetracycline in persistent periodontal lesions after topical therapy. METHODS: A total of 44 bilateral pockets 4-5 mm deep and bleeding on probing were selected in 11 non-smokers patients, 22 treated by scaling and root planing plus tetracycline fibres (test sites) and 22 with scaling and root planing alone (control sites) in a split-mouth design. Bleeding on probing, probing depth and clinical attachment level were recorded at baseline, 6 and 12 months postoperatively. The prevalence of Actinobacillus actinomycetemcomitans, Porphyromonas gingivalis, Prevotella intermedia, Bacteroides forsythus and Treponema denticola was monitored by PCR at baseline, fibres removal, 6 and 12 months following treatment. RESULTS: The improvements in clinical parameters were greater in the tetracycline than in the control group. The reduction of bleeding on probing scores was 86.4% and 40.9%, the decrease of probing depth was 2.25 mm and 1.19 mm and the gain of clinical attachment level was 2.04 mm and 0.64 mm for test and control groups, respectively, over the 12-month period. The adjunctive use of tetracycline consistently resulted in a lower percentages of sites with detectable levels of A. actinomycetemcomitans, P. intermedia and P. gingivalis, while no differences were detected between treatments in the prevalence of T. denticola and B. forsythus. The pathogens could be eliminated from 3 periodontal pockets by debridement alone and from 12 sites by tetracycline at 12 months. CONCLUSIONS: Tetracycline local delivery gave the greatest advantage in the long-term treatment of periodontal persistent lesions.

Administration, Topical↗
PubMedDate not supplied

[General complications of local anesthesia in dentistry: prevention and therapy].

The general complications of local anaesthesia in odontostomatology are reviewed and pathogenesis and symptomatology described. Mention is then made of prevention and treatment. Conclusions refer observation in more than 150,000 cases of local anaesthesia, a line of conduct being suggested to prevent complications, from the simplest to the most complex, and consequently medico-legal responsibilities for the specialist.

Anaphylaxis↗
PubMedDate not supplied

[Melanocytes in the epithelium of the gingival mucosa in different conditions of edentia].

Gingival crest melanocytes were examined in partial and total edentulates (with and without prostheses). Where the epithelium showed signs of epidermisation, the cells displayed their normal form and melanogenetic activity. In the presence of involution (acanthosis, reduction of the surface layers, smallcell infiltration), they withdrew their typical cytoplasmic expansion, while the Dopa reaction revealed poor thyrosinase activity. It is felt that these patterns confirm the epithelio-melanocyte symbiosis theory put forward by Quevedo et al. One total edentulate with a mucosally supported prosthesis displayed Dopa-positive dendritic cells on the gingival corium and tunica propria. These are seen as true melanocytes that had migrated from the epithelium.

Adult↗