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Biomedical subjects

C Perrin

Publications and source records attributed to C Perrin.

At least 181 records · Page 10Linked to original sources
PubMed1992

[Reconstruction of the mandibular arch using free vascularized iliac and scapular grafts. Arguments in favor of using scapular grafts].

In 12 cases of surgically removed mandibular symphysis malignancies, the bone and mouth floor were reconstructed using osteo-musculocutaneous flaps from the iliac crest or free osteo-cutaneous scapular flaps. In our experience, the latter provide the best results. Removed in dorsal decubitus, they allow floor replacement. During the dissection of the tumor site, we also preserve labial and clin structures, which favours a good restoration of phonation and swallowing.

Actuarial Analysis↗
PubMed1991

Immunohistologic analysis of the cholesteatoma matrix in children.

The immunohistological characteristics of retraction pockets, cholesteatoma matrix and granulomatous tissue were compared in 14 samples from pediatric cholesteatoma. The junction between epidermis and the middle ear mucosa appeared as the most inflammatory area, displaying the characteristics of delayed type hypersensitivity. CD1 + Langerhans cells were observed in all epidermic areas, but expressed class II molecules only in the vicinity of polymorphonuclear infiltrates. Numerous mast cells and IgA producing cells were also observed, suggesting that defenses from the mucosal immune system are summoned and contribute to the pathogenesis of cholesteatoma.

Adolescent↗
PubMed1991

Fixed-drug eruption presenting as an acute paronychia.

A case of fixed-drug eruption due to cefalexine presented with acute paronychia. Twenty days after a further challenge with a single dose of the drug, a biopsy of the affected skin showed intense expression for ICAM-1.

Aged↗
PubMed1991

[New concepts of the course of cholesteatoma from the immunohistological study of 96 samples].

The immunohistological characteristics of retraction pockets, cholesteatoma matrix and granulomatous tissue have been compared. Langerhans cells, epidemic folds and sub-epithelial tissue were labelled with specific markers (HLA II, adhesion receptors, KI 67). The junction between epidermis and sub-epithelial tissue of middle ear mucosa appeared as the most inflammatory area, displaying characteristics of delayed type hypersensitivity phenomenon. CD1+ Langerhans cells appear to express class II molecules only in the vicinity of polymorphonuclear infiltrates. Epidemic proliferation seems to able place mainly in the deepest recesses of the epidermis.

Acute Disease↗
PubMed1991

[External ear and abnormality of the urinary tract: a comparative study of 2 series (100 and 150 cases)].

Pinnal anomalies were observed in 46% of 150 children with urinary tract malformation. This ear feature was only recorded in 16 cases among 100 control children. The observation of abnormalities of the auricle (flattened structure of the pinna, deformed shape of the helix) should thus prompt to investigate a possible urinary tract malformation (vesico-renal reflux, mega-ureter). The identification of this disorder should occur as early as possible in order to perform corrective surgery before irreversible kidney damage. Any urinary disorder associated to atypical morphology of the external ear should lead to abdominal echography. Urinary infections, sometimes mistaken for upper respiratory tract infections, will sometimes provide a diagnostic lead, confirmed by cyto-bacteriological examination of urine. These observations further confirm the concomitant development of the external ear and urinary tract during embryogenesis.

Abnormalities, Multiple↗
PubMed1991

Posture in basketball players.

Static and dynamic posturography was recorded in eleven professional national basketball players (complete team). This sport requires balance and skill and is practiced by tall subjects (average height: 197 cm) with a history of 10 to 15 tibio-tarsal sprains. In static tests, with eyes open or closed, the way was similar between controls and players, while the area was increased for the latter. Area increment could be related to the history of ankle trauma reported by these subjects. In toes up dynamic tests, the latency of the first response (short latency response-myotatic reflex) was shorter in players. Data provided by national charts were used to compare posturography performance and player's skill. The best player who also ranks high in the national chart, has distinctive results in static posturography, with almost no difference when the test is performed with closed eyes.

Adolescent↗
PubMed1990

Lingual fibrosarcoma induced by 7, 12-dimethylbenzanthracene in the rat.

A single injection of 5 mg of 7, 12-dimethylbenzanthracene (DMBA) resulted in a high incidence of lingual fibrosarcoma in 67 Wistar rats. No metastases were found. We studied the influence of age and sex on the incidence, latency of tumors, loss of weight and the spontaneous survival of animals. The method described offers an experimental model for the study of cachexia resulting from upper digestive and respiratory tract cancer.

9,10-Dimethyl-1,2-benzanthracene↗
PubMed1990

[Skull vault bone graft in augmentation septorhinoplasty].

We describe our technique of augmentation rhinoplasty with bone grafting. Degloving is used as the surgical access in collapsed noses, and midcolumellar incision allows further buildup of the nasal contour. A V cutting is made on the dorsum to receive the graft. A split skull graft is taken with a drill and an osteotome. The sculpted bone implant is maintained in position with a miniaturized screw. We compare various bone grafts and types of surgical access.

Bone Transplantation↗
PubMed1990

[Use of the Galea flap in ORL].

We use the Galeal pericranial flap with the temporal vessels. Its high vascular content and its low esthetic and functional after effects are very interesting. The dissection between the outside of the flap and the subcutaneous tissue is difficult. The Galeal epicranial flap can cover wounds of orobuccopharynx, otopoiesis and loss of facial substance. We use it for arranging open technic and also for sealing the skull base.

Humans↗