Studies on the rate of diffusion-controlled reactions of enzymes. Spatial factor and force field factor.
Explore the source record for details and available documents.
Bicarbonates↗
Biomedical subjects
C Kuo-chen
Publications and source records attributed to C Kuo-chen.
The quantitative relations between diffusion-controlled reaction rate and characteristic parameters in enzyme-substrate reactions systems. II. Charged substrates.
The quantitative relationship between the spatial factor and the force-range factor on the one hand and the ionic strength and the charges of reactants on the other has been calculated for non-spherically symmetric reaction systems. New upper limits of combination reactions between enzymes and charged substrates have been obtained. Applying the calculated results to the reactions catalyzed by fumarase and D-glyceraldehyde-3 phosphate dehydrogenase, we have been able to interpret experimental phenomena which could not be accounted for by the conventional theory of the diffusion-controlled reaction. Furthermore, the conditions under which the Bronsted equation is valid in the non-equilibrium steady state reaction system have been discussed.
Binding Sites↗