Biomedical subjects
C J Gilman
Publications and source records attributed to C J Gilman.
Management of early-stage endometrial carcinoma.
Endometrial cancer is now the most frequently diagnosed invasive gynecologic malignancy in the United States. The majority of patients are in the perimenopausal or postmenopausal age range, and many have coincidental medical problems that bring them under the care of the family physician. Most of the patients have Stage I or Stage II endometrial carcinoma and thus have an excellent opportunity for long-term disease-free survival.
Pion treatment procedures and verification techniques.
Procedures and techniques developed for the negative pi-meson (pion) radiotherapy program at the Los Alamos Meson Physics Facility, Los Alamos, NM, are reviewed and described. A particular pion patient is followed through the entire planning and treatment sequence to describe CT scanning procedures, bolus and collimator and treatment techniques developed to minimize positioning errors (less than 5 mm). Comparison of 2-D and 3-D isodose calculations developed at Los Alamos showed differences of less than 10% attributable to multiple scattering effects and the computational models used. Treatment verification methods using in vivo ion chamber dosimetry generally confirmed the prescribed dose delivery within 10% and using TLD within 18%.
Improving survival in patients with rectal cancer.
Adenocarcinoma of the rectum accounts for approximately 5 percent of new cancer cases and for an estimated 31 percent of new cases of colorectal cancer. Although surgical resection remains the treatment of choice for almost all cases of this disease, a significant number of patients will develop locoregional recurrence after surgery if no other treatment is given. Relatively modest doses of radiation may improve long-term survival and can prevent locoregional relapse after surgery in many high-risk patients.
Primary radiotherapy in early breast cancer.
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