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C L Benhamou

Publications and source records attributed to C L Benhamou.

81 records · Page 5Linked to original sources
PubMed1982

[Destructive arthritis and Behçet's syndrome].

The arthritis of Behçet's syndrome is not usually responsible for articular destructions, so that the presence of destructive lesions makes the diagnosis of Behçet's syndrome doubtful. Here is presented the observation of a 29 years old man (his illness beginning at twelve), with a typical Behçet's syndrome, who developed a destructive arthritis. Arthritic and systemic flares showed a parallel evolution. Destructive lesions involved wrists, hands, feet and elbows. The search for another cause of destructive arthritis (mainly juvenile rheumatoid arthritis and ankylosing spondylitis) was negative. The occurrence of destructive arthropathies in Behçet's syndrome has been exceptionally reported.

Adolescent↗
PubMed1981

[Porphyria].

Explore the source record for details and available documents.

Humans↗
PubMed1980

[Diffuse corticoid-sensitive cerebral arteritis (author's transl)].

Three cases of cerebral vascularitis are reported. This affection does not occur frequently and is often unrecognized. It can be isolated or associated with disease such as sarcoidosis, Behcet's disease, or collagen disorders (lupus erythematosus, mixed connective tissue diseases). Diagnosis is made from the evolution with transient remission, the inflammatory nature of the CSF, and the presence of segmentary narrowing on arteriography. In case of doubt an exploratory operation with biopsy is necessary. The most likely etiology is an auto-immune disturbance, and cortico-therapy has greatly improved the prognosis.

Adrenal Cortex Hormones↗
PubMedDate not supplied

[Efficacy, tolerability and therapeutic benefit of etodolac (Lodine 200) in rheumatologic practice].

Efficacy, safety and therapeutic benefit of etodolac (Lodine 200) in rheumatological practice. An open clinical trial performed by 974 rheumatologists enabled an evaluation of efficacy, safety and therapeutic benefit of etodolac (Lodine 200) on 4,947 patients with rheumatoid arthritis, ankylosing spondylitis and osteoarthritis of the lower limbs; the initial dosage was 600 mg/d (for 2 weeks), then 400 to 600 mg/d (for 2 to 4 weeks, according to the indication). Efficacy, assessed by classical items for NSAID's, was shown to be excellent to good by 61-77 p. 100 of patients, according to the indication. 7.7 p. 100 of patients only dropped out for lack of efficacy. 20.4 p. 100 of patients developed adverse effect(s) (AE), but the relationship between etodolac and AE was assessed "possible" or "probable" only for 9.6 p. 100 of patients; this figure should be compared to the 7.6 p. 100 of patients who dropped out for AE and to the 92 p. 100 of patients who assessed the global safety as "excellent or good". The therapeutic benefit was estimated very favorable: 75 p. 100 of patients felt better than at the beginning of the study, 64.5 p. 100 of patients wished to continue the treatment and the (mean) benefit-risk ratio assessed with a logarithm scale (-1 to +1), ranged from 0.45 to 0.6 according to the indication. Therefore, this trial confirmed the good efficacy and safety profile of etodolac on a large scale in normal clinical practice in France, following assessments during controlled trials. It also permitted to perfect new items of evaluation for NSAID's, in particular for therapeutic benefit.

Adult↗
PubMedDate not supplied

[Lyme disease. Clinical, biological and developmental aspects. 29 cases in the Orléans region].

The description of Lyme's disease (LD) in 3 stages (like syphilis), has now become classical. 29 cases of LD, between June 1981 and November 1986, have been recorded at the Hospital in Orleans. The first twelve patients that were clinically diagnosed before the serology was introduced in France, have been recalled in order to search for possible late forms and assay their antibody level of anti-Borrelia burgdorferi. The preponderance of neurological forms (22 cases) and the scarcity of peripheral and/or arthralgic arthritis (8 cases) are emphasized by this study. Radiculalgias (18 cases in 22 meningo-radiculitis), especially in the lower extremities (14 cases), required hospitalization in rheumatology in 21 instances. Spinal algias (16 cases), were only isolated, at the time of hospitalization, in one case. The intense and nocturnal nature of the radiculalgias and spinal algias was noted in 17 of 18 cases, and 16 of 16 cases, respectively. Two atrio-ventricular blocks required hospitalization in cardiology. The long-term follow-up (3 to 5 years) of 12 patients revealed only 2 cases of severe asthenia and swelling at the puncture site in one case. There were no entesopathies nor chronic arthritis. The search for anti-Borrelia burgdorferi antibodies in the serum, was positive 24 times in 28. In the 4 cases where the serology was negative, the samplings were taken after a follow-up of more than three years in 3 instances.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗
PubMedDate not supplied

[Chronic arthritis in palmo-plantar pustulosis. Bacterid of Andrews].

Report of a 30 years old man story pustulosis palmaris et plantaris, spondylodiscitis L5-S1, right sterno-clavicular arthritis, right sacro-iliitis, and pubic symphysitis. Multiple bacteriologic investigations did not discover any infectious articular process. Histologic articular findings were inflammatory pattern, non steroid anti-inflammatory drugs corrected the arthritis. Anterior thoracic arthropathies are quasi-constant. Inflammatory spondylodiscitis are frequent, while sacro-iliac involvement is infrequent, this pattern distinguishing pustular arthro-osteitis from classic pelvispondylitis. Radiologic lesions are peculiar by predominance on one articular side at each site. Nosology is discussed. Slow infection by non virulent germs has been suspected , but seems improbable. This affection seems close seronegative spondylo-arthropathies and reactive arthritis, like acne conglobata arthritis for instance. Usual absence of HLA-B27 antigen must be noted.

Adult↗