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Biomedical subjects

C Skorpik

Publications and source records attributed to C Skorpik.

At least 55 records · Page 3Linked to original sources
PubMed1987

Trabeculectomy and intraocular lens implantation: a combined procedure.

We present the results achieved in 26 cases of trabeculectomy combined with intraocular lens implantation after extracapsular surgery in eyes with open-angle glaucoma. Phacoemulsification was performed in nine cases, planned extracapsular cataract extraction in 17. In 23 eyes, a posterior chamber lens was implanted; in three eyes an anterior chamber lens was used because of a ruptured posterior capsule. After a follow-up period ranging from four to 29 months, the postoperative results were satisfactory in all eyes treated. The patients achieved postoperative intraocular pressure of 20 mm Hg or less. In 28% of the cases, however, additional antiglaucomatous medication is required. Given proper indications and present-day surgical techniques, this combined procedure provides effective one-time treatment for cataract and glaucoma patients as well as optimal visual rehabilitation.

Aged↗
PubMed1987

Clinicopathologic findings after in-the-bag implantation of open-loop polymethylmethacrylate and silicone lenses in the rabbit eye.

Two lens models, one all silicone with J-loop haptics, the second with PMMA optics and angled polypropylene C-loop haptics, were implanted in the capsular bag of 36 rabbit eyes following extracapsular lens extraction. Technical ease of implantation, inflammatory response, lens position, and fibrin exudation as well as precipitate formation were examined. Biomicroscopy, light and phase-contrast microscopy were used. Differences in haptic vulnerability, lens position, and fibrin clot formation were found between the two lens types. Lens-specific differences in precipitate formation could not be substantiated.

Animals↗
PubMed1987

Optical resolution of silicone and polymethylmethacrylate intraocular lenses.

The optical resolution and contrast of 18 silicone and 18 polymethylmethacrylate (PMMA) intraocular lenses were determined before implantation in and after removal from rabbit eyes. A specially designed microphotographic system that allows documentation and comparison of the image quality of different lens types was used. Silicone intraocular lenses showed a mean axial resolution of 1.25, PMMA lenses showed 1.60, of an optotype analogous resolution target (1.0 = 20/20) at a 3 mm pupil opening preoperatively. At one to 16 weeks postoperatively, both types of IOLs demonstrated nearly unchanged resolution. Contrast, however, decreased to between 60% and 85% of the preoperative 100% standard. This decrease was due to precipitates deposited on the lens surface, to posterior capsule opacification, and to lens decentration.

Animals↗
PubMed1987

Evaluation of 50 silicone posterior chamber lens implantations.

This study presents our experience with 50 silicone intraocular lens (IOL) implants (STAAR Surgical Company, model AA-4004) in the posterior chamber. In the relatively short-term mean postoperative follow-up of seven months, the following complications were observed: iris chafing - pigmentary dispersion, 15 (30%); IOL tilt and decentration, 7 (14%); pseudophakodonesis, 6 (12%); fibrinous exudate, 3 (6%); luxation of one haptic in the anterior chamber, 1 (2%); IOL tears, 5 (10%). Visual acuity of 20/20 to 20/40 was obtained in 40 patients (80%). Although no severe consequences were noted, the long-term effects of the complications are unpredictable at present.

Aged↗
PubMed1987

[Initial experiences with primary silicone oil administration into the vitreous cavity in complicated eye injuries].

The authors report on five cases of severe perforating injury of the posterior segment which were initially treated by vitrectomy and subsequent filling of the vitreous cavity with silicone oil. The results so far have been satisfactory in all eyes. The advantages of the method (e.g., tamponade of retinal tears, facilitation of postoperative laser treatment) are emphasized and possible side effects are discussed.

Eye Foreign Bodies↗
PubMed1987

High-energy electrons used to inhibit experimental intraocular proliferation and detachment.

