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Biomedical subjects

C M Bailey

Publications and source records attributed to C M Bailey.

107 records · Page 6Linked to original sources

Cystic hygroma of the head and neck. A review of 37 cases.

37 children with cystic hygroma of the head and neck are reviewed. 92 per cent of the children required surgical excision of the cystic hygroma and one-third of these children suffered a permanent nerve palsy. Spontaneous resolution of the cystic hygroma occurred in 8 per cent of the children over a period of follow-up lasting on average 7 years 2 months (range 3 months-20 years). 41 per cent of the children suffered significant upper airway and feeding problems.

Airway Obstruction↗

Squamous papillomas of the larynx in adults. A review of 63 cases.

Sixty-three cases of squamous papillomas of the larynx occurring in adults are presented. Twelve cases started as juvenile papillomas and continued into adult life. Twice as many males as females were in the series. The papillomas were always present on the true vocal cords at presentation, although other parts of the larynx were involved to a variable extent. The symptom of hoarseness gave a good indication as to the state of the larynx during treatment. Malignancy did not develop in patients with papillomas which fulfilled the histological criteria. Papillomas are clusters of thin, cylindrical projections of squamous epithelial covered mucosa with second and even third order branching. Biopsies in 5 cases show papillomatosis of respiratory epithelium, a process which is here described in the larynx for the first time. The prognosis as regards recurrence for 20 patients with solitary lesions was good, for 38 patients with multiple lesions reasonable, but for 5 patients with extensive florid lesions was exceptionally poor.

Adolescent↗

Chondrosarcoma of the nasal septum.

The case history is presented of a patient with a massive chondrosarcoma arising from the posterior part of the nasal septum, extending into the base of the skull to involve the right middle cranial fossa. Removal of the main bulk of the tumour was accomplished by means of a cranio-facial resection, and it is hoped that useful palliation has thus been achieved. The literature relating to this rare tumour is reviewed: only seven cases have been previously described in which the tumour is believed to have arisen from the nasal septum. It is generally accepted that chondrosarcomas are radio-insensitive, and that surgical excision is the only effective form of treatment.

Adult↗

Onset of puberty in heifers of diverse beef breeds and crosses.

Puberty traits of straightbred and crossbred heifers (n = 301) were evaluated under pasture conditions. Breed groups represented were straightbred Hereford and Red Poll, reciprocal crosses of these two breeds, Angus X Hereford, Angus X Charolais-Cross, Brahman X Hereford and Brahman X Angus. Breed group was an important (P less than .01) source of variation in heifer weights and in age at puberty. Straight-bred Red Poll and Red Poll cross heifers were youngest at puberty, Angus X Hereford and Angus X Charolais-Cross were intermediate, and straightbred Hereford and Brahman crosses were oldest at the onset of puberty. At the beginning of their first mating season at 19.5 mo of age, 96% of the straightbred Red Polls, 95% of Red Poll crosses, 81% of Angus X Herefords, 89% of Angus X Charolais-Crosses, 68% of straightbred Herefords, 48% of Brahman X Herefords and 74% of the Brahman X Angus had attained puberty. Results of a diallel analysis of Hereford-Red Pool matings indicated that maternal influence of the Red Poll breed was superior (P less than .01) to Herefords for body weight up to 24 mo of age and incidence of puberty at 11.5 mo. Red Polls also exceeded Herefords in direct effects for puberty percentage at 11.5, 15 and 19.5 mo of age. Heterosis was significant for puberty percentage and weight. Breed group differences in pregnancy rate at 24 mo were not significantly.

Animals↗

Recovery from prolonged sensorineural hearing loss.

