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Biomedical subjects

C Fava

Publications and source records attributed to C Fava.

At least 19 recordsLinked to original sources

[Percutaneous transjugular intrahepatic portosystemic shunt (TIPS). The preliminary experience and proposal of a new method].

A new interventional procedure employing metallic stents has been recently suggested to perform percutaneous portosystemic shunts in the treatment of variceal bleeding in portal hypertension; the technique is called TIPSS (transjugular intrahepatic portosystemic stent shunt). This percutaneous treatment presents several advantages over surgery: the shunt diameter can be calibrated according to the degree of portal hypertension; moreover, TIPSS can be performed in patients waiting for liver transplantation because it does not alter the vascular anatomy of liver. The original technique employed transhepatic portography. In this paper the authors report on their personal experience and present their series of 4 patients with portal hypertension and variceal bleeding, in whom TIPSS was performed utilizing noninvasive US guidance. Variceal bleeding was successfully treated in all patients and variceal distension was also obtained.

Adult

[Percutaneous transcatheter embolization of deep visceral pseudoaneurysms].

The authors present their experience with the percutaneous embolization of 13 splanchnic aneurysms and pseudoaneurysms (2 pseudoaneurysms of gastroduodenal artery, 3 of the hepatic artery, 7 renal pseudoaneurysms, 1 aneurysm of the splenic artery). In 9 of 13 cases the lesions were iatrogenic. Embolizing devices and techniques are described. Percutaneous embolization was successful in 12 of 13 cases, and useless in 1 case of renal pseudoaneurysm. In the 12 successfully treated cases the lesions were still occluded in the follow-up period. Transcatheter percutaneous embolization is the elective treatment in splanchnic aneurysms and pseudoaneurysms; surgery must be performed only when embolization fails.

Adult

Combined evaluation of total and functional liver plasma flows and intrahepatic shunting.

A diagnostic protocol was studied, designed to evaluate the main parameters of liver circulation in man. A water solution of D-sorbitol (S) and indocyanine green (ICG) was infused intravenously in six controls and nine cirrhotics. Steady-state renal and hepatic S clearances as well as hepatic ICG clearance were calculated. In controls the values (mean +/- SD) of the independent measurements of S and ICG hepatic clearance were 978 +/- 107 and 519 +/- 142 ml/min, respectively, while in cirrhotic patients they were 554 +/- 238 and 231 +/- 90 ml/min. Owing to the kinetic properties of S, its hepatic clearance may be regarded as a measure of functional liver plasma flow (FLPF). The total liver plasma flow (TLPF) values (mean +/- SD), calculated according to Fick's principle, were 1091 +/- 157 ml/min (S method) and 1033 +/- 153 ml/min (ICG method) in controls, and 1251 +/- 554 and 1284 +/- 677 ml/min in cirrhotics. In controls, FLPF was found to be very close to TLPF. In cirrhotic patients the difference between TLPF and FLPF (ranging from 169 to 2093 ml/min when measured by S method) was considered as an approximate estimate of intrahepatic shunting. The procedure is safe and simple and may add a new dimension to the investigation of hepatic circulation.

Adult

Radiologic-prosthetic planning of the surgical phase of the treatment of edentulism by osseointegrated implants: an in vitro study.

An original prosthetic planning involving CT scan is described; it provides the surgeon with a template for use during the surgical phase of osseointegrated implant treatment. The final prosthodontic reconstruction was planned in a preliminary in vitro study. The CT scan provided a three-dimensional study of the underlying bone, to determine the position, angulation, and depth of the fixture to be used. The specially developed "positioner" decreased the possibilities of error in perforating the mandible. A second CT scan verified whether there were errors in positioning the fixtures. The satisfactory results and the predictability of the final rehabilitation led to the adoption of this method in a clinical research program on human patients.

Dental Implantation, Endosseous

[Percutaneous unblocking of porto-systemic shunts. Personal experience with 11 cases].

The authors report their personal experience in percutaneous treatment of portosystemic shunt occlusion and stenosis. Eleven patients with portosystemic shunt stenosis or occlusion were percutaneously treated. Seven patients were treated with PTA alone; in 2 cases, with recurrent variceal bleeding, percutaneous variceal embolization was associated with PTA. Four patients were treated with local fibrinolytic infusion through the catheter inserted into the thrombus; in 3 cases this treatment was followed by PTA. In all 11 patients recanalization was possible, no complications arose. Six patients died in the following 15 months, none due to rebleeding; in 5 patients of this group the shunt was patent at autopsy. In one patient autopsy was not performed but the shunt was functioning at the last duplex US control. Of 5 patients still alive in the follow-up period (2-25 months) the shunt was patent in 3 and occluded in 2.

Adult

Lateral transcranial radiography of temporomandibular joints. Part II: Image formation studied with computerized tomography.

Two series of radiographs of 15 subjects (30 TMJs overall) were compared in order to evaluate the reliability of OLTP carried out with different techniques: individualization of incidence through radioscopy (OLTP/fluo) or through the submental vertex method (OLTP/sub). Reasons for formation of noninterpretable radiographs (prevalently with OLTP/sub) and for diagnostic errors in judging condyle position were evaluated for each technique through a CT scanning study of the same patients. The reasons for the wide range of constancy of results found in OLTP/fluo are also discussed. Overall the study demonstrated reliability of the OLTP carried out with the technique of individualizing the incidence through fluoroscopy.

Humans

Lateral transcranial radiography of temporomandibular joints. Part I: Validity in skulls and patients.

Left and right TMJs of 10 skulls and 15 patients (50 TMJs) were studied by means of OLTP and tomography to establish optimal condylar position in the glenoid fossae at maximum dental intercuspation. Two OLTP examinations of each joint were made and individualized by submental X ray and by fluoroscopy. A comparison of the recorded data showed fluoroscopy to give the better result. According to this study, OLTP individualized by fluoroscopy may be a useful tool in the determination of condylar position.

Adolescent

[Percutaneous biopsy (PB) of solid thoraco-abdominal formations with instrumental guidance. The authors' experience].

The results are reported of 283 percutaneous biopsies performed on solid thoracic and abdominal masses. Indications to biopsy are examined at first, which are relatively limited in number if compared to other authors' opinion on the subject--i.e., when the tumor cannot be characterized with any other methodology, or in case of neoplasms whose histological type is to be known in order to plan therapy. The techniques employed are then evaluated, with a special emphasis on the needle caliber and the guidance method (US, radioscopy and CT). Correct samplings have been obtained in more than 90% of cases. Minor complications were observed in less than 10% of cases, while major complications were totally absent. In conclusion, percutaneous biopsy proves useful in those cases where exam indication is respected and an accurate selection is previously performed.

Abdomen