Irradiation of rabbit eyes with high-energy electrons was used to test the inhibition of experimental intraocular proliferation and retinal detachment, produced by intravitreal implantation of 250,000 homologous fibroblasts. After irradiation with 2,000 rad, started 5 days after implantation, 45% of eyes (9 of 20) still manifested traction detachment. When the dose was increased to 3,000 rad and radiation treatment was started 1 day after implantation, proliferation and traction detachment were observed in only 10% of eyes (2 of 20). No acute damage to retinal tissue or nerve fibers was observed. Because it is easily available, simple in application and dose adjustment, and without toxic side effects, radiation therapy should be considered as an effective alternative to drug treatment for the inhibition of intraocular proliferation and detachment. Statistically significant results of this investigation suggest its use combined with surgery in certain reproliferative cases in man.

Animals↗
PubMed1986

Recent advances in preservation of viable corneal tissue.

Increasing numbers of preserved corneas are being transplanted as the demand for optimal bioavailability for donor corneas increases. McCarey-Kaufman (MK) short-term storage provides a sufficient endothelial cell viability for a maximum of only 4 days. Organ culture of corneoscleral discs extends post mortem storage times up to 4 weeks. K-Sol, a new cornea storage medium with 2.5% chondroitin sulfate, containing no calf serum as source of foreign protein and no dextran as artificial dehydrating agent, permits tissue to be used for at least 2 weeks after enucleation stored at 4 degrees C. The corneal endothelium was intact, as demonstrated by subsequent vital staining and phase microscope evaluation. Pachymetric measurements showed regular thinning profiles in 31 K-Sol preserved corneas for corneal transplantation, with a clear outcome after a preliminary average observation time of six months.

Adolescent↗
PubMed1986

[Cyanoacrylate tissue gluing in corneal perforations].

Three cases of corneal perforation which were treated with tissue adhesive (Histoacryl) are reported. The first case showed free fistulation after perforating keratoplasty, whilst the second had a trophic ulcer and the third had a traumatic corneal laceration with loss of corneal tissue. Treatment was successful in all three cases. The surgical technique, results and possible complications are mentioned.

Adult↗
PubMed1986

[Reconstruction of the medial canthal area and lower eyelid].

This paper presents the case report of a patient with an extensive tumour of the lower eyelid and the medial canthal area treated by a combination of two surgical procedures. We combined the method described by Hughes and modified by Smith--a tarsoconjunctival graft from the upper eyelid--for reconstruction of the canthal area with a Tenzel lateral rotation skin flap. The combination of these methods enables the transplanted part of the tarsal tissue to be kept relatively small, which reduces the risk of postoperative complications of the upper eyelid. Moreover, with the rotation flap it is possible to control the tension of the lower eyelid exactly. The postoperative result is satisfactory.

Aged↗
PubMed1986

An intraocular balloon for silicone oil implantation.

This study reports 14 patients who presented proliferative vitreoretinopathy (PVR) at stages III to IV, as well as ora dialysis or large retinal breaks of such extent that it was evident that implanted silicone oil would penetrate behind the retina. We used a latex balloon catheter, which was introduced in aphakic eyes into the vitreous cavity, following pars plana vitrectomy and removal of pre- and sometimes subretinal membranes. Under direct observation, the balloon was filled with silicone oil until the balloon occupied the entire globe while the intravitreal and subretinal fluid was drained. Subsequently, the balloon was punctured at the opposite side of the scleral incision so that the silicone oil could drain into the vitreous cavity. The balloon was then slowly withdrawn from the eye. Complications were pre- and subretinal hemorrhages, retinal dialysis behind (2X) and vis-à-vis (4X) the incision. In none of the cases was silicone oil observed to have penetrated behind the retina.

Drug Implants↗
PubMed1986

[Argon laser trabeculoplasty in simple glaucoma].

