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Biomedical subjects

C Fryze

Publications and source records attributed to C Fryze.

At least 37 records · Page 2Linked to original sources

[Neurological deficits in patients with primary and secondary anticardiolipin syndrome].

27 patients (22 women, 5 men); age 17 to 56 yr. (mean age 37 yr.) were included in this study, 4 had primary antiphospholipid syndrome and 18 secondary antiphospholipid syndrome in the course of systemic connective tissue disease and in 5 cases increased levels of anticardiolipid antibodies were found which did not meet the criteria necessary for diagnosis of secondary antiphospholipid syndrome. The mean duration of the disease was 8 yrs. Among primary antiphospholipid syndrome patients two had ischaemic stroke, one migraine-like headache and seizures. 18 patients had lupus erythematosus, two mixed connective tissue disease, one rheumatoid arthritis, one Sjögren syndrome, one Behçet disease. In 55% of patients migraine-like headache, polyneuropathies, encephalophaties, stroke, seizures and vision disturbances were present. In 18.5% of patients EEG exam revealed focal lesions with tendency for generalisation. On brain stem auditory evoked potentials examination, in 11.1% of patients conductivity lesions in mesencephalon and pons were found, visual evoked potentials, in 11.1% of patients in visual tracts. In 37% of patients, neuropathy was found on EMG exam. Neurological symptoms are one of the most frequent disorders in systemic connective tissue disease associated with the presence of anicardiolipin antibodies.

Adolescent↗

[Physiologic all-night sleep in patients with severe forms of epilepsy].

100 all night sleep records in 90 patients with various forms of epilepsy and 10 patients with syncope were analyzed. There were 10 patients with generalized epilepsy, 41-with partial epilepsy with complex symptomatology and temporal foci, 23--with mixed seizures and frontal focal changes and 16 patients with partial epilepsy with simple seizures and various location of EEG foci. Normal sleep pattern was present in 21% of cases. The most frequent changes of sleep pattern were: prolongation of sleep onset and the latency of the first episode of REM, instability of sleep stages and absence of sleep spindles. Interictal discharges appeared mostly in all sleep stages of NREM. 50% of epileptic patients showed focal spikes in REM. Nocturnal seizures occurred in 18 patients, in several of them very frequently.

Adolescent↗

[Catamnestic studies of patients with reversible ischemic stroke].

The authors carried out follow-up examinations of 75 patients with reversible ischaemic strokes suffered by them 6-10 years earlier. The results showed that reversible ischaemic strokes accounted for about 8% of all strokes. The risk of a repeated stroke was about 10.6%. The prognosis in such cases is rather good, but is worsened by coexistence of risk factors, particularly by coincidence of several such factors. In 17.6% of cases death ensued within 6-10 years.

Adult↗

[Myoclonic cerebellar dyssynergia (Ramsay Hunt). Description of 2 cases].

The authors report two cases of dyssynergia cerebellaris myoclonica in siblings. Apart from typical clinical manifestations attention is called to the results of computerized tomography of the brain which demonstrated cerebellar atrophy. This helped in verification of the diagnosis. Comparing these cases with other ones described earlier in the literature the authors conclude that dyssynergia cerebellaris myoclonica is not a separate nosological entity but a syndrome associated with myoclonia.

Cerebellar Ataxia↗