Five cases of sensorineural hearing loss are presented in which partial or complete recovery of hearing occurred after periods of deafness lasting from three months to more than five years. Three of the cases were diagnosed as Meniere's disease, one as sudden deafness of probable viral origin, and one as idiopathic sudden deafness. A review of the literature reveals brief mention of only a few similar cases, although it is suspected that the phenomenon is not as rare as these isolated reports suggest. It is proposed on the basis of experimental work in animals that the reversible deafness in these patients may be due to temporary obstruction of capillaries in the stria vascularis, which produces strial hypoxia resulting in a reduction in the endolymphatic potential, with consequent hearing loss.

Adult↗

Tuberculous laryngitis: a series of 37 patients.

A series of 27 cases of tuberculous laryngitis is reviewed to assess the diagnostic features of the disease. The condition generally presents in males of late middle age who have pulmonary tuberculosis, although the pulmonary disease is seldom advanced. The presenting symptom is usually hoarseness, and the laryngoscopic appearances frequently mimic a tumor or chronic non-specific laryngitis: few patients correspond to the classical descriptions of the disease found in old texts. Histological examination of biopsy material is usually the diagnostic procedure, emphasizing the difficulty of diagnosis in the general population.

Adult↗

Tuberculous otitis media: a series of 22 patients.

A series of 22 cases of tuberculous otitis media is reviewed to assess the diagnostic features of the disease. Significant clinical features are the presence of abundant pale granulations, an unexpectedly severe hearing loss, facial paralysis, the presence of normal mastoid cellular develpment and a past or family history of tuberculosis of any site. The otoscopic appearances of the tympanic membrane, and the symptom of painless otorrhea are not considered suspicious features. Histological examination of operative material was the diagnostic procedure in 20/22 cases, thus underlining the difficulty of diagnosis in a non-tuberculous general population. Treatment with antituberculous chemotherapy and surgery gives good results and recent indications are that tympanoplastic surgery may be useful.

Adolescent↗

Neonatal vocal cord paralysis.

The consultants agree that surgery is a common cause of unilateral vocal cord paralysis in neonates. In the absence of a history of surgery, they would evaluate a neonate for cardiovascular or central nervous system anomalies. None believes a relationship between laryngomalacia and vocal cord paralysis exists. But there is disagreement regarding the additional steps required to evaluate this child. The recommendations include endoscopy under general anesthesia with assessment of cricoarytenoid mobility, evaluation for other congenital anomalies, and observation of laryngeal dynamics (Dr. Benjamin), neurologic examination (Dr. Bailey), and no further testing (Dr. Gray). Laryngeal EMG in an infant is not an established technique and none of the consultants routinely performs this test. However, EMGs are part of the research protocol for one physician (Dr. Gray). The consensus is that aspiration is unlikely to be a problem in this case. However, if aspiration does occur, all would recommend conservative treatment. Feedings should be thickened and anti-reflux precautions taken. None was convinced that severe aspiration would be a problem. However, given the need for more aggressive treatment, the considerations would include collagen or Teflon injections or a tracheotomy (Dr. Gray) or a Nissen fundoplication, nasogastric tube feedings, or a gastrostomy (Dr. Bailey). Only one consultant would defer further treatment (Dr. Benjamin). The prognosis is generally good. Two consultants (Drs. Benjamin and Bailey) would follow a child with vocal cord paralysis by periodically repeating a laryngoscopic examination. A reinnervation procedure would be considered by one consultant at the age of 3 if the voice remains weak (Dr. Gray).

Diagnosis, Differential↗

Maternity experiences in a managed care organization.

We conducted a telephone survey of female managed care enrollees who recently had a normal vaginal delivery to examine the relationship between hospital length-of-stay and maternal characteristics, pregnancy factors, length-of-stay preferences, and postdischarge experiences. Results indicated that length-of-stay varied by maternal characteristics and pregnancy factors. Length-of-stay and maternal or newborn readmissions were not statistically associated. Most respondents reported that they would be willing to go home within twenty-four hours after future deliveries if additional services were provided. Emphasis should be placed on which services can be provided to prepare and assist mothers through the perinatal period.

Adolescent↗