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Biomedical subjects

C Romo-Barrientos

Publications and source records attributed to C Romo-Barrientos.

3 recordsLinked to original sources

[Use of antiparkinsonian agents in Castilla-La Mancha. Estimate of prevalence of Parkinson disease].

INTRODUCTION: Research concerning the prevalence of Parkinson disease (PD) are scarce; in addition with different methodologies. Therefore it is not possible to determine its true impact on public health in Castilla-La Mancha (CLM), Spain. OBJECTIVE: Determine the prevalence of PD in CLM (332.0 and 332.1 of the ICD-9th revision) by the consumption of antiparkinsonian drugs. PATIENTS AND METHODS: Calculating the daily defined doses (DDD) per 100,000 inhabitants (10(5)) for each of the prescribed antiparkinsonian drugs (Therapeutic Group, N04A), during 1994-1996 for each of the province of CLM. The data from prescriptions have been obtained from the Pharmaceutical Service of the Health and Consume Ministry of Spain, which cover 100% of the population. RESULTS: The DDD determination's of L-Dopa per 10(5) inhabitants, a prevalence of 270.24 (IC 95%: 239.2-304.7) is estimated for the whole population. The consumption of L-Dopa by provinces and years (1994-1996) allows to know the distribution of PD in CLM. CONCLUSIONS: The numbers obtained place to CLM in a middle-high prevalence; although methodological differences do not allow definitive conclusions.

Aged↗

[Factors associated with the degree of disability among patients of the Spanish Multiple Sclerosis Association of the Community of Madrid].

INTRODUCTION: Multiple sclerosis (MS) causes a degree of disability in young adults which hampers everyday activities. The aetiology and predisposing factors are unknown. OBJECTIVE: To find the degree of disability (DD) and index of progression (IP) together with the possible associated prognostic factors in MS patients of the Spanish Multiple Sclerosis Association (AEDEM). MATERIAL AND METHODS: Transverse design based on the population (AEDEM) by means of a representative sample (N = 158), taken randomly from those not suffering an exacerbation of MS. A telephone survey was carried out using the 'Minimum Dossier of Invalidity of MS' (eliminating variables concerning neurological dysfunction). The relationship between DD and IP, with different variables, was compared using parametric and non-parametric tests. Variables associated with the evolution of DD were measured in terms of the Odds Ratio. RESULTS: The response rate was 150 (94.9%), 10 (6.7%) were rejected, giving a total of 140 patients. 55% of the patients considered themselves to be independent to some degree, in that they had no difficulty with everyday activities. Difficulty with walking was the 'most disabling problem' of 47.1%. Progression of the disorder (IP) depended on the frequency of exacerbations (r = 0.63). The variables associated with a raised DD are: suffer more than 5 exacerbations (OR: 3.73), have had the illness for more than 15 years (OR = 3.29) and a current age of over 35 years old (OR = 2.86). CONCLUSIONS: The reduction in number and frequency of exacerbations or their prevention may reduce progression of the disorder and disability in daily life.

Adolescent↗

[Executive dysfunction in attention deficit hyperactivity disorder in childhood].

INTRODUCTION: The principal problem of ADHD is the difficulty to execute inhibitory control. The inhibition is an executive function that is develop during childhood. AIM: To know if other executive functions shower a lower performance in ADHD versus control group and these were different between ADHD-I and ADHD-C. PATIENTS AND METHODS: Fifty three children, between 7 to 10 years old, participated and were assess with EMIC and Simon task. RESULTS: The results showed similar profile in working memory and verbal span. In contrast, ADHD-C showed lower performance in Simon task and more impulsively. On an other hand, ADHD-I showed lower performance in memory working tasks and planning. CONCLUSIONS: These results suggest differences in the executive profile between ADHD-I and ADHD-C and these support the hypothesis of Barkley about the necessity to differ both clinical subtypes.

Attention Deficit Disorder with Hyperactivity↗