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Biomedical subjects

C Desaive

Publications and source records attributed to C Desaive.

At least 73 records · Page 4Linked to original sources
PubMed1975

Mode of action of amphotericin B on chick embryo fibroblasts and on mouse Ehrlich tumour cells: a cytological and cytochemical analysis.

Chick embryo fibroblasts cultivated in vitro and Ehrlich ascites tumor cells (in vivo or in vitro) have been treated with amphotericin B. Cell multiplication is strongly inhibited. Large clear zones appear in the fibroblast nucleoi (phase-contrast and electron-microscope observations). Many treated fibroblasts and tumour cells have a high DNA content (pre-mitotic or polyploid level; measurements by cytophotometry). However, the RNA content (cytophotometry) and the total protein content (cytophotometry and micro-interferometry) are relatively low in the tumour cells. As shown by autoradiography, DNA synthesis is active but RNA synthesis and, in some cases, protein synthesis are inhibited. Due to this unbalanced growth, the cells cannot divide.

Amphotericin B↗
PubMed1975

[Importance of arteriography in the diagnosis of splenic trauma (author's transl)].

Among 26 cases of suspected hemorrhage the authors report 8 cases of splenic trauma. They note perfect agreement between the importance of the radiological lesions and the seriousness of the clinical signs. Given the harmlessness of the investigation and the frequency of the visceral lesions it disclose, the authors recommend arteriography in difficult cases with subacute or chronic evolution.

Angiography↗