[Bronchopulmonary lesions caused by aspiration (case reports)].
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Biomedical subjects
Publications and source records attributed to C Romano.
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In a group of 80 patients (50 male and 30 female) aged between 44 and 65, affected by alcoholic liver disease (46 with steatosis and 34 with liver cirrhosis) the Authors examined the relationship between the plasma lipid, in particular of Lp(a), and the incidence of vascular atherosclerotic plaques. The results were compared with those found in the controls (50 subjects of similar age, social and working status to that of the above patients but nondrinkers without liver or other metabolic disease). In the patients with steatosis we found a moderate increase in plasma lipid fractions including total, HDL and LDL cholesterol, but low levels of Lp(a), with an incidence of arterial plaques of 10.86%. In those with liver cirrhosis the findings were characterized by low levels of lipids and in particular of Lp(a), with an incidence of arterial plaques of 8.82%, decidedly less marked than in the controls (16%). In both cases the low incidence of vascular involvement appears to be in some way linked with low levels of Lp(a) and the severity of liver disease and not with the behaviour of HDL cholesterol.
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The authors describe a case day Guillain-Barré syndrome admitted in pediatrics hospital department for asthenia. Approximately an hour after admission, the patient showed dysphagia and respiratory insufficiency and was diagnosed a Guillain-Barré syndrome, successfully treated.
Carboxyhemoglobin (COHb) and methemoglobin (MetHb) values in blood were measured in a population of 296 asymptomatic conscripts who were not under medical treatment and had no occupational exposure. The mean COHb value was 3.25 (S.D. = 1.45%) in smokers and 1.34 (S.D. = 0.8) in non-smokers, with a wide variability in both subgroups, particularly among smokers. The COHb levels in moderate smokers were lower than in heavy smokers, but smoking just before the blood test greatly increased the COHb levels. Non-smoking country dwellers had lower COHb levels than non-smoking city dwellers, but the COHb levels of smokers were independent of residence and were only smoking-related. The sample MetHb level was 0.81 (S.D. = 0.37) and was influenced by country living and smoking. Levels were lowest in non-smoking country dwellers (0.66, S.D. = 0.38%) and increased with moderate smoking (0.71, S.D. = 0.40%). Heavy smoker levels were independent of residence. Smoking just before the blood test had no effect on the value.
The paper analyzes the 8 KHz threshold in subjects with noise-induced hearing loss. The study group consisted of 315 subjects occupationally exposed to noise and suffering from acoustic trauma, which was considered as a mean threshold of more than 25 dB at 2, 3 and 4 KHz. The mean shape of audiograms was characterized by a neurosensory deficit which was more elevated at 4 and 6 KHz whereas the threshold at 8 KHz was better. However, this pattern was found in 60% of the cases whereas in the remaining 40% the threshold at 8 KHz was worse. Subjects with the most impaired audiometric threshold at 8 KHz were mainly older, although cases were found in a low percentage of younger subjects. The results demonstrate that in individual cases it is impossible, on the basis of the shape of the audiogram, to establish whether a hearing loss is due to noise or age.
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The aim of this study was to determine the relationship existing between auditory disability, according to WHO 1980, and pure tone audiometry threshold in noise induced hearing loss. Disability was evaluated on the basis of a questionnaire submitted to 286 subjects with acoustic trauma. Answers obtained were considered reliable on the basis of statistical analysis. Results showed that subjects with disability have an higher pure tone threshold than subjects without auditory disability. However it appears difficult to determine a precise threshold level ever which auditory disability may be considered present. The Authors suggest that this limit could be determined on the basis of pure tone threshold at the 10th centile of the group of subjects with disability or at the 90th centile of subjects without disability.
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The Authors report a case of difficult diagnosis, clinically characterised by long-term persistent fever. Clinical and laboratory tests led to a first conclusion of a tubercular infection; later of a perisplenic hematoma and the persistence of high inflammatory indices directed to a different diagnosis.