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Biomedical subjects

C Fryze

Publications and source records attributed to C Fryze.

41 records · Page 3Linked to original sources

[Effect of different stages of physiological nocturnal sleep on interseizure discharges in patients with various forms of epilepsy].

All-night EEG records were obtained in 100 patients aged 14-48 years staying at a neurosurgical centre for various forms of focal epilepsy. In 84 cases discharges were observed during the nocturnal investigation. The morphology of the discharges depended on the phase of sleep during which they appeared. Discharges occurring in phases of light sleep had greater activity and more focal character in relation to the remaining NREM phases. On the other hand, discharges in deep sleep phases had a greater tendency for generalization. In half the cases focal discharges disappeared in the REM sleep phase. Intraseizure changes depended on the phase of sleep, focal or generalized character, and localization of pathological focus. Seiture activity during sleep was never observed in the REM phase of sleep.

Action Potentials↗

[Epileptic seizures and alcoholism].

A high incidence of epilepsy in chronic alcoholics and similar incidence of alcohol abuse in patients with epilepsy are a serious medico-social problems. A relation between seizures and alcohol abuse is discussed in this paper. Epilepsy is the commonest complication of an alcoholism. Pathogenesis of epileptic seizures is multiple and complex. Alcohol-dependent epilepsy is closely related to a problem of alcohol abuse in patients with epilepsy. A criteria of alcohol-dependent epilepsy diagnosis should be clearly defined as they play an important role in therapy selection.

Alcoholism↗

-The evaluation of the effectiveness and tolerance of sumatriptan in abortive treatment of migraine attacks (open multicenter trial).

The authors review data on sumatriptan obtained in the results of their own studies performed on 78 patients in 10 Polish neurological centres. In all 154 migraine attacks were treated with 6 mg of subcutaneous sumatriptan. Significant decrease of pain intensity was achieved in 30% of cases after 15 min and 60%--after 30 min. According to the patient's own opinion, 62% of them evaluated the drug as very efficient, 23% of patients--as efficient. Adverse effects were reported by 11 patients (15%), but they were mild and transient. Headache recurred in 16% of patients.

Adult↗