In June 1984 the authors started a prospective study on the treatment of open-angle glaucoma with argon laser trabeculoplasty. The technique used was to treat 180 degrees of the anterior nonpigmented part of the trabecular meshwork with 80 to 100 burns. For retreatment the posterior pigmented part of the trabecular meshwork was coagulated with 80 to 100 burns. The burns were always applied to the pretreated half of the meshwork. At present the study includes 47 eyes treated posteriorly. Of these cases 12 eyes required retreatment. Five eyes had previously undergone an unsuccessful trabeculectomy. The preliminary results are satisfactory. The average reduction in intraocular pressure was 5.9 mm Hg; the mean intraocular pressure before therapy was 23 mm Hg. In 8 cases the trabeculoplasty failed, making a fistulating procedure necessary. The treatment was always well tolerated and there were only minor side effects which never led to any lasting damage.

Adult↗
PubMed1986

[Temporary silicone oil implantation following vitrectomy in proliferative diabetic retinopathy].

Report on 23 patients with proliferative diabetic retinopathy who underwent silicone oil implantation due to recurrent intravitreal hemorrhages following pars plana vitrectomy. Postoperatively, it was possible to perform panretinal laser photocoagulation without difficulty or haste. After an average period of 4 months, silicone oil was removed from 10 eyes. Subsequent hemorrhages in 4 of these eyes are due to diabetic retinopathy, not to silicone oil. In 6 cases, silicone oil removal is planned for the near future; in a further 7 cases, silicone oil removal has been postponed because of the potential danger of further traction retinal detachment.

Diabetic Retinopathy↗
PubMed1985

[Results after planned extracapsular cataract extraction with the Klöti stripper and implantation of UV light-absorbent Simcoe lenses with a 10-degree loop tilt].

Planned ECCE remains a valuable alternative to phacoemulsification due to its protection of the endothelial cells of the cornea. In contrast to the most commonly used infusion-aspiration systems, Kloeti's vitreous stripper provides, in addition, an excellent cutting mechanism enabling the removal of hard parts of the parenchyma or capsular remnants. The aspheric shaped UV light absorbing Simcoe lenses with a 10 grade loop angle used as lens replacement over the past 2 years in 300 cases did not cause any noteworthy complications. In 94% of cases a visual acuity of at least 0.5 was achieved; no case of cystoid macular edema has been observed so far.

Cataract Extraction↗
PubMed1985

[Treatment of cystoid macular edema after intracapsular cataract extraction and implantation of the Binkhorst 4-loop lens].

This paper presents a report on 8 eyes in which cystoid macular edema developed between 6 months and 3 years after intracapsular cataract surgery combined with 4 loop lens implantation. Topical indomethacin treatment undertaken for at least 3 months proved ineffective. In view of additional progressive damage to the inferior part of the iris due to the inferior lens loops as well as recurrent microhaemorrhages in the anterior chamber, the iris clip lens was removed and after thorough anterior vitrectomy with Kloeti's stripper a Shepard anterior chamber lens was implanted. Indomethacin treatment 3 to 4 times daily was continued postoperatively for up to 8 months. Evident improvement in visual acuity was noted in 5 eyes, whilst in the remaining 3 eyes the procedure had probably been carried out too late.

Aged↗
PubMed1985

[Posterior chamber lens implantation after removal of an intralens metallic foreign body].

This paper presents a case report of posterior chamber lens implantation after a perforating eye injury. We failed to extract the foreign body with a hand magnet and to close the capsule wound by application of a fibrin tissue adhesive. The posterior capsule was intact, and hence we performed an extracapsular cataract extraction with implantation of a posterior chamber lens. The foreign body was expressed together with the nucleus. The functional result is satisfactory.

Anterior Chamber↗
PubMed1985

[Immunosuppressive therapy with cyclosporin A following penetrating keratoplasty].

Report on 11 patients who underwent penetrating keratoplasty and were treated with Cyclosporin A for an average of 6 months because of excessive superficial and deep vascularization of the recipient cornea. In none of the patients was a permanent Cyclosporin A-induced side-effect observed. After an average follow-up period of 11 months 9 grafts remained completely clear; however, an allograft-reaction occurred in 2 cases in spite of the immunosuppressive therapy.

Corneal Diseases↗