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Biomedical subjects

C Desaive

Publications and source records attributed to C Desaive.

At least 91 records · Page 5Linked to original sources
PubMedDate not supplied

[Surgical treatment of incarcerated inguino-crural hernia with interposition of a preperitoneal prosthesis].

For the last four years, 17 inguinal and femoral strangulated hernias have been treated at our institution by a median subumbilical incision. In all cases, a prosthesis has been placed by preperitoneal approach. An intestinal resection for irreversible necrosis has been performed in five patients. This procedure gives good control of the herniated organs, allows easy intestinal resection and good management of unforeseeable situations. The surgical exploration of the other hernial orifices and, if needed, their simultaneous treatment can be performed. Intestinal resection does not represent, in our opinion, an absolute contra-indication to the implantation of a prosthesis. In our study, the morbidity does not seem to be increased.

Adult↗
PubMedDate not supplied

[Results of a policy of conservative treatment of breast cancer (146 cases)].

Tumorectomy and irradiation for small cancer of the breast. Tumorectomy followed by breast irradiation and a single course of chemotherapy is the most accurate treatment for small cancer of the breast. The 5 and 10 years survival are 92.5% and 85% respectively: this demonstrates the efficacy of the conservative treatment in the control of most of the small breast cancer provided a strict selection of the cases was done. Patients who develop local recurrence have the same life expectancy than the other cases when they are soon treated by mastectomy.

Breast Neoplasms↗
PubMedDate not supplied

[Value of radioimmunological serum levels of carcinoembryonic antigen in the postoperative monitoring of rectocolonic cancer].

Fifty four patients, operated for colorectal cancer have been followed up for 2 to 100 months after surgery by carcino-embryonic antigen (CEA) determinations and classical, clinical, biological, radiological, echographical, isotopical and tomoscanninvestigations. Each new serum sample has been assayed for CEA with previously collected samples within the same patients. This repetition of CEA on the same samples allows to check the good reproducibility of CEA radioimmunoassay (variation coefficient between assay is less than 10%) and to get a complete profile of CEA level evaluation within the same assay. There is a good correlation between clinical evolution and CEA levels. In 42 patients, CEA levels remained or became normal (less than 10 ng ml) after surgical resection of the tumors and no metastasis or local recurrence were detected. In 12 cases, CEA levels remained or became abnormally high (greater than 20 ng ml) at the same time or before clinical and/or paraclinical evidences for metastases or local recurrence. These results showed CEA assay in a quantitative parameter to assess the follow-up of colorectal cancer complementary to clinical, biological, radiological, echographical and isotopical criterias.

Adenocarcinoma↗
PubMedDate not supplied

[Malignant lymphoma complicating Crohn disease of the ileum. Apropos of a case].

The association of cancer and Crohn's disease is well documented and comprises 2% of cases, but the onset of a malignant lymphoma during the course of the disease is a very rare finding (20 cases reported). A patient presented with a malignant plasmocytic lymphoma complicating an ileal Crohn's affection. Both clinical and radiological diagnosis were uncertain, most such cases being discovered perioperatively, confirmation of the diagnosis being provided by histology and immunohistology, which also allow classification of the lymphoma to allow adaptation of complementary postoperative treatment.

Aged↗
PubMedDate not supplied

Use of an absorbable polyglactin mesh for the prevention of incisional hernias.

Nowadays, incisional hernias are still one of the more common complications of abdominal surgical procedures. A population, at high risk of developing an incisional hernia, has been chosen for this study, namely patients suffering from morbid obesity. The aim of the study was to compare prospectively the incidence of incisional hernias in 2 groups of patients operated upon for morbid obesity (Vertical Silicone Ring Gastroplasty) with or without intraperitoneal polyglactin mesh. Patients were randomly assigned in the 2 groups. For this preliminary study, 112 patients operated upon before 01/04/1992 were selected; the mean follow-up period was 28.3 months (S.D.:5.7); 81 patients have been reviewed personally, 31 interviewed by phone call or mail. The 2 groups of patients were not significantly different as regarding age, sex, weight, body mass index, diabetes and wound infection. Sixteen incisional hernias were observed in the group with mesh and 17 in the group without mesh. According to these preliminary results, there is no argument for recommending the use of the polyglactin mesh in the prevention of postoperative incisional hernias, in obese patients.

Adult↗