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Biomedical subjects

C Dudok de Wit

Publications and source records attributed to C Dudok de Wit.

At least 19 recordsLinked to original sources
PubMed1990

[Revised definition of the concept rhesus-negative blood donor; practical experiences].

In 1987 the Central Medical Blood-transfusion Committee of the Netherlands Red Cross decided to modify their definition of 'Rh-negative' as it applied to blood donors. Until then the term Rh-negative had been reserved for donations that grouped as C- and E-negative and failed to react with IgG anti-D by the indirect antiglobulin test (IAT). From June 1987, however, donations were considered to be Rh-negative if they failed to react with two strong anti-D sera. An evaluation is presented over the first one and a half years of working with the new definition, the problems that were encountered and the measures that are taken to guarantee the quality of Rh testing.

Blood Banks↗
PubMed1968

Prevention of rhesus immunization. A controlled clinical trial with a comparatively low dose of anti-D immunoglobulin.

A controlled clinical trial was carried out to test the effectiveness of a comparatively low dose of anti-D immunoglobulin (250 mug) in preventing rhesus immunization.In the control group 17 out of 329 women (5%) formed rhesus antibodies, whereas in the treated group only 3 out of 333 women (0.9%) showed active immunization, all three of whom had an exceptionally large transplacental bleeding.

Antibody Formation↗