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Biomedical subjects

C Fox

Publications and source records attributed to C Fox.

140 records · Page 8Linked to original sources
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Perceptions of tissue viability nurses of their current roles.

This qualitative and quantitative study was undertaken on a national scale. It identifies the perception of the role of the tissue viability nurse by its incumbents through the circulation of postal questionnaires sent to 173 identified tissue viability nurses, of which 87 responded. A constant comparative analysis of the responses identified the repetitive phrases and key words for the qualitative data. The quantitative responses were facilitated through the use of closed questions. The research facilitated four areas of discussion: role overview; perceived levels of education; positive/negative aspects of the role; types of wound contact and reasons.

Attitude of Health Personnel↗
PubMedDate not supplied

Consumer views of pressure sores: a preliminary survey.

AIM: To obtain consumer views about pressure sore development, particularly in A&E departments. METHOD: The local Patient and Carers Association received a freepost survey in the form of a simple fixed choice questionnaire. RESULTS: Fewer than half the questionnaires were returned. Relatively few respondents were aware that pressure sores could be avoided, and few were aware that prolonged bed rest or lying on a hospital trolley could increase the risk. CONCLUSION: The survey raised more questions than it managed to answer. More research is needed into the views of patients and carers before they can be involved in healthcare planning.

Emergency Nursing↗
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Advice shop.

Explore the source record for details and available documents.

Aged↗
PubMedDate not supplied

Enhancement of recall of cardiopulmonary resuscitation (CPR): Use of moving-image card to review the dynamics of CPR.

Since victims of cardiac arrest have a more favorable outcome when CPR is immediately applied, it is important to continue to motivate individuals to learn proper technique. It is equally important to ensure that individuals who have learned CPR maintain adequate recall of the procedure. With the intent of enhancing recall of the principles of CPR, a wallet-size plastic card was developed which, when tilted, creates the illusion of movements. Thus, the card enables a viewer to review the dynamic aspects of CPR and reinforces the essential steps of establishing an airway and maintaining breathing and circulation.

Heart Arrest↗
PubMedDate not supplied

The timing of skin acidification in very low birth weight infants.

OBJECTIVE: The purpose of this study was to examine the development of the pH mantle of the skin in very low birth weight (VLBW) infants. STUDY DESIGN: Forty VLBW infants underwent repeated measurements of skin pH over the first month of life using a glass flat-surface pH electrode. Six skin sites were measured, daily for the first week of life and then twice weekly for the next 3 weeks. RESULTS: The only factor that affected the initial skin pH was sex, with males having a significantly higher pH at birth. Over time, birth weight, skin area, and postnatal age had significant effects on skin pH. The pattern of postnatal change in skin pH was similar to that described in term infants, a rapid decrease in pH over the first week followed by a more gradual decrease over the next 3 weeks. CONCLUSION: The development of the skin's acid mantle in VLBW infants occurs rapidly during postnatal life and closely mimics the pattern seen at term.

Birth Weight↗
PubMedDate not supplied

Quantification of cathepsin D in plasma of patients with malignant melanoma.

The high mortality rate of melanoma patients who develop metastases prompted us to seek for a prognostic soluble marker to identify high-risk and non-risk patients at the stage of the primary tumour. Therefore, we developed a new ELISA for quantifying plasma concentrations of the proteolytic enzyme cathepsin D (CD) in patients with primary tumours (MM-P) and with metastases (MM-M), respectively, compared to a control group. Whereas healthy probands (n = 56) and MM-P (n = 68) showed similar mean values of CD (0.73 +/- 0.45 ng/ml and 0.82 + 0.80 ng/ml), MM-M (n = 40) yielded significantly reduced plasma levels (0.43 +/- 0.53 ng/ml) revealing a high significant discrimination both between controls and MM-M, and MM-P and MM-M (p < 0.0001). From the beginning of the study (1990) to the present 11 of 68 MM-P developed metastases. In order to test the prognostic efficiency of this enzyme to determine those patients at high-risk and non-risk for developing metastases, the receiver operating characteristic analysis was used showing that CD plasma levels cannot supply reliable prognostic values (W = 0.53, p = 0.66).

Adult↗
PubMedDate not supplied

Soluble HLA class I antigens in plasma of patients with malignant melanoma.

The high mortality rate of melanoma patients who develop metastases prompted us to look for prognostic markers to determine high-risk and non-risk patients at the primary tumour stage. Therefore, we quantified plasma concentrations of soluble HLA class I antigens (sHLA-I) by ELISA in patients with primary tumours (MM-P) and with metastases (MM-M), respectively, and compared them to a control group. Whereas healthy probands (n = 55) and MM-M (n = 38) showed similar mean values of sHLA-I (1.30 +/- 1.44 micrograms/ml and 1.29 +/- 1.27 micrograms/ml), MM-P (n = 67) revealed significantly reduced levels of this marker (0.84 +/- 0.85 microgram/ml). This result matches with our immunohistological staining of membrane-bound HLA-I in sections of paraffin-embedded melanoma. Further subdivision of the MM-P substantiated the observation that mean values of decreased sHLA-I concentrations are in line with high tumour thickness. Since the beginning of this study (1990) to date, 11 of 67 MM-P have developed metastases. The prognostic efficiency of sHLA-I to identify high-risk and non-risk patients was tested by ROC-analysis (receiver operating characteristic) and did not demonstrate good prognostic relevance for sHLA-I (W = 0.64, p = 0.04).

Adult↗
PubMedDate not supplied

The effects of guided imagery on comfort of women with early stage breast cancer undergoing radiation therapy.

PURPOSE/OBJECTIVES: To measure the effectiveness of customized guided imagery for increasing comfort in women with early stage breast cancer. DESIGN: Experimental longitudinal, random assignment to groups. SETTING: Two urban radiation oncology departments. SAMPLE: 53 women (26 in the experimental group, 27 in the control group) aged 37-81; 80% European and 10% African American with stage I or II breast cancer about to begin radiation therapy. METHODS: The experimental group was to listen to a guided imagery audiotape once a day for the duration of the study. The Radiation Therapy Comfort Questionnaire was self-administered at three time points: prior to the introduction of intervention and the beginning of radiation therapy (Time 1), three weeks later (Time 2), and three weeks after completing radiation therapy (Time 3). The State Anxiety Inventory was administered at Time 1 only. MAIN RESEARCH VARIABLES: The effect of use of guided imagery on comfort with anxiety as a control variable. FINDINGS: Pooled data indicated a significant overall increase in differences in comfort between the treatment and control group, with the treatment group having higher comfort over time. The data also revealed a significant linear trend in differences between groups. No significant interaction of group and time existed. CONCLUSIONS: Guided imagery is an effective intervention for enhancing comfort of women undergoing radiation therapy for early stage breast cancer. The intervention was especially salient in the first three weeks of therapy. IMPLICATIONS FOR NURSING PRACTICE: Guided imagery audiotapes specifically designed for this population were resource effective in terms of cost, personnel, and time.

Adult↗