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Biomedical subjects

C Romano

Publications and source records attributed to C Romano.

420 records · Page 24Linked to original sources
PubMedDate not supplied

[Determination of the onset of occupational hearing loss].

The paper examines the different aspects of the diagnosis of noise induced hearing disability and handicap. In the author's opinion a diagnosis of this kind can be made only if both an occupational acoustic trauma and a hearing disability or handicap are present. An occupational acoustic trauma can be considered to be present if the subject works in a noisy environment, if there are no auditory diseases other than of occupational origin, and if the audiometric threshold is neurosensorial, bilateral, more elevated at the higher frequencies and higher than the threshold of subjects on the same age but not exposed to industrial noise. On the other hand, the authors deem that there is a loss of hearing function when hearing disability and handicap are present according to the WHO definition. An experimental model is proposed that will establish the presence of hearing disability and handicap.

Audiometry↗
PubMedDate not supplied

[Microbiology of chronic lung diseases in children (author's transl)].

The bacterial flora was studied in the bronchial, pharyngeal secretions and sputum of 80 children with Cystic Fibrosis (CF) and of 21 children with other chronic lung diseases, treated at the Pediatric Clinic (Respiratory Unit), University of Genoa. Staphylococcus aureus was found in 52% of patients, Pseudomonas aeruginosa in 48%, Proteus in 5%. According to the age, the patients have been distinguished into four groups; in the 6-10 and 11-15 year-old group Staphylococcus aureus was the commonest pathogen isolated, while Pseudomonas aeruginosa was found much more commonly in the 16-20 year-old group. Details are given of antibiotic-sensitivity for single strains grown. Intensive care programs, based on specific antibiotic-sensitivity, for in-patients and out-patients, are reported: positive results in treatment courses with Gentamicin, Cephalosporins and Tobramycin are presented.

Adolescent↗
PubMedDate not supplied

[Study of suprarenal cysts. Apropos of a case of cystic lymphagioma of the adrenal glands].

Following a review of the literature on the incidence and characteristics of suprarenal cysts, the case of a young woman who was suffering from bland urinary symptomatology is reported. On the basis of anatomopathological study, the case was classified as a cystic lymphangioma of the suprarenal gland arising on a malformative base.

Adrenal Gland Neoplasms↗
PubMedDate not supplied

[Primary biliary cirrhosis].

PURPOSE: To discuss exhaustively: clinical, serological and pathologic aspects of primary biliary cirrhosis (CBP); recent advantages in the knowledge of the disease's pathogenesis, therapeutical approaches that still appear less preferable than liver transplantation. DESIGN: We reviewed the most important recent studios on CBP. RESULTS: More than 90% of patients have antimitochondrial antibodies, so that CBP can be considered an autoimmune disease. Inciting agents could be either PDC E2-like or MHC molecules. An autoaggressive mechanism against biliary ducts could be the following: the neo-antigen on the surface of biliary tract cells could be the target for the immunological damage; anti PDC-E2 antimitochondrial antibodies could be secondary to the cellular damage and to the release of mitochondrial enzymes. CONCLUSIONS: In primary biliary cirrhosis, several circumstances (specificity of biliary-ductal destruction, lymphocyte infiltration of portal tract, abnormal expression of HLA-DR on surface of biliary epithelium cells) suggest that the epithelial cells of intrahepatic biliary ducts are the target of a severe and isolated immune response. The identification of the E2-like PDC antigen is a significant achievement in the knowledge of the pathogenetic process. On this basis, it is now to investigate possible genetic markers of risk and to clarify the role of T cells in the immunopathogenesis of the illness. The only effective treatment for CBP is liver transplantation.

Autoimmune Diseases↗